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Anna Engelina Marneth
Anna Engelina Marneth
Post-doc, Brigham and Women's Hospital, Harvard Medical School
Adresse e-mail validée de bwh.harvard.edu
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A Dominant-Negative GFI1B Mutation in the Gray Platelet Syndrome
D Monteferrario, NA Bolar, AE Marneth, KM Hebeda, SM Bergevoet, ...
New England Journal of Medicine 370 (3), 245-253, 2014
1822014
MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia
KHM Prange, A Mandoli, T Kuznetsova, SY Wang, AM Sotoca, ...
Oncogene 36 (23), 3346-3356, 2017
1202017
Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders
JM Bastida, ML Lozano, R Benito, K Janusz, V Palma-Barqueros, ...
haematologica 103 (1), 148, 2017
1192017
The molecular genetics of myeloproliferative neoplasms
AE Marneth, A Mullally
Cold Spring Harbor perspectives in medicine 10 (2), a034876, 2020
572020
Mechanical checkpoint regulates monocyte differentiation in fibrotic niches
KH Vining, AE Marneth, K Adu-Berchie, JM Grolman, CM Tringides, Y Liu, ...
Nature materials 21 (8), 939-950, 2022
452022
The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy
S Liu, AE Marneth, G Alexe, SR Walker, HI Gandler, DQ Ye, K Labella, ...
Blood advances 2 (23), 3428-3442, 2018
352018
Platelet CD34 expression and α/δ-granule abnormalities in GFI1B- and RUNX1-related familial bleeding disorders
AE Marneth, WL Van Heerde, KM Hebeda, BAP Laros-van Gorkom, ...
Blood, The Journal of the American Society of Hematology 129 (12), 1733-1736, 2017
312017
Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets
R van Oorschot, M Hansen, JM Koornneef, AE Marneth, SM Bergevoet, ...
Haematologica 104 (7), 1460, 2019
282019
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine
M Gigoux, MO Holmström, R Zappasodi, JJ Park, S Pourpe, CC Bozkus, ...
Science translational medicine 14 (649), eaba4380, 2022
182022
GFI136N as a therapeutic and prognostic marker for myelodysplastic syndrome
L Botezatu, LC Michel, H Makishima, T Schroeder, U Germing, R Haas, ...
Experimental hematology 44 (7), 590-595. e1, 2016
182016
GFI1 is required for RUNX1/ETO positive acute myeloid leukemia
AE Marneth, L Botezatu, JM Hönes, JCL Israël, J Schütte, L Vassen, ...
haematologica 103 (9), e395, 2018
172018
Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs
JS Jutzi, AE Marneth, M Ciboddo, A Guerra-Moreno, MJ Jiménez-Santos, ...
Blood, The Journal of the American Society of Hematology 140 (11), 1291-1304, 2022
142022
Augmenting emergency granulopoiesis with CpG conditioned mesenchymal stromal cells in murine neutropenic sepsis
J Ng, F Guo, AE Marneth, S Ghanta, MY Kwon, J Keegan, X Liu, KT Wright, ...
Blood Advances 4 (19), 4965-4979, 2020
142020
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response
JS Jutzi, AE Marneth, MJ Jiménez-Santos, J Hem, A Guerra-Moreno, ...
Leukemia 37 (2), 359-369, 2023
112023
Specific proteome changes in platelets from individuals with GATA1-, GFI1B-, and RUNX1-linked bleeding disorders
MGJM Van Bergen, AE Marneth, AJ Hoogendijk, FPJ Van Alphen, ...
Blood, The Journal of the American Society of Hematology 138 (1), 86-90, 2021
112021
Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses
R van Oorschot, AE Marneth, SM Bergevoet, MGJM van Bergen, ...
haematologica 104 (6), e260, 2019
112019
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells
J Ng, AE Marneth, A Griffith, D Younger, S Ghanta, A Jiao, G Willis, J Han, ...
Journal of Innate Immunity 15 (1), 765-781, 2023
82023
C-terminal BRE overexpression in 11q23-rearranged and t (8; 16) acute myeloid leukemia is caused by intragenic transcription initiation
AE Marneth, KHM Prange, ASA Al Hinai, SM Bergevoet, N Tesi, ...
Leukemia 32 (3), 828-836, 2018
72018
Busy signal: platelet-derived growth factor activation in myelofibrosis
AE Marneth, A Mullally
Haematologica 105 (8), 1988, 2020
52020
Generation and characterization of a human iPSC line SANi005-A containing the gray platelet associated heterozygous mutation p. Q287* in GFI1B
M Hansen, E Varga, T Wüst, C Mellink, AM van der Kevie-Kersemaekers, ...
Stem Cell Research 25, 34-37, 2017
52017
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