Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury Z Álvarez, AN Kolberg-Edelbrock, IR Sasselli, JA Ortega, R Qiu, ... Science 374 (6569), 848-856, 2021 | 270 | 2021 |
BDNF/MAPK/ERK–Induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration JA Ortega, S Alcántara Cerebral cortex 20 (9), 2132-2144, 2010 | 89 | 2010 |
Nucleocytoplasmic proteomic analysis uncovers eRF1 and nonsense-mediated decay as modifiers of ALS/FTD C9orf72 toxicity JA Ortega, EL Daley, S Kour, M Samani, L Tellez, HS Smith, EA Hall, ... Neuron 106 (1), 90-107. e13, 2020 | 81 | 2020 |
Dissecting the functional consequences of de novo DNA methylation dynamics in human motor neuron differentiation and physiology MJ Ziller, JA Ortega, KA Quinlan, DP Santos, H Gu, EJ Martin, C Galonska, ... Cell stem cell 22 (4), 559-574. e9, 2018 | 76 | 2018 |
Inducing functional radial glia-like progenitors from cortical astrocyte cultures using micropatterned PMMA M Mattotti, Z Alvarez, JA Ortega, JA Planell, E Engel, S Alcántara Biomaterials 33 (6), 1759-1770, 2012 | 74 | 2012 |
All-optical electrophysiology for high-throughput functional characterization of a human iPSC-derived motor neuron model of ALS E Kiskinis, JM Kralj, P Zou, EN Weinstein, H Zhang, K Tsioras, O Wiskow, ... Stem cell reports 10 (6), 1991-2004, 2018 | 65 | 2018 |
Sonic hedgehog promotes generation and maintenance of human forebrain Olig2 progenitors JA Ortega, NV Radonjić, N Zecevic Frontiers in cellular neuroscience 7, 254, 2013 | 59 | 2013 |
AMPA-kainate receptor inhibition promotes neurologic recovery in premature rabbits with intraventricular hemorrhage P Dohare, MT Zia, E Ahmed, A Ahmed, V Yadala, AL Schober, JA Ortega, ... Journal of Neuroscience 36 (11), 3363-3377, 2016 | 52 | 2016 |
Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons Z Álvarez, JA Ortega, K Sato, IR Sasselli, AN Kolberg-Edelbrock, R Qiu, ... Cell stem cell 30 (2), 219-238. e14, 2023 | 49 | 2023 |
Oxygen levels regulate the development of human cortical radial glia cells JA Ortega, CL Sirois, F Memi, N Glidden, N Zecevic Cerebral Cortex 27 (7), 3736-3751, 2017 | 44 | 2017 |
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility AM Gleixner, BM Verdone, CG Otte, EN Anderson, N Ramesh, ... Nature communications 13 (1), 3380, 2022 | 43 | 2022 |
The subventricular zone: a key player in human neocortical development JA Ortega, F Memi, N Radonjic, R Filipovic, I Bagasrawala, N Zecevic, ... The Neuroscientist 24 (2), 156-170, 2018 | 38 | 2018 |
Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy D Simkin, KA Marshall, CG Vanoye, RR Desai, BI Bustos, BN Piyevsky, ... Elife 10, e64434, 2021 | 36 | 2021 |
Learning and memory disabilities in IUGR babies: Functional and molecular analysis in a rat model M Camprubi Camprubi, R Balada Caballe, JA Ortega Cano, ... Brain and Behavior 7 (3), e00631, 2017 | 32 | 2017 |
The role of sonic hedgehog in the specification of human cortical progenitors in vitro NV Radonjić, F Memi, JA Ortega, N Glidden, H Zhan, N Zecevic Cerebral Cortex 26 (1), 131-143, 2016 | 28 | 2016 |
The complexity of the calretinin-expressing progenitors in the human cerebral cortex NV Radonjić, JA Ortega, F Memi, K Dionne, I Jakovcevski, N Zecevic Frontiers in neuroanatomy 8, 82, 2014 | 26 | 2014 |
Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation C Sánchez‐Camacho, JA Ortega, I Ocana, S Alcántara, P Bovolenta Developmental Neurobiology 71 (5), 337-350, 2011 | 24 | 2011 |
Botulinum toxin conditioning enhances motor axon regeneration in mouse and human preclinical models CK Franz, A Puritz, LA Jordan, J Chow, JA Ortega, E Kiskinis, ... Neurorehabilitation and neural repair 32 (8), 735-745, 2018 | 18 | 2018 |
Apoptotic and anti-proliferative effects of all-trans retinoic acid.: Adenine nucleotide translocase sensitizes HeLa cells to all-trans retinoic acid M Zamora, JA Ortega, L Alaña, O Viñas, T Mampel Experimental cell research 312 (10), 1813-1819, 2006 | 15 | 2006 |
Enhanced neuron growth and electrical activity by a supramolecular netrin-1 mimetic nanofiber CS Smith, Z Álvarez, R Qiu, IR Sasselli, T Clemons, JA Ortega, ... ACS nano 17 (20), 19887-19902, 2023 | 10 | 2023 |