| Green solid-phase peptide synthesis 2. 2-Methyltetrahydrofuran and ethyl acetate for solid-phase peptide synthesis under green conditions YE Jad, GA Acosta, T Govender, HG Kruger, A El-Faham, BG de la Torre, ... ACS Sustainable Chemistry & Engineering 4 (12), 6809-6814, 2016 | 7941 | 2016 |
| Current trends in computer aided drug design and a highlight of drugs discovered via computational techniques: A review VT Sabe, T Ntombela, LA Jhamba, GEM Maguire, T Govender, T Naicker, ... European Journal of Medicinal Chemistry 224, 113705, 2021 | 478 | 2021 |
| The role of nanotechnology in the treatment of viral infections L Singh, HG Kruger, GEM Maguire, T Govender, R Parboosing Therapeutic advances in infectious disease 4 (4), 105-131, 2017 | 406 | 2017 |
| Sulfonimidamides in medicinal and agricultural chemistry PK Chinthakindi, T Naicker, N Thota, T Govender, HG Kruger, ... Angewandte Chemie International Edition 56 (15), 4100-4109, 2017 | 189 | 2017 |
| Organocatalytic synthesis of chiral benzopyrans T Govender, L Hojabri, FM Moghaddam, PI Arvidsson Tetrahedron: Asymmetry 17 (12), 1763-1767, 2006 | 160 | 2006 |
| Integrated approach to structure-based enzymatic drug design: molecular modeling, spectroscopy, and experimental bioactivity B Honarparvar, T Govender, GEM Maguire, MES Soliman, HG Kruger Chemical reviews 114 (1), 493-537, 2014 | 145 | 2014 |
| Enantioselective organocatalyzed transformations of β-ketoesters T Govender, PI Arvidsson, GEM Maguire, HG Kruger, T Naicker Chemical Reviews 116 (16), 9375-9437, 2016 | 134 | 2016 |
| Enantioselective synthesis of chiral sulfones by Ir-catalyzed asymmetric hydrogenation: a facile approach to the preparation of chiral allylic and homoallylic compounds T Zhou, B Peters, MF Maldonado, T Govender, PG Andersson Journal of the American Chemical Society 134 (33), 13592-13595, 2012 | 120 | 2012 |
| Synthesis and biological evaluation of a teixobactin analogue YE Jad, GA Acosta, T Naicker, M Ramtahal, A El-Faham, T Govender, ... Organic letters 17 (24), 6182-6185, 2015 | 115 | 2015 |
| Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs J Joubert, WJ Geldenhuys, CJ Van der Schyf, DW Oliver, HG Kruger, ... ChemMedChem 7 (3), 375-384, 2012 | 108 | 2012 |
| Peptide synthesis beyond DMF: THF and ACN as excellent and friendlier alternatives YE Jad, GA Acosta, SN Khattab, BG de la Torre, T Govender, HG Kruger, ... Organic & biomolecular chemistry 13 (8), 2393-2398, 2015 | 102 | 2015 |
| A synthesis of “dual warhead” β-aryl ethenesulfonyl fluorides and one-pot reaction to β-sultams PK Chinthakindi, KB Govender, AS Kumar, HG Kruger, T Govender, ... Organic Letters 19 (3), 480-483, 2017 | 97 | 2017 |
| Short AntiMicrobial Peptides (SAMPs) as a class of extraordinary promising therapeutic agents S Ramesh, T Govender, HG Kruger, BG de la Torre, F Albericio Journal of Peptide Science 22 (7), 438-451, 2016 | 97 | 2016 |
| Preclinical evaluation of 68Ga-labeled 1, 4, 7-triazacyclononane-1, 4, 7-triacetic acid-ubiquicidin as a radioligand for PET infection imaging T Ebenhan, JR Zeevaart, JD Venter, T Govender, GH Kruger, NV Jarvis, ... Journal of Nuclear Medicine 55 (2), 308-314, 2014 | 94 | 2014 |
| 2-Methyltetrahydrofuran and cyclopentyl methyl ether for green solid-phase peptide synthesis YE Jad, GA Acosta, SN Khattab, BG de la Torre, T Govender, HG Kruger, ... Amino acids 48, 419-426, 2016 | 93 | 2016 |
| Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1, 2, 4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones NP Rai, VK Narayanaswamy, T Govender, BK Manuprasad, ... European journal of medicinal chemistry 45 (6), 2677-2682, 2010 | 88 | 2010 |
| Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development GL Moraes, GC Gomes, PRM De Sousa, CN Alves, T Govender, ... Tuberculosis 95 (2), 95-111, 2015 | 83 | 2015 |
| NOTA: a potent metallo-β-lactamase inhibitor AM Somboro, D Tiwari, LA Bester, R Parboosing, L Chonco, HG Kruger, ... Journal of Antimicrobial Chemotherapy 70 (5), 1594-1596, 2015 | 80 | 2015 |
| Anticancer activity of ruthenium (II) arene complexes bearing 1, 2, 3, 4-tetrahydroisoquinoline amino alcohol ligands MP Chelopo, SA Pawar, MK Sokhela, T Govender, HG Kruger, ... European Journal of Medicinal Chemistry 66, 407-414, 2013 | 74 | 2013 |
| Poly-N-methylated Amyloid β-Peptide (Aβ) C-Terminal Fragments Reduce Aβ Toxicity in Vitro and in Drosophila melanogaster P Pratim Bose, U Chatterjee, C Nerelius, T Govender, T Norstrom, ... Journal of medicinal chemistry 52 (24), 8002-8009, 2009 | 74 | 2009 |
Gert (HG) KrugerResearch Professor, Catalysis and Peptide Research Unit, UKZNAdresse e-mail validée de ukzn.ac.za