Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review L Schiffer, L Barnard, ES Baranowski, LC Gilligan, AE Taylor, W Arlt, ... The Journal of steroid biochemistry and molecular biology 194, 105439, 2019 | 368 | 2019 |
Intracrine androgen biosynthesis, metabolism and action revisited L Schiffer, W Arlt, KH Storbeck Molecular and cellular endocrinology 465, 4-26, 2018 | 221 | 2018 |
Mechanisms in endocrinology: the sexually dimorphic role of androgens in human metabolic disease L Schiffer, P Kempegowda, W Arlt, MW O’Reilly European journal of endocrinology 177 (3), R125-R143, 2017 | 167 | 2017 |
Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism KH Storbeck, L Schiffer, ES Baranowski, V Chortis, A Prete, L Barnard, ... Endocrine reviews 40 (6), 1605-1625, 2019 | 129 | 2019 |
The CYP11B subfamily L Schiffer, S Anderko, F Hannemann, A Eiden-Plach, R Bernhardt The Journal of steroid biochemistry and molecular biology 151, 38-51, 2015 | 77 | 2015 |
A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale L Schiffer, S Anderko, A Hobler, F Hannemann, N Kagawa, R Bernhardt Microbial Cell Factories 14, 1-12, 2015 | 46 | 2015 |
Measurement of salivary adrenal-specific androgens as biomarkers of therapy control in 21-hydroxylase deficiency I Bacila, J Adaway, J Hawley, S Mahdi, R Krone, L Patel, S Alvi, T Randell, ... The Journal of Clinical Endocrinology & Metabolism 104 (12), 6417-6429, 2019 | 42 | 2019 |
Understanding the role of androgen action in female adipose tissue L Schiffer, W Arlt, MW O’Reilly Hyperandrogenism in women 53, 33-49, 2019 | 41 | 2019 |
Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride L Schiffer, F Shaheen, LC Gilligan, KH Storbeck, JM Hawley, BG Keevil, ... Journal of Chromatography B 1209, 123413, 2022 | 36 | 2022 |
A CYP21A2 based whole-cell system in Escherichia coli for the biotechnological production of premedrol S Brixius-Anderko, L Schiffer, F Hannemann, B Janocha, R Bernhardt Microbial Cell Factories 14, 1-14, 2015 | 35 | 2015 |
Metabolism of oral turinabol by human steroid hormone–synthesizing cytochrome P450 enzymes L Schiffer, S Brixius-Anderko, F Hannemann, J Zapp, J Neunzig, M Thevis, ... Drug Metabolism and Disposition 44 (2), 227-237, 2016 | 33 | 2016 |
Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle … L Schiffer, P Kempegowda, AJ Sitch, JE Adaway, F Shaheen, A Ebbehoj, ... European Journal of Endocrinology 188 (1), 86-100, 2023 | 27 | 2023 |
11-Oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool L Barnard, L Schiffer, R Louw Du-Toit, JA Tamblyn, S Chen, D Africander, ... Endocrinology 162 (3), bqaa231, 2021 | 26 | 2021 |
The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1 L Barnard, N Nikolaou, C Louw, L Schiffer, H Gibson, LC Gilligan, ... The Journal of steroid biochemistry and molecular biology 202, 105724, 2020 | 25 | 2020 |
The steroid metabolite 16 (β)-OH-androstenedione generated by CYP21A2 serves as a substrate for CYP19A1 J Neunzig, M Milhim, L Schiffer, Y Khatri, J Zapp, A Sanchez-Guijo, ... The Journal of Steroid Biochemistry and Molecular Biology 167, 182-191, 2017 | 25 | 2017 |
Intracrine testosterone activation in human pancreatic β-cells stimulates insulin secretion W Xu, L Schiffer, MMF Qadir, Y Zhang, J Hawley, P Mota De Sa, ... Diabetes 69 (11), 2392-2399, 2020 | 24 | 2020 |
Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells W Xu, MMF Qadir, D Nasteska, PM de Sa, CM Gorvin, ... Cell reports 42 (5), 2023 | 18 | 2023 |
A liquid chromatography-tandem mass spectrometry assay for the profiling of classical and 11-oxygenated androgens in saliva L Schiffer, JE Adaway, W Arlt, BG Keevil Annals of Clinical Biochemistry 56 (5), 564-573, 2019 | 18 | 2019 |
Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens L Schiffer, A Bossey, P Kempegowda, AE Taylor, I Akerman, ... European Journal of Endocrinology 184 (3), 353-363, 2021 | 17 | 2021 |
Biotransformation of the mineralocorticoid receptor antagonists spironolactone and canrenone by human CYP11B1 and CYP11B2: characterization of the products and their influence … L Schiffer, AR Müller, A Hobler, S Brixius-Anderko, J Zapp, F Hannemann, ... The Journal of Steroid Biochemistry and Molecular Biology 163, 68-76, 2016 | 13 | 2016 |