Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis NJ Kang, SH Shin, HJ Lee, KW Lee Pharmacology & therapeutics 130 (3), 310-324, 2011 | 246 | 2011 |
Cocoa polyphenols suppress adipogenesis in vitro and obesity in vivo by targeting insulin receptor SY Min, H Yang, SG Seo, SH Shin, MY Chung, J Kim, SJ Lee, HJ Lee, ... International journal of obesity 37 (4), 584-592, 2013 | 128 | 2013 |
Precision medicine: the foundation of future cancer therapeutics SH Shin, AM Bode, Z Dong Npj precision oncology 1 (1), 12, 2017 | 123 | 2017 |
A comparative genomic approach for identifying synthetic lethal interactions in human cancer R Deshpande, MK Asiedu, M Klebig, S Sutor, E Kuzmin, J Nelson, ... Cancer research 73 (20), 6128-6136, 2013 | 73 | 2013 |
A small molecule inhibitor of the β-catenin-TCF4 interaction suppresses colorectal cancer growth in vitro and in vivo SH Shin, K Reddy, M Malakhova, F Liu, T Wang, M Song, H Chen, ... EBioMedicine 25, 22-31, 2017 | 60 | 2017 |
CDK12 and PAK2 as novel therapeutic targets for human gastric cancer H Liu, SH Shin, H Chen, T Liu, Z Li, Y Hu, F Liu, C Zhang, DJ Kim, K Liu, ... Theranostics 10 (14), 6201, 2020 | 57 | 2020 |
Sulforaphene suppresses growth of colon cancer‐derived tumors via induction of glutathione depletion and microtubule depolymerization S Byun, SH Shin, J Park, S Lim, E Lee, C Lee, D Sung, L Farrand, SR Lee, ... Molecular Nutrition & Food Research 60 (5), 1068-1078, 2016 | 57 | 2016 |
Addressing the challenges of applying precision oncology SH Shin, AM Bode, Z Dong NPJ precision oncology 1 (1), 28, 2017 | 55 | 2017 |
Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage SH Shin, SG Seo, S Min, H Yang, E Lee, JE Son, JY Kwon, S Yue, ... Journal of Agricultural and Food Chemistry 62 (19), 4306-4312, 2014 | 50 | 2014 |
A natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancer SH Shin, MH Lee, M Malakhova, I Kurinov, Q Wu, J Xu, Y Jiang, Z Dong, ... Oncotarget 7 (23), 35001, 2016 | 43 | 2016 |
A metabolite of daidzein, 6, 7, 4′‐trihydroxyisoflavone, suppresses adipogenesis in 3 T 3‐L 1 preadipocytes via ATP‐competitive inhibition of PI 3 K SG Seo, H Yang, SH Shin, S Min, YA Kim, JG Yu, DE Lee, MY Chung, ... Molecular nutrition & food research 57 (8), 1446-1455, 2013 | 42 | 2013 |
3, 3’‐Diindolylmethane suppresses high‐fat diet‐induced obesity through inhibiting adipogenesis of pre‐adipocytes by targeting USP2 activity H Yang, SG Seo, SH Shin, S Min, MJ Kang, R Yoo, JY Kwon, S Yue, ... Molecular nutrition & food research 61 (10), 1700119, 2017 | 40 | 2017 |
Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells SH Shin, JS Lee, JM Zhang, S Choi, ZV Boskovic, R Zhao, M Song, ... Science advances 6 (31), eaay9131, 2020 | 32 | 2020 |
Natural antioxidant and anti-inflammatory compounds in foodstuff or medicinal herbs inducing heme oxygenase-1 expression D Hahn, SH Shin, JS Bae Antioxidants 9 (12), 1191, 2020 | 31 | 2020 |
Inhibition of LTA4H by bestatin in human and mouse colorectal cancer S Zhao, K Yao, D Li, K Liu, G Jin, M Yan, Q Wu, H Chen, SH Shin, R Bai, ... EBioMedicine 44, 361-374, 2019 | 31 | 2019 |
Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c-Fos Degradation SH Shin, SR Lee, E Lee, KH Kim, S Byun Journal of natural products 80 (7), 2124-2130, 2017 | 25 | 2017 |
Targeting PRPK function blocks colon cancer metastasis T Zykova, F Zhu, L Wang, H Li, DY Lim, K Yao, E Roh, SP Yoon, HG Kim, ... Molecular cancer therapeutics 17 (5), 1101-1113, 2018 | 24 | 2018 |
γ‐Oryzanol Improves Exercise Endurance and Muscle Strength by Upregulating PPARδ and ERRγ Activity in Aged Mice J Ahn, HJ Son, HD Seo, TY Ha, J Ahn, H Lee, SH Shin, CH Jung, YJ Jang Molecular Nutrition & Food Research 65 (14), 2000652, 2021 | 22 | 2021 |
HOI-02 induces apoptosis and G2-M arrest in esophageal cancer mediated by ROS C Zhang, K Liu, K Yao, K Reddy, Y Zhang, Y Fu, G Yang, TA Zykova, ... Cell death & disease 6 (10), e1912-e1912, 2015 | 18 | 2015 |
Identification of a dual inhibitor of janus kinase 2 (JAK2) and p70 ribosomal S6 kinase1 (S6K1) pathways S Byun, S Lim, JY Mun, KH Kim, TR Ramadhar, L Farrand, SH Shin, ... Journal of Biological Chemistry 290 (39), 23553-23562, 2015 | 18 | 2015 |