| Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis W Lee, RJ Nims, A Savadipour, Q Zhang, HA Leddy, F Liu, AL McNulty, ... Proceedings of the National Academy of Sciences 118 (13), 2021 | 179 | 2021 |
| A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues RJ Nims, L Pferdehirt, NB Ho, A Savadipour, J Lorentz, S Sohi, J Kassab, ... Science Advances 7 (5), eabd9858, 2021 | 76 | 2021 |
| The Balance between Actomyosin Contractility and Microtubule Polymerization Regulates Hierarchical Protrusions That Govern Efficient Fibroblast-Collagen Interactions D Shakiba, F Alisafaei, A Savadipour, RA Rowe, Z Liu, KM Pryse, ... ACS nano, 2020 | 50 | 2020 |
| Single‐cell RNA sequencing reveals the induction of novel myeloid and myeloid‐associated cell populations in visceral fat with long‐term obesity NS Harasymowicz, N Rashidi, A Savadipour, CL Wu, R Tang, J Bramley, ... The FASEB Journal 35 (3), e21417, 2021 | 38 | 2021 |
| The Role of PIEZO Ion Channels in the Musculoskeletal System A Savadipour, D Palmer, EV Ely, KH Collins, JM Garcia-Castorena, ... American Journal of Physiology-Cell Physiology, 2023 | 36 | 2023 |
| Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels A Savadipour, RJ Nims, DB Katz, F Guilak Connective Tissue Research, 1-13, 2021 | 36 | 2021 |
| Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes. A Savadipour, RJ Nims, N Rashidi, JM Garcia-Castorena, R Tang, ... Proceedings of the National Academy of Sciences of the United States of …, 2023 | 30 | 2023 |
| Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes AR Dicks, GI Maksaev, Z Harissa, A Savadipour, R Tang, N Steward, ... Elife 12, e71154, 2023 | 20 | 2023 |
| Modulation of TRPV4 protects against degeneration induced by sustained loading and promotes matrix synthesis in the intervertebral disc GWD Easson, A Savadipour, A Anandarajah, LE Iannucci, SP Lake, ... FASEB journal: official publication of the Federation of American Societies …, 2023 | 14 | 2023 |
| Hydrogel Encapsulation of Genome-Engineered Stem Cells for Long-Term Self-Regulating Anti-Cytokine Therapy KH Collins, L Pferdehirt, LS Saleh, A Savadipour, LE Springer, KL Lenz, ... Gels 9 (2), 169, 2023 | 13 | 2023 |
| An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties DB Katz, NPT Huynh, A Savadipour, I Palte, F Guilak Biochemical and Biophysical Research Communications 530 (1), 252-258, 2020 | 11 | 2020 |
| TRPV4 differentially controls inflammatory cytokine networks during static and dynamic compression of the intervertebral disc GWD Easson, A Savadipour, C Gonzalez, F Guilak, SY Tang JOR Spine, e1282, 2023 | 8 | 2023 |
| Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feed-forward … W Lee, RJ Nims, A Savadipour, H Leddy, F Liu, A McNulty, Y Chen, ... bioRxiv, 2020.05. 23.112565, 2020 | 2 | 2020 |
| Mechanosensitive Ion Channels as Therapeutics Targets for Osteoarthritis A Savadipour | 1 | 2023 |
| Polyunsaturated fatty acids suppress PIEZO ion channel mechanotransduction in articular chondrocytes GK Marushack, A Savadipour, R Tang, JM Garcia‐Castorena, N Rashidi, ... The FASEB Journal 39 (1), e70290, 2025 | | 2025 |
| PIEZO1-Mediated Mechanotransduction Regulates Collagen Synthesis on Nanostructured 2D and 3D Models of Fibrosis N Rashidi, NS Harasymowicz, A Savadipour, N Steward, R Tang, ... Acta Biomaterialia, 2024 | | 2024 |
| CONDITIONAL DELETION OF TRANSIENT RECEPTOR POTENTIAL VANILLOID 4 (TRPV4) IN THE INTERVERTEBRAL DISC EXACERBATES INJURY-INDUCED DEGENERATION G Easson, SW Clayton, RE Walk, A Savadipour, F Guilak, S Tang Osteoarthritis and Cartilage 32, S104, 2024 | | 2024 |
| Maternal high‐fat high‐sugar diet impairs bone quality and strength but not cartilage in aging mice AK Oestreich, NS Harasymowicz, A Savadipour, Z Harissa, N Rashidi, ... Journal of Orthopaedic Research®, 0 | | |
Farshid GuilakOrthopaedic Surgery, Washington University; Shriners Hospitals for ChildrenAdresse e-mail validée de wustl.edu