| Copper (II) binding to α-synuclein, the Parkinson’s protein JC Lee, HB Gray, JR Winkler Journal of the American Chemical Society 130 (22), 6898-6899, 2008 | 260 | 2008 |
| Biophysics of α-synuclein membrane interactions CM Pfefferkorn, Z Jiang, JC Lee Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (2), 162-171, 2012 | 235 | 2012 |
| Cysteine cathepsins are essential in lysosomal degradation of α-synuclein RP McGlinchey, JC Lee Proceedings of the National Academy of Sciences 112 (30), 9322-9327, 2015 | 233 | 2015 |
| α-Synuclein interacts with Glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases TL Yap, JM Gruschus, A Velayati, W Westbroek, E Goldin, N Moaven, ... Journal of Biological Chemistry 286 (32), 28080-28088, 2011 | 228 | 2011 |
| α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease TK Rostovtseva, PA Gurnev, O Protchenko, DP Hoogerheide, TL Yap, ... Journal of Biological Chemistry 290 (30), 18467-18477, 2015 | 193 | 2015 |
| α-Synuclein structures from fluorescence energy-transfer kinetics: Implications for the role of the protein in Parkinson's disease JC Lee, R Langen, PA Hummel, HB Gray, JR Winkler Proceedings of the National Academy of Sciences of the United States of …, 2004 | 182 | 2004 |
| α-Synuclein: Stable compact and extended monomeric structures and pH dependence of dimer formation SL Bernstein, D Liu, T Wyttenbach, MT Bowers, JC Lee, HB Gray, ... Journal of the American Society for Mass Spectrometry 15 (10), 1435-1443, 2004 | 168 | 2004 |
| Cytochrome b562 folding triggered by electron transfer: approaching the speed limit for formation of a four-helix-bundle protein P Wittung-Stafshede, JC Lee, JR Winkler, HB Gray Proceedings of the National Academy of Sciences 96 (12), 6587-6590, 1999 | 159 | 1999 |
| Membrane Remodeling by α-Synuclein and Effects on Amyloid Formation Z Jiang, M de Messieres, JC Lee Journal of the American Chemical Society 135 (43), 15970-15973, 2013 | 141 | 2013 |
| Lipid-chaperone hypothesis: A common molecular mechanism of membrane disruption by intrinsically disordered proteins MF Sciacca, F Lolicato, C Tempra, F Scollo, BR Sahoo, MD Watson, ... ACS chemical neuroscience 11 (24), 4336-4350, 2020 | 134 | 2020 |
| Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity TL Yap, A Velayati, E Sidransky, JC Lee Molecular genetics and metabolism 108 (1), 56-64, 2013 | 128 | 2013 |
| Structural Insights into α-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations X Ni, RP McGlinchey, J Jiang, JC Lee Journal of molecular biology 431 (19), 3913-3919, 2019 | 127 | 2019 |
| Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17 CM Pfefferkorn, RP McGlinchey, JC Lee Proceedings of the National Academy of Sciences 107 (50), 21447-21452, 2010 | 118 | 2010 |
| Depth of α-synuclein in a bilayer determined by fluorescence, neutron reflectometry, and computation CM Pfefferkorn, F Heinrich, AJ Sodt, AS Maltsev, RW Pastor, JC Lee Biophysical journal 102 (3), 613-621, 2012 | 110 | 2012 |
| The protein-folding speed limit: intrachain diffusion times set by electron-transfer rates in denatured Ru (NH3) 5 (His-33)-Zn-cytochrome c IJ Chang, JC Lee, JR Winkler, HB Gray Proceedings of the National Academy of Sciences 100 (7), 3838-3840, 2003 | 103 | 2003 |
| Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy JCL JD Flynn, RP McGlinchey, RL Walker Journal of Biological Chemistry 293, 767-776, 2018 | 98 | 2018 |
| Tryptophan probes at the α-synuclein and membrane interface CM Pfefferkorn, JC Lee The Journal of Physical Chemistry B 114 (13), 4615-4622, 2010 | 93 | 2010 |
| Effects of phosphatidylcholine membrane fluidity on the conformation and aggregation of N-terminally acetylated α-synuclein EI O'Leary, Z Jiang, MP Strub, JC Lee Journal of Biological Chemistry 293 (28), 11195-11205, 2018 | 89 | 2018 |
| Tertiary contact formation in α-synuclein probed by electron transfer JC Lee, HB Gray, JR Winkler Journal of the American Chemical Society 127 (47), 16388-16389, 2005 | 81 | 2005 |
| α-Synuclein tertiary contact dynamics JC Lee, BT Lai, JJ Kozak, HB Gray, JR Winkler The Journal of Physical Chemistry B 111 (8), 2107-2112, 2007 | 79 | 2007 |
Harry B. GrayProfessor of Chemistry, California Institute of TechnologyAdresse e-mail validée de caltech.edu
