The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 3276 | 2020 |
The impact of sex on gene expression across human tissues M Oliva, M Muñoz-Aguirre, S Kim-Hellmuth, V Wucher, ADH Gewirtz, ... Science 369 (6509), eaba3066, 2020 | 862 | 2020 |
A quantitative proteome map of the human body L Jiang, M Wang, S Lin, R Jian, X Li, J Chan, G Dong, H Fang, ... Cell 183 (1), 269-283. e19, 2020 | 369 | 2020 |
Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function G Eraslan, E Drokhlyansky, S Anand, E Fiskin, A Subramanian, M Slyper, ... Science 376 (6594), eabl4290, 2022 | 286 | 2022 |
A proteogenomic portrait of lung squamous cell carcinoma S Satpathy, K Krug, PMJ Beltran, SR Savage, F Petralia, C Kumar-Sinha, ... Cell 184 (16), 4348-4371. e40, 2021 | 263 | 2021 |
Scaling computational genomics to millions of individuals with GPUs A Taylor-Weiner, F Aguet, NJ Haradhvala, S Gosai, S Anand, J Kim, ... Genome biology 20, 1-5, 2019 | 181 | 2019 |
Genomic profiling of smoldering multiple myeloma identifies patients at a high risk of disease progression M Bustoros, R Sklavenitis-Pistofidis, J Park, R Redd, B Zhitomirsky, ... Journal of Clinical Oncology 38 (21), 2380-2389, 2020 | 172 | 2020 |
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease OM de Goede, DC Nachun, NM Ferraro, MJ Gloudemans, AS Rao, ... Cell 184 (10), 2633-2648. e19, 2021 | 145 | 2021 |
Transcriptomic signatures across human tissues identify functional rare genetic variation NM Ferraro, BJ Strober, J Einson, NS Abell, F Aguet, AN Barbeira, ... Science 369 (6509), eaaz5900, 2020 | 141 | 2020 |
Molecular map of chronic lymphocytic leukemia and its impact on outcome BA Knisbacher, Z Lin, CK Hahn, F Nadeu, M Duran-Ferrer, KE Stevenson, ... Nature genetics 54 (11), 1664-1674, 2022 | 109 | 2022 |
Proteogenomic data and resources for pan-cancer analysis Y Li, Y Dou, FDV Leprevost, Y Geffen, AP Calinawan, F Aguet, Y Akiyama, ... Cancer cell 41 (8), 1397-1406, 2023 | 77 | 2023 |
Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation Y Geffen, S Anand, Y Akiyama, TM Yaron, Y Song, JL Johnson, ... Cell 186 (18), 3945-3967. e26, 2023 | 64 | 2023 |
Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis R Boiarsky, NJ Haradhvala, JB Alberge, R Sklavenitis-Pistofidis, ... Nature Communications 13 (1), 7040, 2022 | 51 | 2022 |
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... Science signaling 15 (757), eabm0808, 2022 | 51 | 2022 |
Pan-cancer proteogenomics connects oncogenic drivers to functional states Y Li, E Porta-Pardo, C Tokheim, MH Bailey, TM Yaron, V Stathias, ... Cell 186 (18), 3921-3944. e25, 2023 | 50 | 2023 |
SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2 TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... | 40 | 2020 |
Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin WW Liang, RJH Lu, RG Jayasinghe, SM Foltz, E Porta-Pardo, Y Geffen, ... Cancer cell 41 (9), 1567-1585. e7, 2023 | 38 | 2023 |
Prediction of pKa Using Machine Learning Methods with Rooted Topological Torsion Fingerprints: Application to Aliphatic Amines Y Lu, S Anand, W Shirley, P Gedeck, BP Kelley, S Skolnik, S Rodde, ... Journal of chemical information and modeling 59 (11), 4706-4719, 2019 | 38 | 2019 |
Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma R Sklavenitis-Pistofidis, MP Aranha, RA Redd, J Baginska, ... Cancer Cell 40 (11), 1358-1373. e8, 2022 | 36 | 2022 |
The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... BioRxiv, 2020.08. 14.251207, 2020 | 36 | 2020 |