Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease A Gomez‐Arboledas, JC Davila, E Sanchez‐Mejias, V Navarro, ... Glia 66 (3), 637-653, 2018 | 197 | 2018 |
Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimer’s disease DI Javonillo, KM Tran, J Phan, E Hingco, EA Kramár, C da Cunha, ... Frontiers in Neuroscience 15, 785276, 2022 | 115 | 2022 |
The role of complement in synaptic pruning and neurodegeneration A Gomez-Arboledas, MM Acharya, AJ Tenner ImmunoTargets and Therapy, 373-386, 2021 | 93 | 2021 |
Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1 R March-Diaz, N Lara-Ureña, C Romero-Molina, A Heras-Garvin, ... Nature Aging 1 (4), 385-399, 2021 | 84 | 2021 |
Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum L Trujillo-Estrada, JC Dávila, E Sánchez-Mejias, R Sánchez-Varo, ... Journal of Alzheimer's Disease 42 (2), 521-541, 2014 | 72 | 2014 |
Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease MV Sanchez‐Mico, S Jimenez, A Gomez‐Arboledas, C Muñoz‐Castro, ... Glia 69 (4), 997-1011, 2021 | 66 | 2021 |
Distinct disease‐sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients E Sanchez‐Mejias, C Nuñez‐Diaz, R Sanchez‐Varo, ... Brain Pathology 30 (2), 345-363, 2020 | 65 | 2020 |
Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model JJ Fernandez-Valenzuela, R Sanchez-Varo, C Muñoz-Castro, ... Scientific reports 10 (1), 14776, 2020 | 57 | 2020 |
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease D Baglietto-Vargas, E Sánchez-Mejias, V Navarro, S Jimenez, ... Scientific Reports 7 (1), 10085, 2017 | 42 | 2017 |
C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer’s disease A Gomez-Arboledas, K Carvalho, G Balderrama-Gutierrez, SH Chu, ... Acta neuropathologica communications 10 (1), 116, 2022 | 34 | 2022 |
Astrocytes: from the physiology to the disease L Trujillo-Estrada, A Gomez-Arboledas, S Forner, AC Martini, A Gutierrez, ... Current Alzheimer Research 16 (8), 675-698, 2019 | 33 | 2019 |
Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression K Carvalho, ND Schartz, G Balderrama-Gutierrez, HY Liang, SH Chu, ... Journal of neuroinflammation 19 (1), 178, 2022 | 30 | 2022 |
A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques KM Tran, S Kawauchi, EA Kramár, N Rezaie, HY Liang, JS Sakr, ... Molecular neurodegeneration 18 (1), 12, 2023 | 27 | 2023 |
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling A Cadete Martini, A Gomez-Arboledas, S Forner, CJ Rodriguez-Ortiz, ... Proceedings of the National Academy of Sciences 116 (42), 21198-21206, 2019 | 24 | 2019 |
Plaque-associated oligomeric amyloid-beta drives early synaptotoxicity in APP/PS1 mice hippocampus: ultrastructural pathology analysis R Sanchez-Varo, E Sanchez-Mejias, JJ Fernandez-Valenzuela, ... Frontiers in Neuroscience 15, 752594, 2021 | 23 | 2021 |
Complement as a powerful “influencer” in the brain during development, adulthood and neurological disorders TJ Petrisko, A Gomez-Arboledas, AJ Tenner Advances in immunology 152, 157-222, 2021 | 19 | 2021 |
Enhancing microtubule stabilization rescues cognitive deficits and ame‑liorates pathological phenotype in an amyloidogenic Alzheimer’s disease model. Sci Rep 10: 14776 JJ Fernandez‑Valenzuela, R Sanchez‑Varo, C Muñoz‑Castro, ... s4 1598-020-71767-4, 2020 | 7 | 2020 |
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease N Soni, LA Hohsfield, KM Tran, S Kawauchi, A Walker, D Javonillo, ... Alzheimer's & Dementia 20 (4), 2794-2816, 2024 | 5 | 2024 |
C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer’s model ND Schartz, HY Liang, K Carvalho, SH Chu, A Mendoza-Arvilla, ... bioRxiv, 2023 | 4 | 2023 |
C5aR1 antagonism suppresses inflammatory glial responses and alters cellular signaling in an Alzheimer’s disease mouse model ND Schartz, HY Liang, K Carvalho, SH Chu, A Mendoza-Arvilla, ... Nature communications 15 (1), 7028, 2024 | 3 | 2024 |