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Angela Gomez-Arboledas
Angela Gomez-Arboledas
PhD, University of California Irvine
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Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease
A Gomez‐Arboledas, JC Davila, E Sanchez‐Mejias, V Navarro, ...
Glia 66 (3), 637-653, 2018
1972018
Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimer’s disease
DI Javonillo, KM Tran, J Phan, E Hingco, EA Kramár, C da Cunha, ...
Frontiers in Neuroscience 15, 785276, 2022
1152022
The role of complement in synaptic pruning and neurodegeneration
A Gomez-Arboledas, MM Acharya, AJ Tenner
ImmunoTargets and Therapy, 373-386, 2021
932021
Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
R March-Diaz, N Lara-Ureña, C Romero-Molina, A Heras-Garvin, ...
Nature Aging 1 (4), 385-399, 2021
842021
Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum
L Trujillo-Estrada, JC Dávila, E Sánchez-Mejias, R Sánchez-Varo, ...
Journal of Alzheimer's Disease 42 (2), 521-541, 2014
722014
Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease
MV Sanchez‐Mico, S Jimenez, A Gomez‐Arboledas, C Muñoz‐Castro, ...
Glia 69 (4), 997-1011, 2021
662021
Distinct disease‐sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients
E Sanchez‐Mejias, C Nuñez‐Diaz, R Sanchez‐Varo, ...
Brain Pathology 30 (2), 345-363, 2020
652020
Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease model
JJ Fernandez-Valenzuela, R Sanchez-Varo, C Muñoz-Castro, ...
Scientific reports 10 (1), 14776, 2020
572020
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease
D Baglietto-Vargas, E Sánchez-Mejias, V Navarro, S Jimenez, ...
Scientific Reports 7 (1), 10085, 2017
422017
C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer’s disease
A Gomez-Arboledas, K Carvalho, G Balderrama-Gutierrez, SH Chu, ...
Acta neuropathologica communications 10 (1), 116, 2022
342022
Astrocytes: from the physiology to the disease
L Trujillo-Estrada, A Gomez-Arboledas, S Forner, AC Martini, A Gutierrez, ...
Current Alzheimer Research 16 (8), 675-698, 2019
332019
Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression
K Carvalho, ND Schartz, G Balderrama-Gutierrez, HY Liang, SH Chu, ...
Journal of neuroinflammation 19 (1), 178, 2022
302022
A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaques
KM Tran, S Kawauchi, EA Kramár, N Rezaie, HY Liang, JS Sakr, ...
Molecular neurodegeneration 18 (1), 12, 2023
272023
Amyloid-beta impairs TOM1-mediated IL-1R1 signaling
A Cadete Martini, A Gomez-Arboledas, S Forner, CJ Rodriguez-Ortiz, ...
Proceedings of the National Academy of Sciences 116 (42), 21198-21206, 2019
242019
Plaque-associated oligomeric amyloid-beta drives early synaptotoxicity in APP/PS1 mice hippocampus: ultrastructural pathology analysis
R Sanchez-Varo, E Sanchez-Mejias, JJ Fernandez-Valenzuela, ...
Frontiers in Neuroscience 15, 752594, 2021
232021
Complement as a powerful “influencer” in the brain during development, adulthood and neurological disorders
TJ Petrisko, A Gomez-Arboledas, AJ Tenner
Advances in immunology 152, 157-222, 2021
192021
Enhancing microtubule stabilization rescues cognitive deficits and ame‑liorates pathological phenotype in an amyloidogenic Alzheimer’s disease model. Sci Rep 10: 14776
JJ Fernandez‑Valenzuela, R Sanchez‑Varo, C Muñoz‑Castro, ...
s4 1598-020-71767-4, 2020
72020
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease
N Soni, LA Hohsfield, KM Tran, S Kawauchi, A Walker, D Javonillo, ...
Alzheimer's & Dementia 20 (4), 2794-2816, 2024
52024
C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer’s model
ND Schartz, HY Liang, K Carvalho, SH Chu, A Mendoza-Arvilla, ...
bioRxiv, 2023
42023
C5aR1 antagonism suppresses inflammatory glial responses and alters cellular signaling in an Alzheimer’s disease mouse model
ND Schartz, HY Liang, K Carvalho, SH Chu, A Mendoza-Arvilla, ...
Nature communications 15 (1), 7028, 2024
32024
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