| Tackling the emerging threat of antifungal resistance to human health MC Fisher, A Alastruey-Izquierdo, J Berman, T Bicanic, EM Bignell, ... Nature reviews microbiology 20 (9), 557-571, 2022 | 719 | 2022 |
| Siderophore Biosynthesis But Not Reductive Iron Assimilation Is Essential for Aspergillus fumigatus Virulence M Schrettl, E Bignell, C Kragl, C Joechl, T Rogers, HN Arst Jr, K Haynes, ... The Journal of experimental medicine 200 (9), 1213-1219, 2004 | 573 | 2004 |
| Distinct roles for intra-and extracellular siderophores during Aspergillus fumigatus infection M Schrettl, E Bignell, C Kragl, Y Sabiha, O Loss, M Eisendle, A Wallner, ... PLoS pathogens 3 (9), e128, 2007 | 471 | 2007 |
| Ambient pH gene regulation in fungi: making connections MA Peñalva, J Tilburn, E Bignell, HN Arst Trends in microbiology 16 (6), 291-300, 2008 | 419 | 2008 |
| Sub-telomere directed gene expression during initiation of invasive aspergillosis A McDonagh, ND Fedorova, J Crabtree, Y Yu, S Kim, D Chen, O Loss, ... PLoS pathogens 4 (9), e1000154, 2008 | 281 | 2008 |
| Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA FM Soriani, I Malavazi, ME da Silva Ferreira, M Savoldi, ... Molecular microbiology 67 (6), 1274-1291, 2008 | 192 | 2008 |
| The Aspergillus fumigatus transcriptional activator CpcA contributes significantly to the virulence of this fungal pathogen S Krappmann, EM Bignell, U Reichard, T Rogers, K Haynes, GH Braus Molecular microbiology 52 (3), 785-799, 2004 | 174 | 2004 |
| The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis M Bertuzzi, M Schrettl, L Alcazar-Fuoli, TC Cairns, A Munoz, LA Walker, ... PLoS pathogens 10 (10), e1004413, 2014 | 168 | 2014 |
| The Aspergillus pH‐responsive transcription factor PacC regulates virulence E Bignell, S Negrete‐Urtasun, AM Calcagno, K Haynes, HN Arst Jr, ... Molecular microbiology 55 (4), 1072-1084, 2005 | 168 | 2005 |
| Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus S Yasmin, L Alcazar-Fuoli, M Gründlinger, T Puempel, T Cairns, M Blatzer, ... Proceedings of the National Academy of Sciences 109 (8), E497-E504, 2012 | 142 | 2012 |
| Two new genes involved in signalling ambient pH in Aspergillus nidulans HN Arst, E Bignell, J Tilburn Molecular and General Genetics MGG 245, 787-790, 1994 | 128 | 1994 |
| The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus T Furukawa, N Van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, ... Nature communications 11 (1), 427, 2020 | 119 | 2020 |
| Pathogenesis of respiratory viral and fungal coinfections F Salazar, E Bignell, GD Brown, PC Cook, A Warris Clinical Microbiology Reviews 35 (1), e00094-21, 2022 | 107 | 2022 |
| Specificity Determinants of Proteolytic Processing of Aspergillus PacC Transcription Factor Are Remote from the Processing Site, and Processing Occurs in Yeast If … JM Mingot, J Tilburn, E Diez, E Bignell, M Orejas, DA Widdick, S Sarkar, ... Molecular and cellular biology 19 (2), 1390-1400, 1999 | 106 | 1999 |
| Inactivation of Transcription Factor Gene ACE2 in the Fungal Pathogen Candida glabrata Results in Hypervirulence M Kamran, AM Calcagno, H Findon, E Bignell, MD Jones, P Warn, ... Eukaryotic cell 3 (2), 546-552, 2004 | 102 | 2004 |
| Secondary metabolite arsenal of an opportunistic pathogenic fungus E Bignell, TC Cairns, K Throckmorton, WC Nierman, NP Keller Philosophical Transactions of the Royal Society B: Biological Sciences 371 …, 2016 | 99 | 2016 |
| Candida glabrata STE12 is required for wild‐type levels of virulence and nitrogen starvation induced filamentation AM Calcagno, E Bignell, P Warn, MD Jones, DW Denning, ... Molecular microbiology 50 (4), 1309-1318, 2003 | 97 | 2003 |
| The effects of dsRNA mycoviruses on growth and murine virulence of Aspergillus fumigatus MF Bhatti, A Jamal, MA Petrou, TC Cairns, EM Bignell, RHA Coutts Fungal Genetics and Biology 48 (11), 1071-1075, 2011 | 87 | 2011 |
| A Regulator of Aspergillus fumigatus Extracellular Proteolytic Activity Is Dispensable for Virulence A Bergmann, T Hartmann, T Cairns, EM Bignell, S Krappmann Infection and immunity 77 (9), 4041-4050, 2009 | 86 | 2009 |
| On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction EA Espeso, T Roncal, E Díez, L Rainbow, E Bignell, J Álvaro, T Suárez, ... The EMBO journal, 2000 | 86 | 2000 |
