| Protein-based peptide-bond formation by aminoacyl-tRNA protein transferase K Watanabe, Y Toh, K Suto, Y Shimizu, N Oka, T Wada, K Tomita Nature 449 (7164), 867-871, 2007 | 100 | 2007 |
| Mechanism for the definition of elongation and termination by the class II CCA‐adding enzyme Y Toh, D Takeshita, T Numata, S Fukai, O Nureki, K Tomita The EMBO journal 28 (21), 3353-3365, 2009 | 59 | 2009 |
| Initiation of RNA polymerization and polymerase encapsidation by a small dsRNA virus AM Collier, OL Lyytinen, YR Guo, Y Toh, MM Poranen, YJ Tao PLoS pathogens 12 (4), e1005523, 2016 | 53 | 2016 |
| Crystal structure of the human astrovirus capsid protein Y Toh, J Harper, KA Dryden, M Yeager, CF Arias, E Méndez, YJ Tao Journal of virology 90 (20), 9008-9017, 2016 | 46 | 2016 |
| Unlike LGR4, LGR5 potentiates Wnt–β-catenin signaling without sequestering E3 ligases S Park, L Wu, J Tu, W Yu, Y Toh, KS Carmon, QJ Liu Science signaling 13 (660), eaaz4051, 2020 | 34 | 2020 |
| Crystal structure of an orthomyxovirus matrix protein reveals mechanisms for self-polymerization and membrane association W Zhang, W Zheng, Y Toh, MA Betancourt-Solis, J Tu, Y Fan, ... Proceedings of the National Academy of Sciences 114 (32), 8550-8555, 2017 | 28 | 2017 |
| Molecular basis for maintenance of fidelity during the CCA‐adding reaction by a CCA‐adding enzyme Y Toh, T Numata, K Watanabe, D Takeshita, O Nureki, K Tomita The EMBO Journal 27 (14), 1944-1952, 2008 | 27 | 2008 |
| Mechanism for the alteration of the substrate specificities of template-independent RNA polymerases Y Toh, D Takeshita, T Nagaike, T Numata, K Tomita Structure 19 (2), 232-243, 2011 | 24 | 2011 |
| Drug conjugates of antagonistic R-spondin 4 mutant for simultaneous targeting of Leucine-rich repeat-containing G protein-coupled receptors 4/5/6 for cancer treatment J Cui, Y Toh, S Park, W Yu, J Tu, L Wu, L Li, J Jacob, S Pan, KS Carmon, ... Journal of Medicinal Chemistry 64 (17), 12572-12581, 2021 | 10 | 2021 |
| LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands Y Toh, L Wu, S Park, A Wang, J Tu, W Yu, M Zuo, KS Carmon, QJ Liu Scientific Reports 13 (1), 10796, 2023 | 8 | 2023 |
| Transfer RNA synthesis and regulation Y Toh, H Hori, K Tomita, T Ueda, K Watanabe eLS, 2001 | 6 | 2001 |
| Transfer RNA synthesis and regulation H Hori, C Tomikawa, A Hirata, Y Toh, K Tomita, T Ueda, K Watanabe eLS, 2014 | 4 | 2014 |
| Drug Conjugates of Antagonistic RSPO4 Mutant For Simultaneous Targeting of LGR4/5/6 for Cancer Treatment J Cui, Y Toh, S Park, W Yu, J Tu, L Wu, L Li, J Jacob, S Pan, KS Carmon, ... Journal of medicinal chemistry 64 (17), 12572, 2021 | 3 | 2021 |
| Anti-tumor activity of camptothecin analog conjugate of a RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer Y Toh, L Wu, J Tu, Z Liang, AM Aldana, JJ Wen, L Li, S Pan, RH Julie, ... bioRxiv, 2024.10. 08.616548, 2024 | | 2024 |
| Antitumor Activity of a Pyrrolobenzodiazepine Antibody–Drug Conjugate Targeting LGR5 in Preclinical Models of Neuroblastoma J Tu, Y Toh, AM Aldana, JJ Wen, L Wu, J Jacob, L Li, S Pan, KS Carmon, ... Pharmaceutics 16 (7), 943, 2024 | | 2024 |
| Abstract C098: Targeting high-expression LGR5 by an R-spondin-based peptibody-drug conjugate is efficacious against neuroblastoma Y Toh Molecular Cancer Therapeutics 22 (12_Supplement), C098-C098, 2023 | | 2023 |
| Molecular basis for peptide-bond formation by an aminoacyl-tRNA protein transferase K Watanabe, Y Toh, K Tomita Seikagaku 81 (4), 294-298, 2009 | | 2009 |
