Measuring biological age using omics data J Rutledge, H Oh, T Wyss-Coray Nature Reviews Genetics 23 (12), 715-727, 2022 | 298 | 2022 |
Organ aging signatures in the plasma proteome track health and disease HSH Oh, J Rutledge, D Nachun, R Pálovics, O Abiose, P Moran-Losada, ... Nature 624 (7990), 164-172, 2023 | 189 | 2023 |
Genetically programmable self‐regenerating bacterial hydrogels AM Duraj‐Thatte, NMD Courchesne, P Praveschotinunt, J Rutledge, ... Advanced Materials 31 (40), 1901826, 2019 | 134 | 2019 |
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment N Piehl, L van Olst, A Ramakrishnan, V Teregulova, B Simonton, Z Zhang, ... Cell 185 (26), 5028-5039. e13, 2022 | 100 | 2022 |
Programmable microbial ink for 3D printing of living materials produced from genetically engineered protein nanofibers AM Duraj-Thatte, A Manjula-Basavanna, J Rutledge, J Xia, S Hassan, ... Nature Communications 12 (1), 6600, 2021 | 94 | 2021 |
Limited proteolysis–mass spectrometry reveals aging-associated changes in cerebrospinal fluid protein abundances and structures SR Shuken, J Rutledge, T Iram, PM Losada, EN Wilson, KI Andreasson, ... Nature Aging 2 (5), 379-388, 2022 | 39 | 2022 |
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease YJ Sung, C Yang, J Norton, M Johnson, A Fagan, RJ Bateman, RJ Perrin, ... Science translational medicine 15 (703), eabq5923, 2023 | 36 | 2023 |
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer’s disease C Cruchaga, D Western, J Timsina, L Wang, C Wang, C Yang, M Ali, ... Research square, 2023 | 29 | 2023 |
Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics Z He, Y Le Guen, L Liu, J Lee, S Ma, AC Yang, X Liu, J Rutledge, ... The American Journal of Human Genetics 108 (12), 2336-2353, 2021 | 23 | 2021 |
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease J Rutledge, B Lehallier, P Zarifkar, PM Losada, M Shahid-Besanti, ... Acta Neuropathologica 147 (1), 52, 2024 | 22 | 2024 |
Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer’s disease L Wang, NP Nykänen, D Western, P Gorijala, J Timsina, F Li, Z Wang, ... Molecular neurodegeneration 19 (1), 1, 2024 | 16 | 2024 |
Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease. C Cruchaga, M Ali, Y Shen, A Do, L Wang, D Western, M Liu, A Beric, ... Research Square, 2024 | 6 | 2024 |
Disagreement on foundational principles of biological aging VN Gladyshev, B Anderson, H Barlit, B Barré, S Beck, B Behrouz, ... PNAS nexus 3 (12), pgae499, 2024 | 4 | 2024 |
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease D Western, J Timsina, L Wang, C Wang, C Yang, B Phillips, Y Wang, ... Nature Genetics, 1-13, 2024 | 3 | 2024 |
Post‐translational modifications linked to preclinical Alzheimer's disease–related pathological and cognitive changes O Abiose, J Rutledge, P Moran‐Losada, ME Belloy, EN Wilson, Z He, ... Alzheimer's & Dementia 20 (3), 1851-1867, 2024 | 2 | 2024 |
Plasma proteomics in the UK Biobank reveals youthful brains and immune systems promote healthspan and longevity HSH Oh, Y Le Guen, N Rappoport, DY Urey, J Rutledge, A Brunet, ... bioRxiv, 2024.06. 07.597771, 2024 | 2 | 2024 |
Aromatic L-Amino Acid Decarboxylase is a novel fluid biomarker of Parkinson’s disease J Rutledge, B Lehallier, P Zarifkar, PM Losada, S Ryman, M Yutsis, ... medRxiv, 2022.11. 09.22282149, 2022 | 1 | 2022 |
Publisher Correction: Limited proteolysis-mass spectrometry reveals aging-associated changes in cerebrospinal fluid protein abundances and structures SR Shuken, J Rutledge, T Iram, PM Losada, EN Wilson, KI Andreasson, ... Nature aging 2 (5), 455, 2022 | 1 | 2022 |
Hydrogels: Genetically Programmable Self‐Regenerating Bacterial Hydrogels (Adv. Mater. 40/2019) AM Duraj‐Thatte, NMD Courchesne, P Praveschotinunt, J Rutledge, ... Advanced Materials 31 (40), 1970289, 2019 | 1 | 2019 |
Multi‐cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease M Ali, J Timsina, Y Shen, A Do, L Wang, D Western, E Liu, A Beric, G Heo, ... Alzheimer's & Dementia 20 (Suppl 2), e084185, 2025 | | 2025 |