CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis IA Leclercq, GC Farrell, J Field, DR Bell, FJ Gonzalez, GR Robertson The Journal of clinical investigation 105 (8), 1067-1075, 2000 | 989 | 2000 |
Central role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice E Ip, GC Farrell, G Robertson, P Hall, R Kirsch, I Leclercq Hepatology 38 (1), 123-132, 2003 | 607 | 2003 |
Leptin is essential for the hepatic fibrogenic response to chronic liver injury IA Leclercq, GC Farrell, R Schriemer, GR Robertson Journal of hepatology 37 (2), 206-213, 2002 | 579 | 2002 |
II. Cytochrome P-450 enzymes and oxidative stress G Robertson, I Leclercq, GC Farrell American Journal of Physiology-Gastrointestinal and Liver Physiology 281 (5 …, 2001 | 532 | 2001 |
Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences IA Leclercq, ADS Morais, B Schroyen, N Van Hul, A Geerts Journal of hepatology 47 (1), 142-156, 2007 | 499 | 2007 |
Administration of the potent PPARα agonist, Wy‐14,643, reverses nutritional fibrosis and steatohepatitis in mice E Ip, G Farrell, P Hall, G Robertson, I Leclercq Hepatology 39 (5), 1286-1296, 2004 | 481 | 2004 |
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation I Gerin, LA Clerbaux, O Haumont, N Lanthier, AK Das, CF Burant, ... Journal of Biological Chemistry 285 (44), 33652-33661, 2010 | 435 | 2010 |
Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice R Español–Suñer, R Carpentier, N Van Hul, V Legry, Y Achouri, S Cordi, ... Gastroenterology 143 (6), 1564-1575. e7, 2012 | 402 | 2012 |
Experimental models of liver fibrosis S Crespo Yanguas, B Cogliati, J Willebrords, M Maes, I Colle, ... Archives of toxicology 90, 1025-1048, 2016 | 385 | 2016 |
NF-κB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis A dela Peña, I Leclercq, J Field, J George, B Jones, G Farrell Gastroenterology 129 (5), 1663-1674, 2005 | 357 | 2005 |
Mouse models of nonalcoholic steatohepatitis: toward optimization of their relevance to human nonalcoholic steatohepatitis G Farrell, JM Schattenberg, I Leclercq, MM Yeh, R Goldin, N Teoh, ... Hepatology 69 (5), 2241-2257, 2019 | 326 | 2019 |
Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis J George, N Pera, N Phung, I Leclercq, JY Hou, G Farrell Journal of hepatology 39 (5), 756-764, 2003 | 320 | 2003 |
Curcumin inhibits NF-κB activation and reduces the severity of experimental steatohepatitis in mice IA Leclercq, GC Farrell, C Sempoux, A dela Peña, Y Horsmans Journal of hepatology 41 (6), 926-934, 2004 | 309 | 2004 |
Kupffer cell activation is a causal factor for hepatic insulin resistance N Lanthier, O Molendi-Coste, Y Horsmans, N van Rooijen, PD Cani, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 298 (1 …, 2010 | 300 | 2010 |
Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells R Carpentier, RE Suñer, N Van Hul, JL Kopp, JB Beaudry, S Cordi, ... Gastroenterology 141 (4), 1432-1438. e4, 2011 | 299 | 2011 |
Why and how meet n‐3 PUFA dietary recommendations? O Molendi-Coste, V Legry, IA Leclercq Gastroenterology research and practice 2011 (1), 364040, 2011 | 279 | 2011 |
Kupffer cells mediate leptin-induced liver fibrosis J Wang, I Leclercq, JM Brymora, N Xu, M Ramezani–Moghadam, ... Gastroenterology 137 (2), 713-723. e1, 2009 | 268 | 2009 |
Effects of curcuminoids plus piperine on glycemic, hepatic and inflammatory biomarkers in patients with type 2 diabetes mellitus: a randomized double-blind placebo-controlled trial Y Panahi, N Khalili, E Sahebi, S Namazi, LE Simental-Mendía, M Majeed, ... Drug research 68 (07), 403-409, 2018 | 245 | 2018 |
Animal models for the study of hepatic fibrosis P Starkel, IA Leclercq Best practice & research Clinical gastroenterology 25 (2), 319-333, 2011 | 237 | 2011 |
COX‐2 induction in mice with experimental nutritional steatohepatitis: role as pro‐inflammatory mediator J Yu, E Ip, A dela Peña, JY Hou, J Sesha, N Pera, P Hall, R Kirsch, ... Hepatology 43 (4), 826-836, 2006 | 237 | 2006 |