James B Stewart

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Christoph FreyerKarolinska InstitutetAdresse e-mail validée de clinicalgenomics.se
Patrick F ChinneryUniversity of CambridgeAdresse e-mail validée de medschl.cam.ac.uk
Anna WredenbergAdresse e-mail validée de clinicalgenomics.se
Arnaud MOURIERIBGC (UMR5095-CNRS)Adresse e-mail validée de ibgc.cnrs.fr
Carlos T. MoraesProfessor of NeurologyAdresse e-mail validée de med.miami.edu
Maria FalkenbergProfessorAdresse e-mail validée de medkem.gu.se
Dusanka MilenkovicMPI AGEAdresse e-mail validée de age.mpg.de
Cláudia V. PereiraVanderbilt UniversityAdresse e-mail validée de vanderbilt.edu
Joanna L ElsonLecturer Mitochondrial GeneticsAdresse e-mail validée de ncl.ac.uk
Benedetta RuzzenenteINSERM, Institut ImagineAdresse e-mail validée de inserm.fr
Aleksandra TrifunovicUniversity of CologneAdresse e-mail validée de uk-koeln.de
Michal MinczukProfessor at Dept. Clinical Neurosciences & Group Leader at MRC MBU - University of CambridgeAdresse e-mail validée de mrc-mbu.cam.ac.uk
Milena Pintouniversity of miamiAdresse e-mail validée de med.miami.edu
Nadee NissankaPostdoctoral Associate, University of MiamiAdresse e-mail validée de med.miami.edu
Ilian AtanassovMax Planck Institute for Biology of AgingAdresse e-mail validée de age.mpg.de
Laura GreavesResearch Fellow, Newcastle UniversityAdresse e-mail validée de ncl.ac.uk
Bianca HabermannIBDM UMR7288 Aix-Marseille UniversityAdresse e-mail validée de univ-amu.fr
Brendan BattersbyInstitute of Biotechnology, University of HelsinkiAdresse e-mail validée de helsinki.fi
Francesco FratiProfessor of Zoology and Evolutionary Biology, Università di Siena, ItalyAdresse e-mail validée de unisi.it
Thomas R. BuckleyLandcare ResearchAdresse e-mail validée de landcareresearch.co.nz

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James B Stewart

Biosciences Institute, Faculty of Medical Sciences, Newcastle University

Adresse e-mail validée de newcastle.ac.uk - Page d'accueil

Mitochondria mutations mtDNA


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease JB Stewart, PF Chinnery Nature Reviews Genetics 16 (9), 530-542, 2015	998	2015
Incorporating molecular evolution into phylogenetic analysis, and a new compilation of conserved polymerase chain reaction primers for animal mitochondrial DNA C Simon, TR Buckley, F Frati, JB Stewart, AT Beckenbach Annu. Rev. Ecol. Evol. Syst. 37, 545-579, 2006	712	2006
Strong purifying selection in transmission of mammalian mitochondrial DNA JB Stewart, C Freyer, JL Elson, A Wredenberg, Z Cansu, A Trifunovic, ... PLoS biology 6 (1), e10, 2008	557	2008
LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs B Ruzzenente, MD Metodiev, A Wredenberg, A Bratic, CB Park, Y Cámara, ... The EMBO Journal, 2011	367	2011
Germline mitochondrial DNA mutations aggravate ageing and can impair brain development JM Ross, JB Stewart, E Hagström, S Brené, A Mourier, C Freyer, ... Nature 501, 412–415, 2013	301	2013
Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo PA Gammage, C Viscomi, ML Simard, ASH Costa, E Gaude, CA Powell, ... Nature Medicine 24 (11), 1691-1695, 2018	295	2018
MitoTALEN reduces mutant mtDNA load and restores tRNA Ala levels in a mouse model of heteroplasmic mtDNA mutation SR Bacman, JHK Kauppila, CV Pereira, N Nissanka, M Miranda, M Pinto, ... Nature Medicine 24 (11), 1696-1700, 2018	277	2018
Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins A Ameur, JB Stewart, C Freyer, E Hagström, M Ingman, NG Larsson, ... PLoS Genetics 7 (3), e1002028, 2011	272	2011
Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease JB Stewart, C Freyer, JL Elson, NG Larsson Nature Reviews Genetics 9 (9), 657-662, 2008	223	2008
Extreme heterogeneity of human mitochondrial DNA from organelles to populations JB Stewart, PF Chinnery Nature Reviews Genetics, https://doi.org/10.1038/s41576-020-00284, 2020	203	2020
MTERF1 Binds mtDNA to Prevent Transcriptional Interference at the Light-Strand Promoter but Is Dispensable for rRNA Gene Transcription Regulation M Terzioglu, B Ruzzenente, J Harmel, A Mourier, E Jemt, MD Lopez, ... Cell Metabolism 17 (4), 618-626, 2013	167	2013
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly O Rackham, JD Busch, S Matic, SJ Siira, I Kuznetsova, I Atanassov, ... Cell Reports 16 (7), 1874-1890, 2016	159	2016
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission C Freyer, LM Cree, A Mourier, JB Stewart, C Koolmeister, D Milenkovic, ... Nature Genetics 44 (11), 1282, 2012	145	2012
Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers JB Stewart, B Alaei-Mahabadi, R Sabarinathan, T Samuelsson, ... PLoS Genetics 11 (6), e1005333, 2015	135	2015
Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse R Filograna, C Koolmeister, M Upadhyay, A Pajak, P Clemente, R Wibom, ... Science Advances 5 (4), eaav9824, 2019	133	2019
No recombination of mtDNA after 50 generations in the mouse maternal germline. E Hagström, C Freyer, B Battersby, JB Stewart, NG Larsson Nucleic Acids Research 42 (2), 1111-1116, 2014	132*	2014
A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease JHK Kauppila, HL Baines, A Bratic, ML Simard, C Freyer, A Mourier, ... Cell Reports 16 (11), 2980–2990, 2016	131	2016
Keeping mtDNA in Shape between Generations JB Stewart, NG Larsson PLoS Genetics 10 (10), e1004670, 2014	127	2014
Increased Total mtDNA Copy Number Cures Male Infertility Despite Unaltered mtDNA Mutation Load M Jiang, TES Kauppila, E Motori, X Li, I Atanassov, K Folz-Donahue, ... Cell Metabolism 26 (2), 429-436. e4, 2017	126	2017
Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice X Zhou, N Solaroli, M Bjerke, JB Stewart, B Rozell, M Johansson, ... Human molecular genetics 17 (15), 2329, 2008	121	2008

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