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Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes”(KDIGO) Controversies Conference THJ Goodship, HT Cook, F Fakhouri, FC Fervenza, V Frémeaux-Bacchi, ... Kidney international 91 (3), 539-551, 2017 | 740 | 2017 |
An international consensus approach to the management of atypical hemolytic uremic syndrome in children C Loirat, F Fakhouri, G Ariceta, N Besbas, M Bitzan, A Bjerre, R Coppo, ... Pediatric nephrology 31, 15-39, 2016 | 715 | 2016 |
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test AC Lionel, G Costain, N Monfared, S Walker, MS Reuter, SM Hosseini, ... Genetics in Medicine 20 (4), 435-443, 2018 | 586 | 2018 |
Guideline for the investigation and initial therapy of diarrhea-negative hemolytic uremic syndrome G Ariceta, N Besbas, S Johnson, D Karpman, D Landau, C Licht, C Loirat, ... Pediatric nephrology 24, 687-696, 2009 | 497 | 2009 |
Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies C Licht, LA Greenbaum, P Muus, S Babu, CL Bedrosian, DJ Cohen, ... Kidney international 87 (5), 1061-1073, 2015 | 479 | 2015 |
Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency M Józsi, C Licht, S Strobel, SLH Zipfel, H Richter, S Heinen, PF Zipfel, ... Blood, The Journal of the American Society of Hematology 111 (3), 1512-1514, 2008 | 408 | 2008 |
Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy O Gross, C Licht, HJ Anders, B Hoppe, B Beck, B Tönshoff, B Höcker, ... Kidney international 81 (5), 494-501, 2012 | 405 | 2012 |
Deletion of Complement Factor H–Related Genes CFHR1 and CFHR3 Is Associated with Atypical Hemolytic Uremic Syndrome PF Zipfel, M Edey, S Heinen, M Józsi, H Richter, J Misselwitz, B Hoppe, ... PLoS genetics 3 (3), e41, 2007 | 404 | 2007 |
New approaches to the treatment of dense deposit disease RJH Smith, J Alexander, PN Barlow, M Botto, TL Cassavant, HT Cook, ... Journal of the American Society of Nephrology 18 (9), 2447-2456, 2007 | 358 | 2007 |
Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome LA Greenbaum, M Fila, G Ardissino, SI Al-Akash, J Evans, P Henning, ... Kidney international 89 (3), 701-711, 2016 | 316 | 2016 |
Abnormalities in the alternative pathway of complement in children with hematopoietic stem cell transplant-associated thrombotic microangiopathy S Jodele, C Licht, J Goebel, BP Dixon, K Zhang, TA Sivakumaran, ... Blood, The Journal of the American Society of Hematology 122 (12), 2003-2007, 2013 | 280 | 2013 |
Deletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II) C Licht, S Heinen, M Jozsi, I Löschmann, RE Saunders, SJ Perkins, ... Kidney international 70 (1), 42-50, 2006 | 261 | 2006 |
Eculizumab therapy in children with severe hematopoietic stem cell transplantation–associated thrombotic microangiopathy S Jodele, T Fukuda, A Vinks, K Mizuno, BL Laskin, J Goebel, BP Dixon, ... Biology of Blood and Marrow Transplantation 20 (4), 518-525, 2014 | 256 | 2014 |
aHUS caused by complement dysregulation: new therapies on the horizon AM Waters, C Licht Pediatric Nephrology 26, 41-57, 2011 | 213 | 2011 |
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration X Zhan, DE Larson, C Wang, DC Koboldt, YV Sergeev, RS Fulton, ... Nature genetics 45 (11), 1375-1379, 2013 | 192 | 2013 |
Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative CE Kashtan, J Ding, M Gregory, O Gross, L Heidet, B Knebelmann, ... Pediatric nephrology 28, 5-11, 2013 | 188 | 2013 |
Ethnic differences in incidence and outcomes of childhood nephrotic syndrome THM Banh, N Hussain-Shamsy, V Patel, J Vasilevska-Ristovska, ... Clinical Journal of the American Society of Nephrology 11 (10), 1760-1768, 2016 | 184 | 2016 |
Outrageous prices of orphan drugs: a call for collaboration L Luzzatto, HI Hyry, A Schieppati, E Costa, S Simoens, F Schaefer, ... The Lancet 392 (10149), 791-794, 2018 | 178 | 2018 |
Incidence of renal failure and nephroprotection by RAAS inhibition in heterozygous carriers of X-chromosomal and autosomal recessive Alport mutations J Temme, F Peters, K Lange, Y Pirson, L Heidet, R Torra, JP Grunfeld, ... Kidney international 81 (8), 779-783, 2012 | 168 | 2012 |