| Transcriptional regulatory code of a eukaryotic genome CT Harbison, DB Gordon, TI Lee, NJ Rinaldi, KD Macisaac, TW Danford, ... Nature 431 (7004), 99-104, 2004 | 2694 | 2004 |
| Foxp3 occupancy and regulation of key target genes during T-cell stimulation A Marson, K Kretschmer, GM Frampton, ES Jacobsen, JK Polansky, ... Nature 445 (7130), 931-935, 2007 | 979 | 2007 |
| An improved map of conserved regulatory sites for Saccharomyces cerevisiae KD MacIsaac, T Wang, DB Gordon, DK Gifford, GD Stormo, E Fraenkel BMC bioinformatics 7, 1-14, 2006 | 859 | 2006 |
| A quantitative atlas of polyadenylation in five mammals A Derti, P Garrett-Engele, KD MacIsaac, RC Stevens, S Sriram, R Chen, ... Genome research 22 (6), 1173-1183, 2012 | 740 | 2012 |
| Tissue-specific transcriptional regulation has diverged significantly between human and mouse DT Odom, RD Dowell, ES Jacobsen, W Gordon, TW Danford, ... Nature genetics 39 (6), 730-732, 2007 | 644 | 2007 |
| Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss H Liu, J Golji, LK Brodeur, FS Chung, JT Chen, RS deBeaumont, ... Nature medicine 25 (1), 95-102, 2019 | 303 | 2019 |
| Practical strategies for discovering regulatory DNA sequence motifs KD MacIsaac, E Fraenkel PLoS computational biology 2 (4), e36, 2006 | 214 | 2006 |
| FAP delineates heterogeneous and functionally divergent stromal cells in immune-excluded breast tumors V Cremasco, JL Astarita, AL Grauel, S Keerthivasan, K MacIsaac, ... Cancer immunology research 6 (12), 1472-1485, 2018 | 182 | 2018 |
| Genomic analysis of nasopharyngeal carcinoma reveals TME-based subtypes L Zhang, KD MacIsaac, T Zhou, PY Huang, C Xin, JR Dobson, K Yu, ... Molecular Cancer Research 15 (12), 1722-1732, 2017 | 161 | 2017 |
| Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development S Hartwig, J Ho, P Pandey, K MacIsaac, M Taglienti, M Xiang, G Alterovitz, ... Development 137 (7), 1189-1203, 2010 | 161 | 2010 |
| TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts AL Grauel, B Nguyen, D Ruddy, T Laszewski, S Schwartz, J Chang, ... Nature communications 11 (1), 6315, 2020 | 151 | 2020 |
| Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features JJ Pitt, M Riester, Y Zheng, TF Yoshimatsu, A Sanni, O Oluwasola, ... Nature communications 9 (1), 4181, 2018 | 107 | 2018 |
| High-resolution computational models of genome binding events Y Qi, A Rolfe, KD MacIsaac, GK Gerber, D Pokholok, J Zeitlinger, ... Nature biotechnology 24 (8), 963-970, 2006 | 107 | 2006 |
| A hypothesis-based approach for identifying the binding specificity of regulatory proteins from chromatin immunoprecipitation data KD MacIsaac, DB Gordon, L Nekludova, DT Odom, J Schreiber, ... Bioinformatics 22 (4), 423-429, 2006 | 102 | 2006 |
| Phenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus J Bai, SL Smock, GR Jackson Jr, KD MacIsaac, Y Huang, C Mankus, ... PloS one 10 (2), e0118286, 2015 | 81 | 2015 |
| A quantitative model of transcriptional regulation reveals the influence of binding location on expression KD MacIsaac, KA Lo, W Gordon, S Motola, T Mazor, E Fraenkel PLoS computational biology 6 (4), e1000773, 2010 | 81 | 2010 |
| Inhibition of RORγT skews TCRα gene rearrangement and limits T cell repertoire diversity Y Guo, KD MacIsaac, Y Chen, RJ Miller, R Jain, B Joyce-Shaikh, ... Cell reports 17 (12), 3206-3218, 2016 | 55 | 2016 |
| Pre-treatment whole blood gene expression is associated with 14-week response assessed by dynamic contrast enhanced magnetic resonance imaging in infliximab-treated rheumatoid … KD MacIsaac, R Baumgartner, J Kang, A Loboda, C Peterfy, J DiCarlo, ... PLoS One 9 (12), e113937, 2014 | 31 | 2014 |
| Stereochemical analysis of D-glucopyranosyl-sulfoxides via a combined NMR, molecular modeling and X-ray crystallographic approach PH Buist, B Behrouzian, KD MacIsaac, S Cassel, P Rollin, A Imberty, ... Tetrahedron: Asymmetry 10 (15), 2881-2889, 1999 | 20 | 1999 |
| Sequence analysis of chromatin immunoprecipitation data for transcription factors KD MacIsaac, E Fraenkel Computational Biology of Transcription Factor Binding, 179-193, 2010 | 8 | 2010 |
