| Neuroprotective effect of Biochanin a against Bisphenol A-induced prenatal neurotoxicity in zebrafish by modulating oxidative stress and locomotory defects B Haridevamuthu, A Guru, R Murugan, G Sudhakaran, R Pachaiappan, ... Neuroscience Letters 790, 136889, 2022 | 47 | 2022 |
| Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of … G Sudhakaran, P Prathap, A Guru, B Haridevamuthu, R Murugan, ... Molecular and cellular biochemistry 477 (10), 2387-2401, 2022 | 47 | 2022 |
| Anti‐inflammatory role demonstrated both in vitro and in vivo models using nonsteroidal tetranortriterpenoid, Nimbin (N1) and its analogs (N2 and N3) that alleviate the … G Sudhakaran, P Prathap, A Guru, R Rajesh, S Sathish, T Madhavan, ... Cell Biology International 46 (5), 771-791, 2022 | 46 | 2022 |
| Withaferin A targets the membrane of Pseudomonas aeruginosa and mitigates the inflammation in zebrafish larvae; an in vitro and in vivo approach R Murugan, R Rajesh, B Seenivasan, B Haridevamuthu, G Sudhakaran, ... Microbial Pathogenesis 172, 105778, 2022 | 43 | 2022 |
| Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection A Guru, G Sudhakaran, M Velayutham, R Murugan, R Pachaiappan, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2022 | 36 | 2022 |
| Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian PCOS model G Sudhakaran, A Guru, BHD Muthu, R Murugan, A Arshad, J Arockiaraj Life Sciences 291, 120276, 2022 | 35 | 2022 |
| Molecular properties of postbiotics and their role in controlling aquaculture diseases G Sudhakaran, A Guru, B Haridevamuthu, R Murugan, A Arshad, ... Aquaculture Research 53 (9), 3257-3273, 2022 | 34 | 2022 |
| Protective effect of morin by targeting mitochondrial reactive oxygen species induced by hydrogen peroxide demonstrated at a molecular level in MDCK epithelial cells PK Issac, M Velayutham, A Guru, G Sudhakaran, R Pachaiappan, ... Molecular Biology Reports 49 (6), 4269-4279, 2022 | 30 | 2022 |
| Copper sulfate induced toxicological impact on in-vivo zebrafish larval model protected due to acacetin via anti-inflammatory and glutathione redox mechanism M Singh, A Guru, G Sudhakaran, R Pachaiappan, S Mahboob, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2022 | 29 | 2022 |
| Anti-Cancer and Anti-Inflammatory Activities of a Short Molecule, PS14 Derived from the Virulent Cellulose Binding Domain of Aphanomyces invadans, on Human … M Velayutham, P Sarkar, G Sudhakaran, KA Al-Ghanim, S Maboob, ... Molecules 27 (21), 7333, 2022 | 24 | 2022 |
| Nimbin analog N2 alleviates high testosterone induced oxidative stress in CHO cells and alters the expression of Tox3 and Dennd1a signal transduction pathway … G Sudhakaran, R Rajesh, R Murugan, M Velayutham, A Guru, S Boopathi, ... Phytotherapy Research 37 (4), 1449-1461, 2023 | 21 | 2023 |
| β-cells regeneration by WL15 of cysteine and glycine-rich protein 2 which reduces alloxan induced β-cell dysfunction and oxidative stress through phosphoenolpyruvate … A Guru, G Sudhakaran, MH Almutairi, BO Almutairi, A Juliet, J Arockiaraj Molecular Biology Reports 49 (12), 11867-11879, 2022 | 18 | 2022 |
| Deacetylated nimbin analog N2 fortifies alloxan-induced pancreatic β-cell damage in insulin-resistant zebrafish larvae by upregulating phosphoenolpyruvate carboxykinase (PEPCK … G Sudhakaran, R Rajesh, A Guru, B Haridevamuthu, R Murugan, ... Toxicology and Applied Pharmacology 454, 116229, 2022 | 15 | 2022 |
| 6‐Gingerdione reduces apoptotic conditions in HepG2 cells and inhibits inflammatory cytokine gene expression in alcoholic liver injured zebrafish larvae A Guru, T Manjunathan, G Sudhakaran, A Juliet, P Gopinath, J Arockiaraj Chemistry & Biodiversity 20 (1), e202200959, 2023 | 14 | 2023 |
| Unravelling the epigenetic impact: Oxidative stress and its role in male infertility-associated sperm dysfunction G Sudhakaran, D Kesavan, K Kandaswamy, A Guru, J Arockiaraj Reproductive Toxicology, 108531, 2024 | 13 | 2024 |
| Neurobehavioral impairments from chromium exposure: insights from a zebrafish model and drug validation S Boopathi, B Haridevamuthu, A Gandhi, SPRR Nayak, G Sudhakaran, ... Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2024 | 13 | 2024 |
| Microbiome analysis of Litopenaeus vannamei reveals Vibrio as main risk factor of white faeces syndrome S Boopathi, R Meenatchi, P Brindangnanam, G Sudhakaran, MS Coumar, ... Aquaculture 576, 739829, 2023 | 12 | 2023 |
| Nimbin analogs N5 and N7 regulate the expression of lipid metabolic genes and inhibit lipid accumulation in high-fat diet-induced zebrafish larvae: An antihyperlipidemic study G Sudhakaran, R Rajesh, A Guru, MV Arasu, P Gopinath, J Arockiaraj Tissue and Cell 80, 102000, 2023 | 12 | 2023 |
| Ophthalmic intervention of naringenin decreases vascular endothelial growth factor by counteracting oxidative stress and cellular damage in in vivo zebrafish G Sudhakaran, A Chandran, AR Sreekutty, S Madesh, R Pachaiappan, ... Molecules 28 (14), 5350, 2023 | 9 | 2023 |
| Updated experimental cellular models to study polycystic ovarian syndrome G Sudhakaran, SR Babu, H Mahendra, J Arockiaraj Life Sciences 322, 121672, 2023 | 9 | 2023 |
Dr. R. Ajay GuruScientist, Saveetha Institute of Medical and Technical ScienceAdresse e-mail validée de saveetha.com