| Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... Neuron 84 (6), 1213-1225, 2014 | 610 | 2014 |
| Inhibiting drug efflux transporters improves efficacy of ALS therapeutics MR Jablonski, SS Markandaiah, D Jacob, NJ Meng, K Li, V Gennaro, ... Annals of clinical and translational neurology 1 (12), 996-1005, 2014 | 108 | 2014 |
| Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P‐Glycoprotein) in endothelial cells of the blood–brain barrier in mutant superoxide dismutase 1 … H Qosa, J Lichter, M Sarlo, SS Markandaiah, K McAvoy, JP Richard, ... Glia 64 (8), 1298-1313, 2016 | 75 | 2016 |
| Excess glutamate secreted from astrocytes drives upregulation of P-glycoprotein in endothelial cells in amyotrophic lateral sclerosis LA Mohamed, SS Markandaiah, S Bonanno, P Pasinelli, D Trotti Experimental neurology 316, 27-38, 2019 | 59 | 2019 |
| Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS LT Rosenblum, S Shamamandri-Markandaiah, B Ghosh, E Foran, ... Experimental neurology 292, 145-153, 2017 | 34 | 2017 |
| Blood–brain barrier driven pharmacoresistance in amyotrophic lateral sclerosis and challenges for effective drug therapies LA Mohamed, S Markandaiah, S Bonanno, P Pasinelli, D Trotti The AAPS journal 19, 1600-1614, 2017 | 33 | 2017 |
| A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ... Scientific reports 12 (1), 5644, 2022 | 23 | 2022 |
| C9orf72 poly (PR) mediated neurodegeneration is associated with nucleolar stress ME Cicardi, JH Hallgren, D Mawrie, K Krishnamurthy, SS Markandaiah, ... Iscience 26 (9), 2023 | 7 | 2023 |
| EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS MW Urban, BA Charsar, NM Heinsinger, SS Markandaiah, L Sprimont, ... Elife 12, RP89298, 2024 | 4 | 2024 |
| Kapβ2 is a modifier of the C9orf72-linked glycine-arginine dipeptide neurotoxicity ME Cicardi, V Kankate, S Sriramoji, K Krishnamurthy, SS Markandaiah, ... bioRxiv, 2022.09. 30.510384, 2022 | 3* | 2022 |
| Glucose hypometabolism prompts RAN translation and exacerbates C9orf72-related ALS/FTD phenotypes AT Nelson, ME Cicardi, SS Markandaiah, JYS Han, NJ Philp, E Welebob, ... EMBO reports 25 (5), 2479-2510, 2024 | 2 | 2024 |
| Aberrant expression of the axon guidance cue netrin-1 by SOD1-ALS astrocytes contributes to motor neuron degeneration. K Krishnamurthy, S Markandaiah, M Cicardi, B Ghosh, X Wen, K McAvoy, ... GLIA 69, E194-E194, 2021 | | 2021 |