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Minsoo Kim
Minsoo Kim
Adresse e-mail validée de vanderbilt.edu
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Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants
EF McDonald, CMP Sabusap, M Kim, L Plate
Molecular Biology of the Cell 33 (7), ar62, 2022
272022
Structural Comparative Modeling of Multi-Domain F508del CFTR
EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler
Biomolecules 12 (3), 471, 2022
172022
Elexacaftor/VX-445–mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics
M Kim, EF McDonald, CMP Sabusap, B Timalsina, D Joshi, JS Hong, ...
Journal of Biological Chemistry 299 (10), 105242, 2023
152023
Structure activity relationship exploration of 5-hydroxy-2-(3-phenylpropyl) chromones as a unique 5-HT2B receptor antagonist scaffold
M Kim, M Truss, PP Pagare, MA Essandoh, Y Zhang, DA Williams
Bioorganic & Medicinal Chemistry Letters 30 (21), 127511, 2020
62020
Cystic Fibrosis Modulator Therapies: Bridging Insights from CF to other Membrane Protein Misfolding Diseases
M Kim, L Plate
Israel Journal of Chemistry, e202300152, 2024
32024
Evolving spectrum of adenosine deaminase (ADA) deficiency: Assessing genotype pathogenicity according to expressed ADA activity of 46 variants
I Santisteban, FX Arredondo-Vega, P Bali, B Dalgic, HH Lee, M Kim, ...
Journal of Allergy and Clinical Immunology 155 (1), 166-175, 2025
22025
Ribosomal frameshifting selectively modulates the biosynthesis, Assembly, and function of a misfolded CFTR variant
P Carmody, FJ Roushar, A Tedman, M Herwig, M Kim, EF McDonald, ...
bioRxiv, 2023.05. 02.539166, 2023
22023
Proteostasis Landscapes of Selective versus Poorly Responsive CFTR Variants Reveals Structural Vulnerabilities to Correction
EF McDonald, M Kim, JA Olson III, J Meiler, L Plate
bioRxiv, 2024
12024
Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant
PJ Carmody, FJ Roushar, A Tedman, W Wang, M Herwig, M Kim, ...
Proceedings of the National Academy of Sciences 121 (42), e2414768121, 2024
2024
340 Off-target identification of cystic fibrosis pharmacological correctors using functionalized photocrosslinker analogs
M Kim, K Kim, T Scaggs, G Sulikowski, A Naren, L Plate
Journal of Cystic Fibrosis 23, S179, 2024
2024
Proteostasis Landscapes of Cystic Fibrosis Variants Reveals Drug Response Vulnerability
EF McDonald, M Kim, JA Olson III, J Meiler, L Plate
bioRxiv, 2024.07. 10.602964, 2024
2024
648 Distinct proteostasis and structural states drive VX-809 susceptibility of cystic fibrosis transmembrane conductance regulator mutants
E McDonald, C Sabusap, M Kim, J Meiler, L Plate
Journal of Cystic Fibrosis 21, S355-S356, 2022
2022
Structural Comparative Modeling of Multi-Domain F508del CFTR. Biomolecules 2022, 12, 471
EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022
2022
Structural comparative modeling of multi-domain ΔF508 CFTR
EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler
bioRxiv, 2021.11. 17.468921, 2021
2021
623: Elexacaftor/VX-445-mediated CFTR interactomic remodeling of misfolding mutations
M Kim, C Sabusap, E McDonald, D Joshi, J Hong, A Rab, E Sorscher, ...
Journal of Cystic Fibrosis 20, S296, 2021
2021
IDENTIFICATION OF CFTR PROTEOSTASIS PROFILES REGULATING PHARMACOLOGIC RESCUE OF PROTEIN MISFOLDING MUTATIONS
CP Sabusap, M Kim, E McDonald, L Plate
PEDIATRIC PULMONOLOGY 55, S72-S72, 2020
2020
Design, synthesis, and evaluation of 5-hydroxy-2-(3-phenylpropyl) chromone derivatives as 5-HT2B receptor ligands
MS Kim, M Truss, V Plascencia, H Wang, S Zaidi, Y Zhang, D Williams
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Design, Synthesis and Biological Evaluation of 5-Hydroxy-2-(3-phenylpropyl) Chromone Derivatives as 5-HT28 Receptor Ligands
MS Kim
Kalamazoo College, 2018
2018
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