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Kareem N Mohni
Kareem N Mohni
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The replication checkpoint prevents two types of fork collapse without regulating replisome stability
H Dungrawala, KL Rose, KP Bhat, KN Mohni, GG Glick, FB Couch, ...
Molecular cell 59 (6), 998-1010, 2015
4122015
HMCES maintains genome integrity by shielding abasic sites in single-strand DNA
KN Mohni, SR Wessel, R Zhao, AC Wojciechowski, JW Luzwick, ...
Cell 176 (1), 144-153. e13, 2019
1742019
ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency
KN Mohni, GM Kavanaugh, D Cortez
Cancer research 74 (10), 2835-2845, 2014
1482014
A synthetic lethal screen identifies DNA repair pathways that sensitize cancer cells to combined ATR inhibition and cisplatin treatments
KN Mohni, PS Thompson, JW Luzwick, GG Glick, CS Pendleton, ...
PloS one 10 (5), e0125482, 2015
1222015
Functional analysis of the replication fork proteome identifies BET proteins as PCNA regulators
SR Wessel, KN Mohni, JW Luzwick, H Dungrawala, D Cortez
Cell reports 28 (13), 3497-3509. e4, 2019
1152019
The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism
AJ Schumacher, KN Mohni, Y Kan, EA Hendrickson, JM Stark, SK Weller
Public Library of Science 8 (8), e1002862, 2012
1152012
Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link
PS Thompson, KM Amidon, KN Mohni, D Cortez, BF Eichman
Nature structural & molecular biology 26 (7), 613-618, 2019
822019
Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response
S Smith, N Reuven, KN Mohni, AJ Schumacher, SK Weller
Journal of virology 88 (17), 10146-10156, 2014
812014
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled
KN Mohni, CM Livingston, D Cortez, SK Weller
Journal of virology 84 (23), 12152-12164, 2010
782010
Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins
KN Mohni, AR Dee, S Smith, AJ Schumacher, SK Weller
Journal of virology 87 (1), 531-542, 2013
592013
DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication
KN Mohni, AS Mastrocola, P Bai, SK Weller, CD Heinen
Journal of virology 85 (23), 12241-12253, 2011
572011
Structural characterization of interaction between human ubiquitin-specific protease 7 and immediate-early protein ICP0 of herpes simplex virus-1
AK Pozhidaeva, KN Mohni, S Dhe-Paganon, CH Arrowsmith, SK Weller, ...
Journal of Biological Chemistry 290 (38), 22907-22918, 2015
472015
Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling
KN Mohni, S Smith, AR Dee, AJ Schumacher, SK Weller
PLoS pathogens 9 (10), e1003652, 2013
432013
An intrinsically disordered region of the DNA repair protein Nbs1 is a species-specific barrier to herpes simplex virus 1 in primates
DI Lou, ET Kim, NR Meyerson, NJ Pancholi, KN Mohni, D Enard, ...
Cell Host & Microbe 20 (2), 178-188, 2016
412016
Enhancer of rudimentary homolog affects the replication stress response through regulation of RNA processing
G Kavanaugh, R Zhao, Y Guo, KN Mohni, G Glick, ME Lacy, MS Hutson, ...
Molecular and cellular biology 35 (17), 2979-2990, 2015
322015
Influenza Virus Subpopulations: Exchange of Lethal H5N1 Virus NS for H1N1 Virus NS Triggers De Novo Generation of Defective-Interfering Particles and Enhances Interferon …
JM Ngunjiri, GM Buchek, KN Mohni, MJ Sekellick, PI Marcus
Journal of Interferon & Cytokine Research, 2012
282012
A whole genome RNAi screen identifies replication stress response genes
G Kavanaugh, F Ye, KN Mohni, JW Luzwick, G Glick, D Cortez
DNA repair 35, 55-62, 2015
222015
Lethal H5N1 influenza viruses are not resistant to interferon action in human, simian, porcine or chicken cells
JM Ngunjiri, KN Mohni, MJ Sekellick, S Schultz-Cherry, RG Webster, ...
Nature Medicine 18 (10), 1456-1457, 2012
132012
The herpes simplex virus alkaline nuclease is required to maintain replication fork progression
PJ Mullon, E Maldonado-Luevano, KPM Mehta, KN Mohni
Journal of Virology 98 (12), e01836-24, 2024
12024
Herpes simplex virus: manipulating DNA damage response pathways
SK Weller, AJ Schumacher, KN Mohni
The FASEB Journal 26, 932.2-932.2, 2012
12012
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