| SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ... Cell 182 (2), 429-446. e14, 2020 | 1616 | 2020 |
| SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production G Chen, TR Korfhagen, Y Xu, J Kitzmiller, SE Wert, Y Maeda, A Gregorieff, ... The Journal of clinical investigation 119 (10), 2914-2924, 2009 | 447 | 2009 |
| SPDEF regulates goblet cell hyperplasia in the airway epithelium KS Park, TR Korfhagen, MD Bruno, JA Kitzmiller, H Wan, SE Wert, ... The Journal of clinical investigation 117 (4), 978-988, 2007 | 336 | 2007 |
| Localization of secretory mucins MUC5AC and MUC5B in normal/healthy human airways K Okuda, G Chen, DB Subramani, M Wolf, RC Gilmore, T Kato, ... American journal of respiratory and critical care medicine 199 (6), 715-727, 2019 | 279 | 2019 |
| Secretory cells dominate airway CFTR expression and function in human airway superficial epithelia K Okuda, H Dang, Y Kobayashi, G Carraro, S Nakano, G Chen, T Kato, ... American journal of respiratory and critical care medicine 203 (10), 1275-1289, 2021 | 173 | 2021 |
| Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation P Rajavelu, G Chen, Y Xu, JA Kitzmiller, TR Korfhagen, JA Whitsett The Journal of clinical investigation 125 (5), 2021-2031, 2015 | 168 | 2015 |
| Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity G Chen, TR Korfhagen, CL Karp, S Impey, Y Xu, SH Randell, J Kitzmiller, ... American journal of respiratory and critical care medicine 189 (3), 301-313, 2014 | 145 | 2014 |
| IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis G Chen, L Sun, T Kato, K Okuda, MB Martino, A Abzhanova, JM Lin, ... The Journal of clinical investigation 129 (10), 4433-4450, 2019 | 123 | 2019 |
| Spdef Null Mice Lack Conjunctival Goblet Cells and Provide a Model of Dry Eye CK Marko, BB Menon, G Chen, JA Whitsett, H Clevers, IK Gipson The American journal of pathology, 2013 | 115 | 2013 |
| Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation Z Pei, B Wang, G Chen, M Nagao, M Nakafuku, K Campbell Proceedings of the National Academy of Sciences 108 (4), 1675-1680, 2011 | 102 | 2011 |
| Foxa2 programs Th2 cell-mediated innate immunity in the developing lung G Chen, H Wan, F Luo, L Zhang, Y Xu, I Lewkowich, M Wills-Karp, ... The Journal of Immunology 184 (11), 6133-6141, 2010 | 90 | 2010 |
| FOXM1 promotes allergen-induced goblet cell metaplasia and pulmonary inflammation X Ren, TA Shah, V Ustiyan, Y Zhang, J Shinn, G Chen, JA Whitsett, ... Molecular and cellular biology, 2013 | 84 | 2013 |
| Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation Y Maeda, G Chen, Y Xu, HM Haitchi, L Du, AR Keiser, PH Howarth, ... American journal of respiratory and critical care medicine 184 (4), 421-429, 2011 | 78 | 2011 |
| XBP1S regulates MUC5B in a promoter variant–dependent pathway in idiopathic pulmonary fibrosis airway epithelia G Chen, CMP Ribeiro, L Sun, K Okuda, T Kato, RC Gilmore, MB Martino, ... American journal of respiratory and critical care medicine 200 (2), 220-234, 2019 | 71 | 2019 |
| Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium IC Wang, J Snyder, Y Zhang, J Lander, Y Nakafuku, J Lin, G Chen, ... Molecular and cellular biology 32 (19), 3838-3850, 2012 | 68 | 2012 |
| SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity TK Noah, YH Lo, A Price, G Chen, E King, MK Washington, BJ Aronow, ... Gastroenterology 144 (5), 1012-1023. e6, 2013 | 67 | 2013 |
| SAM-pointed domain ETS factor mediates epithelial cell–intrinsic innate immune signaling during airway mucous metaplasia TR Korfhagen, J Kitzmiller, G Chen, A Sridharan, HM Haitchi, RS Hegde, ... Proceedings of the National Academy of Sciences 109 (41), 16630-16635, 2012 | 58 | 2012 |
| Prevalence and mechanisms of mucus accumulation in COVID-19 lung disease T Kato, T Asakura, CE Edwards, H Dang, Y Mikami, K Okuda, G Chen, ... American journal of respiratory and critical care medicine 206 (11), 1336-1352, 2022 | 53 | 2022 |
| CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis Y Maeda, T Suzuki, X Pan, G Chen, S Pan, T Bartman, JA Whitsett Journal of Biological Chemistry 283 (23), 16084-16092, 2008 | 36 | 2008 |
| Role of Spdef in the regulation of Muc5b expression in the airways of naive and mucoobstructed mice G Chen, AS Volmer, KJ Wilkinson, Y Deng, LC Jones, D Yu, ... American journal of respiratory cell and molecular biology 59 (3), 383-396, 2018 | 31 | 2018 |
Scott RandellCell Biology and Physiology, UNC @ Chapel HillAdresse e-mail validée de med.unc.edu