| Addiction as a stress surfeit disorder GF Koob, CL Buck, A Cohen, S Edwards, PE Park, JE Schlosburg, ... Neuropharmacology 76, 370-382, 2014 | 583 | 2014 |
| Individual differences in prefrontal cortex function and the transition from drug use to drug dependence O George, GF Koob Neuroscience & Biobehavioral Reviews 35 (2), 232-247, 2010 | 393 | 2010 |
| CRF–CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats O George, S Ghozland, MR Azar, P Cottone, EP Zorrilla, LH Parsons, ... Proceedings of the National Academy of Sciences 104 (43), 17198-17203, 2007 | 308 | 2007 |
| Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking O George, C Sanders, J Freiling, E Grigoryan, S Vu, CD Allen, E Crawford, ... Proceedings of the National Academy of Sciences 109 (44), 18156-18161, 2012 | 279 | 2012 |
| Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems O George, M Le Moal, GF Koob Physiology & behavior 106 (1), 58-64, 2012 | 242 | 2012 |
| Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals LF Vendruscolo, D Estey, V Goodell, LG Macshane, ML Logrip, ... The Journal of clinical investigation 125 (8), 3193-3197, 2015 | 231 | 2015 |
| Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairments O George, CD Mandyam, S Wee, GF Koob Neuropsychopharmacology 33 (10), 2474-2482, 2008 | 203 | 2008 |
| Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal R Zhao-Shea, SR DeGroot, L Liu, M Vallaster, X Pang, Q Su, G Gao, ... Nature communications 6 (1), 6770, 2015 | 156 | 2015 |
| VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation TE Grieder, MA Herman, C Contet, LA Tan, H Vargas-Perez, A Cohen, ... Nature neuroscience 17 (12), 1751-1758, 2014 | 149 | 2014 |
| Individual differences in the neuropsychopathology of addiction O George, GF Koob Dialogues in clinical neuroscience 19 (3), 217-229, 2017 | 142 | 2017 |
| Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake JE Schlosburg, TW Whitfield, PE Park, EF Crawford, O George, ... Journal of Neuroscience 33 (49), 19384-19392, 2013 | 138 | 2013 |
| Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats G de Guglielmo, M Kallupi, MB Pomrenze, E Crawford, S Simpson, ... Nature Communications 10 (1), 1238, 2019 | 136 | 2019 |
| A transgenic rat for investigating the anatomy and function of corticotrophin releasing factor circuits MB Pomrenze, EZ Millan, FW Hopf, R Keiflin, R Maiya, A Blasio, J Dadgar, ... Frontiers in neuroscience 9, 487, 2015 | 133 | 2015 |
| A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions L Orio, S Edwards, O George, LH Parsons, GF Koob Journal of Neuroscience 29 (15), 4846-4857, 2009 | 126 | 2009 |
| Levels of neural progenitors in the hippocampus predict memory impairment and relapse to drug seeking as a function of excessive methamphetamine self-administration P Recinto, ARH Samant, G Chavez, A Kim, CJ Yuan, M Soleiman, Y Grant, ... Neuropsychopharmacology 37 (5), 1275-1287, 2012 | 111 | 2012 |
| Motherhood‐induced memory improvement persists across lifespan in rats but is abolished by a gestational stress V Lemaire, JM Billard, P Dutar, O George, PV Piazza, J Epelbaum, ... European Journal of Neuroscience 23 (12), 3368-3374, 2006 | 106 | 2006 |
| Recruitment of a neuronal ensemble in the central nucleus of the amygdala is required for alcohol dependence G de Guglielmo, E Crawford, S Kim, LF Vendruscolo, BT Hope, ... Journal of Neuroscience 36 (36), 9446-9453, 2016 | 103 | 2016 |
| Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence A Cohen, GF Koob, O George Neuropsychopharmacology 37 (9), 2153-2160, 2012 | 93 | 2012 |
| Voluntary urination control by brainstem neurons that relax the urethral sphincter JA Keller, J Chen, S Simpson, EHJ Wang, V Lilascharoen, O George, ... Nature neuroscience 21 (9), 1229-1238, 2018 | 90 | 2018 |
| Brain-wide functional architecture remodeling by alcohol dependence and abstinence A Kimbrough, DJ Lurie, A Collazo, M Kreifeldt, H Sidhu, GC Macedo, ... Proceedings of the National Academy of Sciences 117 (4), 2149-2159, 2020 | 89 | 2020 |
George KoobDirector, National Institute on Alcohol Abuse and AlcoholismAdresse e-mail validée de nih.gov
