| Comprehensive and integrative genomic characterization of hepatocellular carcinoma A Ally, M Balasundaram, R Carlsen, E Chuah, A Clarke, N Dhalla, RA Holt, ... Cell 169 (7), 1327-1341. e23, 2017 | 2094 | 2017 |
| Evolutionary action score of TP53 identifies high-risk mutations associated with decreased survival and increased distant metastases in head and neck cancer DM Neskey, AA Osman, TJ Ow, P Katsonis, T McDonald, SC Hicks, ... Cancer research 75 (7), 1527-1536, 2015 | 176 | 2015 |
| Single nucleotide variations: biological impact and theoretical interpretation P Katsonis, A Koire, SJ Wilson, TK Hsu, RC Lua, AD Wilkins, O Lichtarge Protein Science 23 (12), 1650-1666, 2014 | 157 | 2014 |
| Deleterious effect of RAS and evolutionary high-risk TP53 double mutation in colorectal liver metastases YS Chun, G Passot, S Yamashita, M Nusrat, P Katsonis, JM Loree, ... Annals of surgery 269 (5), 917-923, 2019 | 146 | 2019 |
| Mitochondrial neurogastrointestinal encephalopathy due to mutations in RRM2B A Shaibani, OA Shchelochkov, S Zhang, P Katsonis, O Lichtarge, ... Archives of neurology 66 (8), 1028-1032, 2009 | 144 | 2009 |
| A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness P Katsonis, O Lichtarge Genome research 24 (12), 2050-2058, 2014 | 143 | 2014 |
| Metastable liquid clusters in super-and undersaturated protein solutions O Gliko, W Pan, P Katsonis, N Neumaier, O Galkin, S Weinkauf, ... The Journal of Physical Chemistry B 111 (12), 3106-3114, 2007 | 140 | 2007 |
| Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-Risk TP53 Mutations in Head and Neck Cancer through Mitotic Arrest Followed by … AA Osman, MM Monroe, MV Ortega Alves, AA Patel, P Katsonis, ... Molecular cancer therapeutics 14 (2), 608-619, 2015 | 120 | 2015 |
| Evolutionary action score of TP53 coding variants is predictive of platinum response in head and neck cancer patients AA Osman, DM Neskey, P Katsonis, AA Patel, AM Ward, TK Hsu, ... Cancer research 75 (7), 1205-1215, 2015 | 99 | 2015 |
| Separation of Recombination and SOS Response in Escherichia coli RecA Suggests LexA Interaction Sites AK Adikesavan, P Katsonis, DC Marciano, R Lua, C Herman, O Lichtarge PLoS genetics 7 (9), e1002244, 2011 | 96 | 2011 |
| Desmosterolosis—phenotypic and molecular characterization of a third case and review of the literature CP Schaaf, J Koster, P Katsonis, L Kratz, OA Shchelochkov, F Scaglia, ... American journal of medical genetics Part A 155 (7), 1597-1604, 2011 | 66 | 2011 |
| Molecular defects in human carbamoy phosphate synthetase I: mutational spectrum, diagnostic and protein structure considerations J Häberle, OA Shchelochkov, J Wang, P Katsonis, L Hall, S Reiss, A Eeds, ... Human mutation 32 (6), 579-589, 2011 | 64 | 2011 |
| Specific TP53 mutants overrepresented in ovarian cancer impact CNV, TP53 activity, responses to nutlin-3a, and cell survival LK Mullany, KK Wong, DC Marciano, P Katsonis, ER King-Crane, YA Ren, ... Neoplasia 17 (10), 789-803, 2015 | 62 | 2015 |
| Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer A Nair, HC Chung, T Sun, S Tyagi, LE Dobrolecki, R Dominguez-Vidana, ... Nature medicine 24 (4), 505-511, 2018 | 61 | 2018 |
| Genome interpretation using in silico predictors of variant impact P Katsonis, K Wilhelm, A Williams, O Lichtarge Human genetics 141 (10), 1549-1577, 2022 | 59 | 2022 |
| Comprehensive genomic characterization of parathyroid cancer identifies novel candidate driver mutations and core pathways CN Clarke, P Katsonis, TK Hsu, AM Koire, A Silva-Figueroa, I Christakis, ... Journal of the Endocrine Society 3 (3), 544-559, 2019 | 59 | 2019 |
| Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain‐of‐function mutant p53R172H Z Li, CL Gonzalez, B Wang, Y Zhang, O Mejia, P Katsonis, O Lichtarge, ... The Journal of pathology 240 (2), 224-234, 2016 | 56 | 2016 |
| Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease JP Lees-Miller, A Cobban, P Katsonis, A Bacolla, SE Tsutakawa, ... Progress in biophysics and molecular biology 163, 87-108, 2021 | 55 | 2021 |
| Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly (ADP-ribose) glycohydrolase (PARG) structures with inhibitors CA Brosey, JH Houl, P Katsonis, LPF Balapiti-Modarage, S Bommagani, ... Progress in Biophysics and Molecular Biology 163, 171-186, 2021 | 53 | 2021 |
| Prediction and redesign of protein–protein interactions RC Lua, DC Marciano, P Katsonis, AK Adikesavan, AD Wilkins, ... Progress in biophysics and molecular biology 116 (2-3), 194-202, 2014 | 39 | 2014 |
