| MeCP2, a key contributor to neurological disease, activates and represses transcription M Chahrour, SY Jung, C Shaw, X Zhou, STC Wong, J Qin, HY Zoghbi Science 320 (5880), 1224-1229, 2008 | 2039 | 2008 |
| Multiple recurrent de novo CNVs, including duplications of the 7q11. 23 Williams syndrome region, are strongly associated with autism SJ Sanders, AG Ercan-Sencicek, V Hus, R Luo, MT Murtha, ... Neuron 70 (5), 863-885, 2011 | 1530 | 2011 |
| A protein–protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration J Lim, T Hao, C Shaw, AJ Patel, G Szabó, JF Rual, CJ Fisk, N Li, ... Cell 125 (4), 801-814, 2006 | 988 | 2006 |
| Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation SM Chambers, CA Shaw, C Gatza, CJ Fisk, LA Donehower, MA Goodell PLoS biology 5 (8), e201, 2007 | 930 | 2007 |
| Resolution of disease phenotypes resulting from multilocus genomic variation JE Posey, T Harel, P Liu, JA Rosenfeld, RA James, ZH Coban Akdemir, ... New England Journal of Medicine 376 (1), 21-31, 2017 | 706 | 2017 |
| Analysis of 13 cell types reveals evidence for the expression of numerous novel primate-and tissue-specific microRNAs E Londin, P Loher, AG Telonis, K Quann, P Clark, Y Jing, E Hatzimichael, ... Proceedings of the National Academy of Sciences 112 (10), E1106-E1115, 2015 | 540 | 2015 |
| A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models X Zhang, S Claerhout, A Prat, LE Dobrolecki, I Petrovic, Q Lai, MD Landis, ... Cancer research 73 (15), 4885-4897, 2013 | 539 | 2013 |
| The spliceosome is a therapeutic vulnerability in MYC-driven cancer TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ... Nature 525 (7569), 384-388, 2015 | 505 | 2015 |
| A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis JD Kessler, KT Kahle, T Sun, KL Meerbrey, MR Schlabach, EM Schmitt, ... Science 335 (6066), 348-353, 2012 | 463 | 2012 |
| Use of exome sequencing for infants in intensive care units: ascertainment of severe single-gene disorders and effect on medical management L Meng, M Pammi, A Saronwala, P Magoulas, AR Ghazi, F Vetrini, ... JAMA pediatrics 171 (12), e173438-e173438, 2017 | 444 | 2017 |
| Molecular signatures of proliferation and quiescence in hematopoietic stem cells TA Venezia, AA Merchant, CA Ramos, NL Whitehouse, AS Young, ... PLoS biology 2 (10), e301, 2004 | 437 | 2004 |
| Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression MS Bray, CA Shaw, MWS Moore, RAP Garcia, MM Zanquetta, DJ Durgan, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (2 …, 2008 | 419 | 2008 |
| Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity S Nagalla, C Shaw, X Kong, AA Kondkar, LC Edelstein, L Ma, J Chen, ... Blood, The Journal of the American Society of Hematology 117 (19), 5189-5197, 2011 | 417 | 2011 |
| Hematopoietic fingerprints: an expression database of stem cells and their progeny SM Chambers, NC Boles, KYK Lin, MP Tierney, TV Bowman, SB Bradfute, ... Cell stem cell 1 (5), 578-591, 2007 | 338 | 2007 |
| Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase T Sun, N Aceto, KL Meerbrey, JD Kessler, C Zhou, I Migliaccio, ... Cell 144 (5), 703-718, 2011 | 323 | 2011 |
| Development and validation of a CGH microarray for clinical cytogenetic diagnosis SW Cheung, CA Shaw, W Yu, J Li, Z Ou, A Patel, SA Yatsenko, ... Genetics in Medicine 7 (6), 422-432, 2005 | 316 | 2005 |
| Somatic mosaicism: implications for disease and transmission genetics IM Campbell, CA Shaw, P Stankiewicz, JR Lupski Trends in Genetics 31 (7), 382-392, 2015 | 308 | 2015 |
| MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome L Chen, K Chen, LA Lavery, SA Baker, CA Shaw, W Li, HY Zoghbi Proceedings of the National Academy of Sciences 112 (17), 5509-5514, 2015 | 300 | 2015 |
| Proinflammatory role for let-7 microRNAS in experimental asthma S Polikepahad, JM Knight, AO Naghavi, T Oplt, CJ Creighton, C Shaw, ... Journal of Biological Chemistry 285 (39), 30139-30149, 2010 | 296 | 2010 |
| Parental somatic mosaicism is underrecognized and influences recurrence risk of genomic disorders IM Campbell, BO Yuan, C Robberecht, R Pfundt, P Szafranski, ... The American Journal of Human Genetics 95 (2), 173-182, 2014 | 285 | 2014 |
Sau W CheungProfessor of Molecular and Human Genetics, Baylor College of MedicineAdresse e-mail validée de bcm.edu