Naive CD4+ T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude JJ Moon, HH Chu, M Pepper, SJ McSorley, SC Jameson, RM Kedl, ... Immunity 27 (2), 203-213, 2007 | 1154 | 2007 |
Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells JM Curtsinger, CS Schmidt, A Mondino, DC Lins, RM Kedl, MK Jenkins, ... The Journal of Immunology 162 (6), 3256-3262, 1999 | 970 | 1999 |
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8 KB Gorden, KS Gorski, SJ Gibson, RM Kedl, WC Kieper, X Qiu, MA Tomai, ... The Journal of Immunology 174 (3), 1259-1268, 2005 | 872 | 2005 |
T cell responses: naive to memory and everything in between ND Pennock, JT White, EW Cross, EE Cheney, BA Tamburini, RM Kedl Advances in physiology education 37 (4), 273-283, 2013 | 780 | 2013 |
T cells compete for access to antigen-bearing antigen-presenting cells RM Kedl, WA Rees, DA Hildeman, B Schaefer, T Mitchell, J Kappler, ... The Journal of experimental medicine 192 (8), 1105-1114, 2000 | 538 | 2000 |
Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod SJ Gibson, JM Lindh, TR Riter, RM Gleason, LM Rogers, AE Fuller, ... Cellular immunology 218 (1-2), 74-86, 2002 | 523 | 2002 |
Combined TLR and CD40 Triggering Induces Potent CD8+ T Cell Expansion with Variable Dependence on Type I IFN CL Ahonen, CL Doxsee, SM McGurran, TR Riter, WF Wade, RJ Barth, ... The Journal of experimental medicine 199 (6), 775-784, 2004 | 460 | 2004 |
The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion C Haluszczak, AD Akue, SE Hamilton, LDS Johnson, L Pujanauski, ... Journal of Experimental Medicine 206 (2), 435-448, 2009 | 458 | 2009 |
Observation of antigen-dependent CD8+ T-cell/dendritic cell interactions in vivo BC Schaefer, ML Schaefer, JW Kappler, P Marrack, RM Kedl Cellular immunology 214 (2), 110-122, 2001 | 440 | 2001 |
HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates U Wille-Reece, BJ Flynn, K Loré, RA Koup, RM Kedl, JJ Mattapallil, ... Proceedings of the National Academy of Sciences 102 (42), 15190-15194, 2005 | 425 | 2005 |
Mechanism of T cell tolerance induction by murine hepatic Kupffer cells Q You, L Cheng, RM Kedl, C Ju Hepatology 48 (3), 978-990, 2008 | 405 | 2008 |
CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen AN Desch, GJ Randolph, K Murphy, EL Gautier, RM Kedl, MH Lahoud, ... Journal of Experimental Medicine 208 (9), 1789-1797, 2011 | 366 | 2011 |
Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates U Wille-Reece, BJ Flynn, K Loré, RA Koup, AP Miles, A Saul, RM Kedl, ... The Journal of experimental medicine 203 (5), 1249-1258, 2006 | 361 | 2006 |
An inverse relationship between T cell receptor affinity and antigen dose during CD4+ T cell responses in vivo and in vitro W Rees, J Bender, TK Teague, RM Kedl, F Crawford, P Marrack, ... Proceedings of the National Academy of Sciences 96 (17), 9781-9786, 1999 | 323 | 1999 |
Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 or TLR9 agonists complexed to cationic liposomes K Zaks, M Jordan, A Guth, K Sellins, R Kedl, A Izzo, C Bosio, S Dow The Journal of Immunology 176 (12), 7335-7345, 2006 | 321 | 2006 |
T cells down-modulate peptide-MHC complexes on APCs in vivo RM Kedl, BC Schaefer, JW Kappler, P Marrack Nature immunology 3 (1), 27-32, 2002 | 295 | 2002 |
Immunological adjuvants promote activated T cell survival via induction of Bcl-3 TC Mitchell, D Hildeman, RM Kedl, TK Teague, BC Schaefer, J White, ... Nature immunology 2 (5), 397-402, 2001 | 295 | 2001 |
Epitope dominance, competition and T cell affinity maturation RM Kedl, JW Kappler, P Marrack Current opinion in immunology 15 (1), 120-127, 2003 | 285 | 2003 |
Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity JR Cubillos-Ruiz, X Engle, UK Scarlett, D Martinez, A Barber, R Elgueta, ... The Journal of clinical investigation 119 (8), 2231-2244, 2009 | 284 | 2009 |
Activation changes the spectrum but not the diversity of genes expressed by T cells TK Teague, D Hildeman, RM Kedl, T Mitchell, W Rees, BC Schaefer, ... Proceedings of the National Academy of Sciences 96 (22), 12691-12696, 1999 | 278 | 1999 |