Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants EF McDonald, CMP Sabusap, M Kim, L Plate Molecular Biology of the Cell 33 (7), ar62, 2022 | 27 | 2022 |
Structural Comparative Modeling of Multi-Domain F508del CFTR EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler Biomolecules 12 (3), 471, 2022 | 17 | 2022 |
Elexacaftor/VX-445–mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics M Kim, EF McDonald, CMP Sabusap, B Timalsina, D Joshi, JS Hong, ... Journal of Biological Chemistry 299 (10), 105242, 2023 | 15 | 2023 |
Structure activity relationship exploration of 5-hydroxy-2-(3-phenylpropyl) chromones as a unique 5-HT2B receptor antagonist scaffold M Kim, M Truss, PP Pagare, MA Essandoh, Y Zhang, DA Williams Bioorganic & Medicinal Chemistry Letters 30 (21), 127511, 2020 | 6 | 2020 |
Cystic Fibrosis Modulator Therapies: Bridging Insights from CF to other Membrane Protein Misfolding Diseases M Kim, L Plate Israel Journal of Chemistry, e202300152, 2024 | 3 | 2024 |
Evolving spectrum of adenosine deaminase (ADA) deficiency: Assessing genotype pathogenicity according to expressed ADA activity of 46 variants I Santisteban, FX Arredondo-Vega, P Bali, B Dalgic, HH Lee, M Kim, ... Journal of Allergy and Clinical Immunology 155 (1), 166-175, 2025 | 2 | 2025 |
Ribosomal frameshifting selectively modulates the biosynthesis, Assembly, and function of a misfolded CFTR variant P Carmody, FJ Roushar, A Tedman, M Herwig, M Kim, EF McDonald, ... bioRxiv, 2023.05. 02.539166, 2023 | 2 | 2023 |
Proteostasis Landscapes of Selective versus Poorly Responsive CFTR Variants Reveals Structural Vulnerabilities to Correction EF McDonald, M Kim, JA Olson III, J Meiler, L Plate bioRxiv, 2024 | 1 | 2024 |
Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant PJ Carmody, FJ Roushar, A Tedman, W Wang, M Herwig, M Kim, ... Proceedings of the National Academy of Sciences 121 (42), e2414768121, 2024 | | 2024 |
340 Off-target identification of cystic fibrosis pharmacological correctors using functionalized photocrosslinker analogs M Kim, K Kim, T Scaggs, G Sulikowski, A Naren, L Plate Journal of Cystic Fibrosis 23, S179, 2024 | | 2024 |
Proteostasis Landscapes of Cystic Fibrosis Variants Reveals Drug Response Vulnerability EF McDonald, M Kim, JA Olson III, J Meiler, L Plate bioRxiv, 2024.07. 10.602964, 2024 | | 2024 |
648 Distinct proteostasis and structural states drive VX-809 susceptibility of cystic fibrosis transmembrane conductance regulator mutants E McDonald, C Sabusap, M Kim, J Meiler, L Plate Journal of Cystic Fibrosis 21, S355-S356, 2022 | | 2022 |
Structural Comparative Modeling of Multi-Domain F508del CFTR. Biomolecules 2022, 12, 471 EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022 | | 2022 |
Structural comparative modeling of multi-domain ΔF508 CFTR EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler bioRxiv, 2021.11. 17.468921, 2021 | | 2021 |
623: Elexacaftor/VX-445-mediated CFTR interactomic remodeling of misfolding mutations M Kim, C Sabusap, E McDonald, D Joshi, J Hong, A Rab, E Sorscher, ... Journal of Cystic Fibrosis 20, S296, 2021 | | 2021 |
IDENTIFICATION OF CFTR PROTEOSTASIS PROFILES REGULATING PHARMACOLOGIC RESCUE OF PROTEIN MISFOLDING MUTATIONS CP Sabusap, M Kim, E McDonald, L Plate PEDIATRIC PULMONOLOGY 55, S72-S72, 2020 | | 2020 |
Design, synthesis, and evaluation of 5-hydroxy-2-(3-phenylpropyl) chromone derivatives as 5-HT2B receptor ligands MS Kim, M Truss, V Plascencia, H Wang, S Zaidi, Y Zhang, D Williams ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Design, Synthesis and Biological Evaluation of 5-Hydroxy-2-(3-phenylpropyl) Chromone Derivatives as 5-HT28 Receptor Ligands MS Kim Kalamazoo College, 2018 | | 2018 |