| Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model SA Tersey, Y Nishiki, AT Templin, SM Cabrera, ND Stull, SC Colvin, ... Diabetes 61 (4), 818-827, 2012 | 372 | 2012 |
| Regulation of the pancreatic pro-endocrine gene neurogenin3 JC Lee, SB Smith, H Watada, J Lin, D Scheel, J Wang, RG Mirmira, ... Diabetes 50 (5), 928-936, 2001 | 350 | 2001 |
| Quantitative Assessment of Gene Targeting in Vitroand in Vivo by the Pancreatic Transcription Factor, Pdx1: IMPORTANCE OF CHROMATIN STRUCTURE IN DIRECTING PROMOTER BINDING∗ SK Chakrabarti, JC James, RG Mirmira Journal of Biological Chemistry 277 (15), 13286-13293, 2002 | 344 | 2002 |
| Restructuring of the gut microbiome by intermittent fasting prevents retinopathy and prolongs survival in db/db mice E Beli, Y Yan, L Moldovan, CP Vieira, R Gao, Y Duan, R Prasad, ... Diabetes 67 (9), 1867-1879, 2018 | 327 | 2018 |
| Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress MM Sachdeva, KC Claiborn, C Khoo, J Yang, DN Groff, RG Mirmira, ... Proceedings of the National Academy of Sciences 106 (45), 19090-19095, 2009 | 254 | 2009 |
| The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter K Ohneda, RG Mirmira, J Wang, JD Johnson, MS German Molecular and cellular biology, 2000 | 251 | 2000 |
| The Nkx6. 1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells JC Schisler, PB Jensen, DG Taylor, TC Becker, FK Knop, S Takekawa, ... Proceedings of the National Academy of Sciences 102 (20), 7297-7302, 2005 | 212 | 2005 |
| An acetate-specific GPCR, FFAR2, regulates insulin secretion M Priyadarshini, SR Villa, M Fuller, B Wicksteed, CR Mackay, T Alquier, ... Molecular endocrinology 29 (7), 1055-1066, 2015 | 201 | 2015 |
| The Roles of ATF3, an Adaptive-Response Gene, in High-Fat-Diet-Induced Diabetes and Pancreatic β-Cell Dysfunction EJ Zmuda, L Qi, MX Zhu, RG Mirmira, MR Montminy, T Hai Molecular Endocrinology 24 (7), 1423-1433, 2010 | 195 | 2010 |
| An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic β cells JM Sturek, JD Castle, AP Trace, LC Page, AM Castle, C Evans-Molina, ... The Journal of clinical investigation 120 (7), 2575-2589, 2010 | 190 | 2010 |
| Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic β cells SK Chakrabarti, J Francis, SM Ziesmann, JC Garmey, RG Mirmira Journal of Biological Chemistry 278 (26), 23617-23623, 2003 | 188 | 2003 |
| Proendocrine genes coordinate the pancreatic islet differentiation program in vitro R Gasa, C Mrejen, N Leachman, M Otten, M Barnes, J Wang, ... Proceedings of the National Academy of Sciences 101 (36), 13245-13250, 2004 | 187 | 2004 |
| The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice B Maier, T Ogihara, AP Trace, SA Tersey, RD Robbins, SK Chakrabarti, ... The Journal of clinical investigation 120 (6), 2156-2170, 2010 | 182 | 2010 |
| Transcription factors direct the development and function of pancreatic β cells SK Chakrabarti, RG Mirmira Trends in Endocrinology & Metabolism 14 (2), 78-84, 2003 | 168 | 2003 |
| Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice I Casimiro, ND Stull, SA Tersey, RG Mirmira Journal of Diabetes and its Complications 35 (2), 107795, 2021 | 166 | 2021 |
| Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing M Blandino-Rosano, R Barbaresso, M Jimenez-Palomares, N Bozadjieva, ... Nature communications 8 (1), 16014, 2017 | 162 | 2017 |
| Our response to COVID-19 as endocrinologists and diabetologists UB Kaiser, RG Mirmira, PM Stewart The Journal of clinical endocrinology & metabolism 105 (5), 1299-1301, 2020 | 159 | 2020 |
| Peroxisome proliferator-activated receptor γ activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of … C Evans-Molina, RD Robbins, T Kono, SA Tersey, GL Vestermark, ... Molecular and cellular biology, 2009 | 158 | 2009 |
| Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of … T Iype, J Francis, JC Garmey, JC Schisler, R Nesher, GC Weir, TC Becker, ... Journal of Biological Chemistry 280 (17), 16798-16807, 2005 | 158 | 2005 |
| Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes TG Deering, T Ogihara, AP Trace, B Maier, RG Mirmira Diabetes 58 (1), 185-193, 2009 | 151 | 2009 |
Sarah TerseyUniversity of ChicagoAdresse e-mail validée de uchicago.edu