| Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs Z Li, C Ender, G Meister, PS Moore, Y Chang, B John Nucleic acids research 40 (14), 6787-6799, 2012 | 358 | 2012 |
| A sensitive non-radioactive northern blot method to detect small RNAs SW Kim, Z Li, PS Moore, AP Monaghan, Y Chang, M Nichols, B John Nucleic acids research 38 (7), e98-e98, 2010 | 327 | 2010 |
| A new perspective in the field of cardiac safety testing through the comprehensive in vitro proarrhythmia assay paradigm B Fermini, JC Hancox, N Abi-Gerges, M Bridgland-Taylor, KW Chaudhary, ... Journal of biomolecular screening 21 (1), 1-11, 2016 | 313 | 2016 |
| Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment S Dutta, KC Chang, KA Beattie, J Sheng, PN Tran, WW Wu, M Wu, ... Frontiers in Physiology 8, 616, 2017 | 200 | 2017 |
| Improving the in silico assessment of proarrhythmia risk by combining hERG (human ether-à-go-go-related gene) channel–drug binding kinetics and multichannel pharmacology Z Li, S Dutta, J Sheng, PN Tran, W Wu, K Chang, T Mdluli, DG Strauss, ... Circulation: Arrhythmia and Electrophysiology 10 (2), e004628, 2017 | 184 | 2017 |
| An in-depth map of polyadenylation sites in cancer Y Lin, Z Li, F Ozsolak, SW Kim, G Arango-Argoty, TT Liu, SA Tenenbaum, ... Nucleic acids research 40 (17), 8460-8471, 2012 | 166 | 2012 |
| Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative Z Li, BJ Ridder, X Han, WW Wu, J Sheng, PN Tran, M Wu, A Randolph, ... Clinical Pharmacology & Therapeutics 105 (2), 466-475, 2019 | 155 | 2019 |
| Mechanistic model‐informed proarrhythmic risk assessment of drugs: review of the “CiPA” initiative and design of a prospective clinical validation study J Vicente, R Zusterzeel, L Johannesen, J Mason, P Sager, V Patel, ... Clinical Pharmacology & Therapeutics 103 (1), 54-66, 2018 | 130 | 2018 |
| Regulatory circuit of human microRNA biogenesis J Lee, Z Li, R Brower-Sinning, B John PLoS Computational Biology 3 (4), e67, 2007 | 98 | 2007 |
| Comprehensive in vitro proarrhythmia assay (CiPA) update from a cardiac safety research consortium/health and environmental sciences institute/FDA meeting DG Strauss, G Gintant, Z Li, W Wu, K Blinova, J Vicente, JR Turner, ... Therapeutic Innovation & Regulatory Science 53 (4), 519-525, 2019 | 96 | 2019 |
| Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment KC Chang, S Dutta, GR Mirams, KA Beattie, J Sheng, PN Tran, M Wu, ... Frontiers in physiology 8, 917, 2017 | 93 | 2017 |
| General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy Z Li, GR Mirams, T Yoshinaga, BJ Ridder, X Han, JE Chen, ... Clinical Pharmacology & Therapeutics 107 (1), 102-111, 2020 | 86 | 2020 |
| Translational models and tools to reduce clinical trials and improve regulatory decision making for QTc and proarrhythmia risk (ICH E14/S7B updates) DG Strauss, WW Wu, Z Li, J Koerner, C Garnett Clinical Pharmacology & Therapeutics 109 (2), 319-333, 2021 | 79 | 2021 |
| Identification, expression and functional characterization of the GRAL gene Z Li, B Wang, X Wu, SY Cheng, L Paraoan, J Zhou Journal of neurochemistry 95 (2), 361-376, 2005 | 72 | 2005 |
| The effect of antibiotics on the gut microbiome: a metagenomics analysis of microbial shift and gut antibiotic resistance in antibiotic treated mice L Xu, A Surathu, I Raplee, A Chockalingam, S Stewart, L Walker, L Sacks, ... BMC genomics 21, 1-18, 2020 | 62 | 2020 |
| Characterization of viral and human RNAs smaller than canonical MicroRNAs Z Li, SW Kim, Y Lin, PS Moore, Y Chang, B John Journal of virology 83 (24), 12751-12758, 2009 | 59 | 2009 |
| Ventral mesencephalon-enriched genes that regulate the development of dopaminergic neurons in vivo M Yin, S Liu, Y Yin, S Li, Z Li, X Wu, B Zhang, SL Ang, Y Ding, J Zhou Journal of Neuroscience 29 (16), 5170-5182, 2009 | 47 | 2009 |
| A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm BJ Ridder, DJ Leishman, M Bridgland-Taylor, M Samieegohar, X Han, ... Toxicology and Applied Pharmacology 394, 114961, 2020 | 43 | 2020 |
| A temperature-dependent in silico model of the human ether-à-go-go-related (hERG) gene channel Z Li, S Dutta, J Sheng, PN Tran, W Wu, T Colatsky Journal of pharmacological and toxicological methods 81, 233-239, 2016 | 43 | 2016 |
| Development of a translational model to assess the impact of opioid overdose and naloxone dosing on respiratory depression and cardiac arrest J Mann, M Samieegohar, A Chaturbedi, J Zirkle, X Han, SF Ahmadi, ... Clinical Pharmacology & Therapeutics 112 (5), 1020-1032, 2022 | 38 | 2022 |
