Suivre
Johan Neyts
Johan Neyts
Professor of Virology @KU Leuven; Co-Founder AstriVax Therapeutics & VirusbankPlatform
Adresse e-mail validée de rega.kuleuven.be - Page d'accueil
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Année
Angiogenesis: regulators and clinical applications
S Liekens, E De Clercq, J Neyts
Biochemical pharmacology 61 (3), 253-270, 2001
11892001
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2
M McCallum, A De Marco, FA Lempp, MA Tortorici, D Pinto, AC Walls, ...
Cell 184 (9), 2332-2347. e16, 2021
9342021
Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture
AH De Wilde, D Jochmans, CC Posthuma, JC Zevenhoven-Dobbe, ...
Antimicrobial agents and chemotherapy 58 (8), 4875-4884, 2014
9182014
Animal models for COVID-19
C Muñoz-Fontela, WE Dowling, SGP Funnell, PS Gsell, AX Riveros-Balta, ...
Nature 586 (7830), 509-515, 2020
8822020
In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine
E Keyaerts, L Vijgen, P Maes, J Neyts, M Van Ranst
Biochemical and biophysical research communications 323 (1), 264-268, 2004
8622004
α-Ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication: structure-based design, synthesis, and activity assessment
L Zhang, D Lin, Y Kusov, Y Nian, Q Ma, J Wang, A Von Brunn, P Leyssen, ...
Journal of medicinal chemistry 63 (9), 4562-4578, 2020
6092020
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
M Guilliams, J Bonnardel, B Haest, B Vanderborght, C Wagner, ...
Cell 185 (2), 379-396. e38, 2022
5992022
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
MA Tortorici, M Beltramello, FA Lempp, D Pinto, HV Dang, LE Rosen, ...
Science 370 (6519), 950-957, 2020
5492020
An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus challenge
G Yang, DC Pevear, MH Davies, MS Collett, T Bailey, S Rippen, L Barone, ...
Journal of virology 79 (20), 13139-13149, 2005
5082005
Favipiravir as a potential countermeasure against neglected and emerging RNA viruses
L Delang, R Abdelnabi, J Neyts
Antiviral research 153, 85-94, 2018
4962018
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
E Mastrangelo, M Pezzullo, T De Burghgraeve, S Kaptein, B Pastorino, ...
Journal of Antimicrobial Chemotherapy 67 (8), 1884-1894, 2012
4822012
Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern
L Vangeel, W Chiu, S De Jonghe, P Maes, B Slechten, J Raymenants, ...
Antiviral research 198, 105252, 2022
4592022
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ...
Nature 597 (7874), 97-102, 2021
4582021
Structure and functionality in flavivirus NS-proteins: perspectives for drug design
M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ...
Antiviral research 87 (2), 125-148, 2010
4532010
The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine) n-specific plant lectin from Urtica dioica are potent and …
J Balzarini, J Neyts, D Schols, M Hosoya, E Van Damme, W Peumans, ...
Antiviral research 18 (2), 191-207, 1992
3601992
The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase
P Leyssen, J Balzarini, E De Clercq, J Neyts
Journal of virology 79 (3), 1943-1947, 2005
3512005
The non‐immunosuppressive cyclosporin DEBIO‐025 is a potent inhibitor of hepatitis C virus replication in vitro
J Paeshuyse, A Kaul, E De Clercq, B Rosenwirth, JM Dumont, P Scalfaro, ...
Hepatology 43 (4), 761-770, 2006
3502006
Broad betacoronavirus neutralization by a stem helix–specific human antibody
D Pinto, MM Sauer, N Czudnochowski, JS Low, MA Tortorici, MP Housley, ...
Science 373 (6559), 1109-1116, 2021
3442021
Perspectives for the Treatment of Infections withFlaviviridae
P Leyssen, E De Clercq, J Neyts
Clinical microbiology reviews 13 (1), 67-82, 2000
3352000
HPMPC (cidofovir), PMEA (adefovir) and related acyclic nucleoside phosphonate analogues: a review of their pharmacology and clinical potential in the treatment of viral infections
L Naesens, R Snoeck, G Andrei, J Balzarini, J Neyts, E De Clercq
Antiviral Chemistry and Chemotherapy 8 (1), 1-23, 1997
3251997
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