A Dominant-Negative GFI1B Mutation in the Gray Platelet Syndrome D Monteferrario, NA Bolar, AE Marneth, KM Hebeda, SM Bergevoet, ... New England Journal of Medicine 370 (3), 245-253, 2014 | 182 | 2014 |
MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia KHM Prange, A Mandoli, T Kuznetsova, SY Wang, AM Sotoca, ... Oncogene 36 (23), 3346-3356, 2017 | 120 | 2017 |
Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders JM Bastida, ML Lozano, R Benito, K Janusz, V Palma-Barqueros, ... haematologica 103 (1), 148, 2017 | 119 | 2017 |
The molecular genetics of myeloproliferative neoplasms AE Marneth, A Mullally Cold Spring Harbor perspectives in medicine 10 (2), a034876, 2020 | 57 | 2020 |
Mechanical checkpoint regulates monocyte differentiation in fibrotic niches KH Vining, AE Marneth, K Adu-Berchie, JM Grolman, CM Tringides, Y Liu, ... Nature materials 21 (8), 939-950, 2022 | 45 | 2022 |
The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy S Liu, AE Marneth, G Alexe, SR Walker, HI Gandler, DQ Ye, K Labella, ... Blood advances 2 (23), 3428-3442, 2018 | 35 | 2018 |
Platelet CD34 expression and α/δ-granule abnormalities in GFI1B- and RUNX1-related familial bleeding disorders AE Marneth, WL Van Heerde, KM Hebeda, BAP Laros-van Gorkom, ... Blood, The Journal of the American Society of Hematology 129 (12), 1733-1736, 2017 | 31 | 2017 |
Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets R van Oorschot, M Hansen, JM Koornneef, AE Marneth, SM Bergevoet, ... Haematologica 104 (7), 1460, 2019 | 28 | 2019 |
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine M Gigoux, MO Holmström, R Zappasodi, JJ Park, S Pourpe, CC Bozkus, ... Science translational medicine 14 (649), eaba4380, 2022 | 18 | 2022 |
GFI136N as a therapeutic and prognostic marker for myelodysplastic syndrome L Botezatu, LC Michel, H Makishima, T Schroeder, U Germing, R Haas, ... Experimental hematology 44 (7), 590-595. e1, 2016 | 18 | 2016 |
GFI1 is required for RUNX1/ETO positive acute myeloid leukemia AE Marneth, L Botezatu, JM Hönes, JCL Israël, J Schütte, L Vassen, ... haematologica 103 (9), e395, 2018 | 17 | 2018 |
Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs JS Jutzi, AE Marneth, M Ciboddo, A Guerra-Moreno, MJ Jiménez-Santos, ... Blood, The Journal of the American Society of Hematology 140 (11), 1291-1304, 2022 | 14 | 2022 |
Augmenting emergency granulopoiesis with CpG conditioned mesenchymal stromal cells in murine neutropenic sepsis J Ng, F Guo, AE Marneth, S Ghanta, MY Kwon, J Keegan, X Liu, KT Wright, ... Blood Advances 4 (19), 4965-4979, 2020 | 14 | 2020 |
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response JS Jutzi, AE Marneth, MJ Jiménez-Santos, J Hem, A Guerra-Moreno, ... Leukemia 37 (2), 359-369, 2023 | 11 | 2023 |
Specific proteome changes in platelets from individuals with GATA1-, GFI1B-, and RUNX1-linked bleeding disorders MGJM Van Bergen, AE Marneth, AJ Hoogendijk, FPJ Van Alphen, ... Blood, The Journal of the American Society of Hematology 138 (1), 86-90, 2021 | 11 | 2021 |
Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses R van Oorschot, AE Marneth, SM Bergevoet, MGJM van Bergen, ... haematologica 104 (6), e260, 2019 | 11 | 2019 |
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells J Ng, AE Marneth, A Griffith, D Younger, S Ghanta, A Jiao, G Willis, J Han, ... Journal of Innate Immunity 15 (1), 765-781, 2023 | 8 | 2023 |
C-terminal BRE overexpression in 11q23-rearranged and t (8; 16) acute myeloid leukemia is caused by intragenic transcription initiation AE Marneth, KHM Prange, ASA Al Hinai, SM Bergevoet, N Tesi, ... Leukemia 32 (3), 828-836, 2018 | 7 | 2018 |
Busy signal: platelet-derived growth factor activation in myelofibrosis AE Marneth, A Mullally Haematologica 105 (8), 1988, 2020 | 5 | 2020 |
Generation and characterization of a human iPSC line SANi005-A containing the gray platelet associated heterozygous mutation p. Q287* in GFI1B M Hansen, E Varga, T Wüst, C Mellink, AM van der Kevie-Kersemaekers, ... Stem Cell Research 25, 34-37, 2017 | 5 | 2017 |