Grant W Brown

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Charles BooneProfessor, Donnelly Centre, University of TorontoAdresse e-mail validée de utoronto.ca
Michael ChangEuropean Research Institute for the Biology of AgeingAdresse e-mail validée de umcg.nl
Michael Costanzouniversity of torontoAdresse e-mail validée de utoronto.ca
Brenda AndrewsDirector, The Donnelly Centre, University of TorontoAdresse e-mail validée de utoronto.ca
Corey NislowProfessor, CRC Tier 1 in Translational Genomics, University of British ColumbiaAdresse e-mail validée de ubc.ca
Anastasia BaryshnikovaPrincipal Investigator, Calico Life SciencesAdresse e-mail validée de calicolabs.com
Chad MyersUniversity of MinnesotaAdresse e-mail validée de umn.edu
Jessica Vaisica, Ph.D.Graduate Student, University of TorontoAdresse e-mail validée de mail.utoronto.ca
Zhaolei Zhang, ProfessorUniversity of Toronto, Donnelly Centre, Dept of Molecular Genetics, Dept of Computer ScienceAdresse e-mail validée de utoronto.ca
anne-claude gingrasLunenfeld-Tanenbaum Research Institute; University of TorontoAdresse e-mail validée de lunenfeld.ca
Timothy R. HughesUniversity of TorontoAdresse e-mail validée de utoronto.ca
Csanad Z. BachratiUniversity of LincolnAdresse e-mail validée de lincoln.ac.uk
TaeHyung Simon KimUniversity of TorontoAdresse e-mail validée de mail.utoronto.ca
Guri Nina GiaeverAssociate Professor, Faculty of Pharmaceutical Sciences, University of British ColumbiaAdresse e-mail validée de UBC.ca
Daniel DurocherThe Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of MolecularAdresse e-mail validée de lunenfeld.ca
Marcus SmolkaCornell UniversityAdresse e-mail validée de cornell.edu
Ridhdhi DesaiHarvard Medical School, Beth Israel Deaconess Medical CenterAdresse e-mail validée de bidmc.harvard.edu
Jason MoffatSenior Scientist & Program Head, Genetics & Genome Biology, Sickkids Hospital; Professor, UofTAdresse e-mail validée de utoronto.ca
Michael RiffleUniversity of WashingtonAdresse e-mail validée de uw.edu
Jasper RineUC BerkeleyAdresse e-mail validée de berkeley.edu

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Grant W Brown

University of Toronto

Adresse e-mail validée de utoronto.ca - Page d'accueil

DNA Replication Genomic Instability


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Global mapping of the yeast genetic interaction network AHY Tong, G Lesage, GD Bader, H Ding, H Xu, X Xin, J Young, GF Berriz, ... science 303 (5659), 808-813, 2004	2567	2004
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map SR Collins, KM Miller, NL Maas, A Roguev, J Fillingham, CS Chu, ... Nature 446 (7137), 806-810, 2007	1037	2007
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways AB Parsons, RL Brost, H Ding, Z Li, C Zhang, B Sheikh, GW Brown, ... Nature biotechnology 22 (1), 62-69, 2004	771	2004
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress JM Tkach, A Yimit, AY Lee, M Riffle, M Costanzo, D Jaschob, JA Hendry, ... Nature cell biology 14 (9), 966-976, 2012	588	2012
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ... Nature communications 8 (1), 14432, 2017	552	2017
Regulation of chromosome replication TJ Kelly, GW Brown Annual review of biochemistry 69 (1), 829-880, 2000	552	2000
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase S Nagai, K Dubrana, M Tsai-Pflugfelder, MB Davidson, TM Roberts, ... Science 322 (5901), 597-602, 2008	517	2008
Unification of protein abundance datasets yields a quantitative Saccharomyces cerevisiae proteome B Ho, A Baryshnikova, GW Brown Cell systems 6 (2), 192-205. e3, 2018	493	2018
A genetic map of the response to DNA damage in human cells M Olivieri, T Cho, A Álvarez-Quilón, K Li, MJ Schellenberg, ... Cell 182 (2), 481-496. e21, 2020	460	2020
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale A Baryshnikova, M Costanzo, Y Kim, H Ding, J Koh, K Toufighi, JY Youn, ... Nature methods 7 (12), 1017-1024, 2010	439	2010
A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage M Chang, M Bellaoui, C Boone, GW Brown Proceedings of the National Academy of Sciences 99 (26), 16934-16939, 2002	363	2002
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates L Wu, CZ Bachrati, J Ou, C Xu, J Yin, M Chang, W Wang, L Li, GW Brown, ... Proceedings of the National Academy of Sciences 103 (11), 4068-4073, 2006	321	2006
Systematic analysis of complex genetic interactions E Kuzmin, B VanderSluis, W Wang, G Tan, R Deshpande, Y Chen, M Usaj, ... Science 360 (6386), eaao1729, 2018	295	2018
Mapping the cellular response to small molecules using chemogenomic fitness signatures AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ... Science 344 (6180), 208-211, 2014	279	2014
The synthetic genetic interaction spectrum of essential genes AP Davierwala, J Haynes, Z Li, RL Brost, MD Robinson, L Yu, ... Nature genetics 37 (10), 1147-1152, 2005	276	2005
Identification of protein complexes required for efficient sister chromatid cohesion ML Mayer, I Pot, M Chang, H Xu, V Aneliunas, T Kwok, R Newitt, ... Molecular biology of the cell 15 (4), 1736-1745, 2004	275	2004
Regulation of the replication initiator protein p65 cdc18 by CDK phosphorylation PV Jallepalli, GW Brown, M Muzi-Falconi, D Tien, TJ Kelly Genes & development 11 (21), 2767-2779, 1997	236	1997
RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability D Xu, R Guo, A Sobeck, CZ Bachrati, J Yang, T Enomoto, GW Brown, ... Genes & development 22 (20), 2843-2855, 2008	224	2008
Exploiting DNA replication stress for cancer treatment T Ubhi, GW Brown Cancer research 79 (8), 1730-1739, 2019	217	2019
The endonuclease Cue2 cleaves mRNAs at stalled ribosomes during No Go Decay KN D'Orazio, CCC Wu, N Sinha, R Loll-Krippleber, GW Brown, R Green Elife 8, e49117, 2019	213	2019

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