Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform A Zarrinpar, DK Lee, A Silva, N Datta, T Kee, C Eriksen, K Weigle, ... Science Translational Medicine 8 (333), 333ra49-333ra49, 2016 | 154 | 2016 |
Mechanism-independent optimization of combinatorial nanodiamond and unmodified drug delivery using a phenotypically driven platform technology H Wang, DK Lee, KY Chen, JY Chen, K Zhang, A Silva, CM Ho, D Ho ACS nano 9 (3), 3332-3344, 2015 | 136 | 2015 |
Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP) MBMA Rashid, TB Toh, L Hooi, A Silva, Y Zhang, PF Tan, AL Teh, ... Science translational medicine 10 (453), eaan0941, 2018 | 118 | 2018 |
Output-driven feedback system control platform optimizes combinatorial therapy of tuberculosis using a macrophage cell culture model A Silva, BY Lee, DL Clemens, T Kee, X Ding, CM Ho, MA Horwitz Proceedings of the national academy of sciences 113 (15), E2172-E2179, 2016 | 93 | 2016 |
Drug regimens identified and optimized by output-driven platform markedly reduce tuberculosis treatment time BY Lee, DL Clemens, A Silva, BJ Dillon, S Masleša-Galić, S Nava, X Ding, ... Nature communications 8 (1), 1-11, 2017 | 74 | 2017 |
Identification and optimization of combinatorial glucose metabolism inhibitors in hepatocellular carcinomas MB Mohd Abdul Rashid, TB Toh, A Silva, L Nurrul Abdullah, CM Ho, D Ho, ... Journal of laboratory automation 20 (4), 423-437, 2015 | 46 | 2015 |
Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs DL Clemens, BY Lee, A Silva, BJ Dillon, S Masleša-Galić, S Nava, X Ding, ... PLOS ONE 14 (5), e0215607, 2019 | 34 | 2019 |
Multi-drug therapies for tuberculosis treatment CM Ho, DL Clemens, BYL Clemens, MA Horwitz, AMS Vite, T Kee, ... US Patent App. 10/080,749, 2018 | 23* | 2018 |
Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility BY Lee, DL Clemens, A Silva, BJ Dillon, S Masleša-Galić, S Nava, CM Ho, ... PloS one 13 (11), e0207469, 2018 | 20 | 2018 |
When Medicine Meets Engineering—Paradigm Shifts in Diagnostics and Therapeutics H Wang, A Silva, CM Ho Diagnostics 3 (1), 126-154, 2013 | 7 | 2013 |
Phenotypic personalized medicine: adaptive optimization of patient-specific combination therapy D Ho, CM Ho, A Zarrinpar, DK Lee, AMS Vite, N DATTA US Patent App. 15/558,983, 2019 | 5 | 2019 |
Multi-drug therapies for tuberculosis treatment CM Ho, DL Clemens, BYL Clemens, MA Horwitz, AMS Vite, T Kee, ... US Patent 10,576,079, 2020 | 1 | 2020 |
Improved drug combinations for drug-resistant and drug-sensitive multiple myeloma D Ho, CM Ho, AMS Vite, K Zhang, EKH CHOW, TB TOH, WJ CHNG, ... US Patent App. 15/571,457, 2019 | 1 | 2019 |
Multi-drug therapies for tuberculosis treatment CM Ho, DL Clemens, BYL Clemens, MA Horwitz, AMS Vite, T Kee, ... US Patent 10,080,749, 2018 | 1 | 2018 |
Phenotypic Personalized Medicine: Mechanism-Independent Convergence Into Target Serum Tacrolimus Levels for Optimized Liver Transplant Immunosuppression A Zarrinpar, A Silva, DK Lee, N Datta, CM Ho, D Ho AMERICAN JOURNAL OF TRANSPLANTATION 15, 2015 | 1 | 2015 |
Spatial redistribution of nano-particles using electrokinetic micro-focuser DE Garcia, A Silva, CM Ho Instrumentation, Metrology, and Standards for Nanomanufacturing 6648, 66480V, 2007 | 1 | 2007 |
Globally optimizing therapeutic combinations against bortezomib-resistant multiple myeloma using a quantitative parabolic optimization platform M Rashid, TB Toh, L Hooi, A Silva, Y Zhang, N Karnani, S Jha, CM Ho, ... Cancer Research 78 (13 Supplement), 5818-5818, 2018 | | 2018 |
1681PGlobally optimizing therapeutic combinations against bortezomib-resistant multiple myeloma using a quantitative parabolic optimization platform (QPOP) M Rashid, TB Toh, NL Abdullah, A Silva, Y Zhang, PF Tan, AL Teh, ... Annals of Oncology 28 (suppl_5), 2017 | | 2017 |
Identification and optimization of combinatorial glucose metabolism inhibitors in hepatocellular carcinomas MB Mohd Abdul Rashid, TB Toh, A Silva, L Nurrul Abdullah, CM Ho, D Ho, ... Journal of laboratory automation 20 (4), 423-437, 2015 | | 2015 |
Spatial redistribution of nano-particles using electrokinetic micro-focuser [6648-31] DE Garcia, A Silva, C Ho PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING 6648, 6648, 2007 | | 2007 |