Carlos Cruchaga

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David HoltzmanWashington University in St. LouisAdresse e-mail validée de neuro.wustl.edu
Oscar HarariHelen C. Kurtz Associate Professor of Neurology, The Ohio State UniversityAdresse e-mail validée de osumc.edu
Bruno A. Benitez, MDAssistant Professor of Neurology, Harvard Medical School - Beth Israel Deaconess Medical CenterAdresse e-mail validée de bidmc.harvard.edu
Celeste M KarchProfessor of Psychiatry, Washington University in St LouisAdresse e-mail validée de wustl.edu
Randall BatemanWashington University in St. LouisAdresse e-mail validée de wustl.edu
John BuddeResearch Lab Manager, Washington University in St. LouisAdresse e-mail validée de wustl.edu
John KauwePresident, Brigham Young University–Hawaii; Professor of Biology, Brigham Young UniversityAdresse e-mail validée de byu.edu
Laura Ibáñez LladoAssistant Professor, Washington University in Saint LouisAdresse e-mail validée de wustl.edu
Jorge L. Del-AguilaAssociate Principal ScientistAdresse e-mail validée de astrazeneca.com
Maria Victoria FernandezFundacio ACE Institut de Neurosciencies AplicadesAdresse e-mail validée de fundacioace.org
Yuetiva Robles (Deming)University of Wisconsin - MadisonAdresse e-mail validée de wisc.edu
Richard MayeuxChair and Professor of Neurology, Director of the Taub Institute for Research on Alzheimer's DiseaseAdresse e-mail validée de columbia.edu
Pau PastorAssociate ProfessorAdresse e-mail validée de unav.es
Andrew SingletonNational Institute on AgingAdresse e-mail validée de mail.nih.gov
Rita GuerreiroVan Andel Research InstituteAdresse e-mail validée de vai.org
Jose BrasRegeneron Genetics Center, Regeneron PharmaceuticalsAdresse e-mail validée de regeneron.com
Sheng Chih JinAssistant Professor of Genetics at Washington University School of MedicineAdresse e-mail validée de wustl.edu
Ekaterina RogaevaTanz-CRND, University of TorontoAdresse e-mail validée de utoronto.ca
Kevin MorganProfessor University of NottinghamAdresse e-mail validée de nottingham.ac.uk
Perry RidgeAssociate Professor of Biology and Neuroscience, Brigham Young UniversityAdresse e-mail validée de byu.edu

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Carlos Cruchaga

Professor. NeuroGenomics and Informatics Center Director

Adresse e-mail validée de wustl.edu - Page d'accueil

Neurogenomics quantitative traits genetics single cell RNA-seq neurodegeneration Alzheimer disease


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013	4768	2013
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009	3439	2009
TREM2 variants in Alzheimer's disease R Guerreiro, A Wojtas, J Bras, M Carrasquillo, E Rogaeva, E Majounie, ... New England Journal of Medicine 368 (2), 117-127, 2013	3318	2013
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019	2580	2019
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011	2287	2011
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011	2244	2011
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018	1485	2018
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance JM Castellano, J Kim, FR Stewart, H Jiang, RB DeMattos, BW Patterson, ... Science translational medicine 3 (89), 89ra57-89ra57, 2011	1476	2011
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ... Nature genetics 50 (4), 524-537, 2018	1462	2018
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy Y Shi, K Yamada, SA Liddelow, ST Smith, L Zhao, W Luo, RM Tsai, ... Nature 549 (7673), 523-527, 2017	1120	2017
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017	983	2017
OASIS-3: longitudinal neuroimaging, clinical, and cognitive dataset for normal aging and Alzheimer disease PJ LaMontagne, TLS Benzinger, JC Morris, S Keefe, R Hornbeck, ... medrxiv, 2019.12. 13.19014902, 2019	788	2019
Alzheimer’s disease genetics: from the bench to the clinic CM Karch, C Cruchaga, AM Goate Neuron 83 (1), 11-26, 2014	550	2014
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease C Cruchaga, CM Karch, SC Jin, BA Benitez, Y Cai, R Guerreiro, O Harari, ... Nature 505 (7484), 550-554, 2014	542	2014
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease L Jones, PA Holmans, ML Hamshere, D Harold, V Moskvina, D Ivanov, ... PloS one 5 (11), e13950, 2010	468	2010
Common polygenic variation enhances risk prediction for Alzheimer’s disease V Escott-Price, R Sims, C Bannister, D Harold, M Vronskaya, E Majounie, ... Brain 138 (12), 3673-3684, 2015	462	2015
Frontotemporal dementia and its subtypes: a genome-wide association study R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ... The Lancet Neurology 13 (7), 686-699, 2014	429	2014
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease C Cruchaga, JSK Kauwe, O Harari, SC Jin, Y Cai, CM Karch, BA Benitez, ... Neuron 78 (2), 256-268, 2013	422	2013
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis DC Whitcomb, J LaRusch, AM Krasinskas, L Klei, JP Smith, RE Brand, ... Nature genetics 44 (12), 1349-1354, 2012	417	2012
Expression of novel Alzheimer’s disease risk genes in control and Alzheimer’s disease brains CM Karch, AT Jeng, P Nowotny, J Cady, C Cruchaga, AM Goate PloS one 7 (11), e50976, 2012	402	2012

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