| Thermo and pH responsive polymers as gene delivery vectors: effect of polymer architecture on DNA complexation in vitro BR Twaites, C de las Heras Alarcón, D Cunliffe, M Lavigne, S Pennadam, ... Journal of controlled release 97 (3), 551-566, 2004 | 162 | 2004 |
| Thermoresponsive polymers as gene delivery vectors: cell viability, DNA transport and transfection studies BR Twaites, C de las Heras Alarcón, M Lavigne, A Saulnier, ... Journal of Controlled Release 108 (2-3), 472-483, 2005 | 124 | 2005 |
| Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate MD Lavigne, D Konstantopoulos, KZ Ntakou-Zamplara, A Liakos, ... Nature Communications 8 (1), 2076, 2017 | 78 | 2017 |
| Control of a multisubunit DNA motor by a thermoresponsive polymer switch SS Pennadam, MD Lavigne, CF Dutta, K Firman, D Mernagh, DC Górecki, ... Journal of the American Chemical Society 126 (41), 13208-13209, 2004 | 76 | 2004 |
| Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements A Antonaki, C Demetriades, A Polyzos, A Banos, G Vatsellas, MD Lavigne, ... Journal of Biological Chemistry 286 (44), 38768-38782, 2011 | 70 | 2011 |
| Emerging vectors and targeting methods for nonviral gene therapy MD Lavigne, DC Górecki Expert opinion on emerging drugs 11 (3), 541-557, 2006 | 65 | 2006 |
| Enhanced gene expression through temperature profile‐induced variations in molecular architecture of thermoresponsive polymer vectors MD Lavigne, SS Pennadam, J Ellis, LL Yates, C Alexander, DC Górecki The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2007 | 63 | 2007 |
| Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A IP Foskolou, D Stellas, I Rozani, MD Lavigne, PK Politis Oncogene 32 (8), 947-960, 2013 | 54 | 2013 |
| Composite macroH2A/NRF-1 nucleosomes suppress noise and generate robustness in gene expression MD Lavigne, G Vatsellas, A Polyzos, E Mantouvalou, G Sianidis, ... Cell reports 11 (7), 1090-1101, 2015 | 50 | 2015 |
| Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis M Armaka, D Konstantopoulos, C Tzaferis, MD Lavigne, M Sakkou, ... Genome Medicine 14 (1), 78, 2022 | 49 | 2022 |
| Nucleotide excision repair: from neurodegeneration to cancer A Liakos, MD Lavigne, M Fousteri Personalised Medicine: Lessons from Neurodegeneration to Cancer, 17-39, 2017 | 32 | 2017 |
| Nuclear‐targeted chimeric vector enhancing nonviral gene transfer into skeletal muscle of Fabry mice in vivo MD Lavigne, L Yates, P Coxhead, DC Górecki The FASEB Journal 22 (6), 2097-2107, 2008 | 30 | 2008 |
| Continuous transcription initiation guarantees robust repair of all transcribed genes and regulatory regions A Liakos, D Konstantopoulos, MD Lavigne, M Fousteri Nature Communications 11 (1), 916, 2020 | 29 | 2020 |
| The dual role of LSD1 and HDAC3 in STAT5-dependent transcription is determined by protein interactions, binding affinities, motifs and genomic positions A Nanou, C Toumpeki, MD Lavigne, V Lazou, J Demmers, T Paparountas, ... Nucleic Acids Research 45 (1), 142-154, 2017 | 27 | 2017 |
| Promoter Dependence of Plasmid–Pluronics Targeted α Galactosidase A Expression in Skeletal Muscle of Fabry Mice MD Lavigne, M Pohlschmidt, JF Novo, B Higgins, V Alakhov, ... Molecular Therapy 12 (5), 985-990, 2005 | 24 | 2005 |
| Synthesis and characterization of variable-architecture thermosensitive polymers for complexation with DNA SS Pennadam, JS Ellis, MD Lavigne, DC Górecki, MC Davies, ... Langmuir 23 (1), 41-49, 2007 | 22 | 2007 |
| Prox1 inhibits neurite outgrowth during central nervous system development V Kaltezioti, IP Foskolou, MD Lavigne, E Ninou, M Tsampoula, M Fousteri, ... Cellular and Molecular Life Sciences 78, 3443-3465, 2021 | 13 | 2021 |
| Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer’s disease D Charou, T Rogdakis, A Latorrata, M Valcarcel, V Papadogiannis, ... Stem Cell Research & Therapy 15 (1), 200, 2024 | 3 | 2024 |
| PSTVd infection in Nicotiana benthamiana plants has a minor yet detectable effect on CG methylation M Tselika, N Belmezos, P Kallemi, C Andronis, M Chiumenti, B Navarro, ... Frontiers in Plant Science 14, 1258023, 2023 | 3 | 2023 |
| Enhanced frequency of transcription pre-initiation complexes assembly after exposure to UV irradiation results in increased repair activity and reduced probabilities for … A Liakos, AC Synacheri, D Konstantopoulos, GC Stefos, MD Lavigne, ... Nucleic Acids Research 51 (16), 8575-8586, 2023 | 2 | 2023 |
Darek GoreckiUniversity of PortsmouthAdresse e-mail validée de port.ac.uk