Christopher M Overall

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Georgina S. ButlerResearch Associate, Center for Blood Research, University of British Columbia, Canada.Adresse e-mail validée de ubc.ca
Ulrich auf dem KellerTechnical University of DenmarkAdresse e-mail validée de dtu.dk
Antoine DufourAssociate Professsor, University of CalgaryAdresse e-mail validée de ucalgary.ca
Ulrich Eckhard (ORCID:0000-0001-58...Group Leader, Department of Structural and Molecular Biology, IBMB-CSIC (ROR:05t8khn72)Adresse e-mail validée de ibmb.csic.es
Pitter F. HuesgenUniversity of Freiburg, CIBSS - Centre for Integrative Biological Signalling StudiesAdresse e-mail validée de biologie.uni-freiburg.de
Philipp F. LangeCanada Research Chair & Associate Professor of Pathology, University of British ColumbiaAdresse e-mail validée de ubc.ca
Theo KleinNetherlands Forensics Institute NFIAdresse e-mail validée de nfi.nl
Oliver SchillingUniversity of FreiburgAdresse e-mail validée de mol-med.uni-freiburg.de
Jayachandran N KizhakkedathuUniversity of British ColumbiaAdresse e-mail validée de pathology.ubc.ca
Jeff WranaSenior Investigator, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto; Professor, Dept. of Mol. Gen., U. ofAdresse e-mail validée de lunenfeld.ca
U. Margaretha WallonAssist. Professor, Lankenau Institute for Medical ResearchAdresse e-mail validée de MLHS.org
Nikolaus FortelnyUniversity of SalzburgAdresse e-mail validée de plus.ac.at
Steve WithersProfessor of Chemistry and Biochemistry, University Of British ColumbiaAdresse e-mail validée de chem.ubc.ca
Paul PavlidisProfessor of Psychiatry, University of British ColumbiaAdresse e-mail validée de msl.ubc.ca
Richard TingWeill Cornell Medicine, Department of RadiologyAdresse e-mail validée de med.cornell.edu
Yves DeClerckProfessor of Pediatrics and Biochemistry and Molecular BiologyAdresse e-mail validée de usc.edu
Tuula SaloUniversidade Estadual de Campinas (Faculdade de Odontologia de Piracicaba)Adresse e-mail validée de unicamp.br
Christoph Becker-PaulyProfessor of Biochemistry, University of KielAdresse e-mail validée de biochem.uni-kiel.de
Duanqing PeiWestlake UniversityAdresse e-mail validée de westlake.edu.cn
Peter FriedlRadboud University NijmegenAdresse e-mail validée de radboudumc.nl

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Christopher M Overall

University of British Columbia

Adresse e-mail validée de ubc.ca - Page d'accueil

proteomics degradomics protease MMP SARS-CoV-2 3CLpro


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Strategies for MMP inhibition in cancer: innovations for the post-trial era CM Overall, C López-Otín Nature Reviews Cancer 2 (9), 657-672, 2002	1742	2002
Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy CM Overall, O Kleifeld Nature Reviews Cancer 6 (3), 227-239, 2006	1456	2006
Human and mouse proteases: a comparative genomic approach XS Puente, LM Sánchez, CM Overall, C López-Otín Nature Reviews Genetics 4 (7), 544-558, 2003	1292	2003
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion K Wolf, YI Wu, Y Liu, J Geiger, E Tam, C Overall, MS Stack, P Friedl Nature cell biology 9 (8), 893-904, 2007	1253	2007
Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3 GA McQuibban, JH Gong, EM Tam, CAG McCulloch, I Clark-Lewis, ... Science 289 (5482), 1202-1206, 2000	983	2000
Protease degradomics: a new challenge for proteomics C López-Otín, CM Overall Nature reviews Molecular cell biology 3 (7), 509-519, 2002	968	2002
Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-β CM Overall, JL Wrana, J Sodek Journal of Biological Chemistry 264 (3), 1860-1869, 1989	852	1989
Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1 GA McQuibban, GS Butler, JH Gong, L Bendall, C Power, I Clark-Lewis, ... Journal of Biological Chemistry 276 (47), 43503-43508, 2001	803	2001
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011	791	2011
Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo GA McQuibban, JH Gong, JP Wong, JL Wallace, I Clark-Lewis, ... Blood, The Journal of the American Society of Hematology 100 (4), 1160-1167, 2002	778	2002
Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics D Rodríguez, CJ Morrison, CM Overall Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (1), 39-54, 2010	727	2010
Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites CM Overall Molecular biotechnology 22, 51-86, 2002	672	2002
Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with … CM Overall, JL Wrana, J Sodek Journal of Biological Chemistry 266 (21), 14064-14071, 1991	623	1991
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice M Balbín, A Fueyo, AM Tester, AM Pendás, AS Pitiot, A Astudillo, ... Nature genetics 35 (3), 252-257, 2003	600	2003
Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells R Khokha, P Waterhouse, S Yagel, PK Lala, CM Overall, G Norton, ... Science 243 (4893), 947-950, 1989	593	1989
Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products O Kleifeld, A Doucet, U auf dem Keller, A Prudova, O Schilling, ... Nature biotechnology 28 (3), 281-288, 2010	578	2010
Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: a comparison of sites in edentulous and partially edentulous patients P Apse, RP Ellen, CM Overall, GA Zarb Journal of periodontal research 24 (2), 96-105, 1989	535	1989
Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites O Schilling, CM Overall Nature biotechnology 26 (6), 685-694, 2008	452	2008
Towards third generation matrix metalloproteinase inhibitors for cancer therapy CM Overall, O Kleifeld British journal of cancer 94 (7), 941-946, 2006	429	2006
Proteolytic host cell enzymes in gingival crevice fluid. VJ Uitto, CM Overall, C McCulloch Periodontology 2000 31 (1), 2003	427	2003

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