| Structure and regulation of the human INO80–nucleosome complex R Ayala, O Willhoft, RJ Aramayo, M Wilkinson, EA McCormack, L Ocloo, ... Nature 556 (7701), 391-395, 2018 | 192 | 2018 |
| Structure and dynamics of the yeast SWR1-nucleosome complex O Willhoft, M Ghoneim, CL Lin, EYD Chua, M Wilkinson, Y Chaban, ... Science 362 (6411), eaat7716, 2018 | 170 | 2018 |
| Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis DJ Mole, SP Webster, I Uings, X Zheng, M Binnie, K Wilson, ... Nature medicine 22 (2), 202-209, 2016 | 155 | 2016 |
| Structure of the DNA-bound spacer capture complex of a type II CRISPR-Cas system M Wilkinson, G Drabavicius, A Silanskas, G Gasiunas, V Siksnys, ... Molecular cell 75 (1), 90-101. e5, 2019 | 68 | 2019 |
| A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair K Cheng, M Wilkinson, Y Chaban, DB Wigley Nature structural & molecular biology 27 (1), 71-77, 2020 | 67 | 2020 |
| Structural basis for translocation by AddAB helicase-nuclease and its arrest at [khgr] sites WW Krajewski, X Fu, M Wilkinson, NB Cronin, MS Dillingham, DB Wigley Nature 508 (7496), 416-419, 2014 | 54 | 2014 |
| Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones M Wilkinson, L Troman, WAK Wan Nur Ismah, Y Chaban, MB Avison, ... Elife 5, e22963, 2016 | 52 | 2016 |
| Mechanism for nuclease regulation in RecBCD M Wilkinson, Y Chaban, DB Wigley eLife 5, e18227, 2016 | 46 | 2016 |
| Structural evolution of fibril polymorphs during amyloid assembly M Wilkinson, Y Xu, D Thacker, AIP Taylor, DG Fisher, RU Gallardo, ... Cell 186 (26), 5798-5811. e26, 2023 | 32 | 2023 |
| The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain C Leistner, M Wilkinson, A Burgess, M Lovatt, S Goodbody, Y Xu, ... Nature Communications 14 (1), 2833, 2023 | 22 | 2023 |
| Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein EJ Byrd, M Wilkinson, SE Radford, F Sobott Journal of the American Society for Mass Spectrometry 34 (3), 493-504, 2023 | 19 | 2023 |
| Structural features of Chi recognition in AddAB with implications for RecBCD M Wilkinson, DB Wigley Cell Cycle 13 (18), 2812-2820, 2014 | 16 | 2014 |
| CryoET of β-amyloid and tau within postmortem Alzheimer’s disease brain MAG Gilbert, N Fatima, J Jenkins, TJ O’Sullivan, A Schertel, Y Halfon, ... Nature 631 (8022), 913-919, 2024 | 15 | 2024 |
| Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub M Wilkinson, OJ Wilkinson, C Feyerherm, EE Fletcher, DB Wigley, ... Elife 11, e83409, 2022 | 15 | 2022 |
| Disease-relevant β2-microglobulin variants share a common amyloid fold M Wilkinson, RU Gallardo, RM Martinez, N Guthertz, M So, LD Aubrey, ... Nature Communications 14 (1), 1190, 2023 | 14 | 2023 |
| Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination NS Gilhooly, C Carrasco, B Gollnick, M Wilkinson, DB Wigley, ... Nucleic acids research 44 (6), 2727-2741, 2016 | 7 | 2016 |
| Local structural preferences in shaping tau amyloid polymorphism N Louros, M Wilkinson, G Tsaka, M Ramakers, C Morelli, T Garcia, ... Nature Communications 15 (1), 1028, 2024 | 6 | 2024 |
| Structural dynamics and ligand binding in kynurenine-3-monooxygenase M Wilkinson The University of Edinburgh, 2013 | 6 | 2013 |
| Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid LD Aubrey, N Ninkina, SM Ulamec, NY Abramycheva, E Vasili, ... Proceedings of the National Academy of Sciences 121 (2), e2309700120, 2024 | 5 | 2024 |
| Residues 2 to 7 of α-synuclein regulate amyloid formation via lipid-dependent and lipid-independent pathways KM Dewison, B Rowlinson, JM Machin, JA Crossley, D Thacker, ... Proceedings of the National Academy of Sciences 121 (34), e2315006121, 2024 | 2 | 2024 |
Dale WigleyAdresse e-mail validée de imperial.ac.uk