Suivre
Shenyou Nie
Shenyou Nie
Professor of Medicinal Chemistry, Chongqing Medical University
Adresse e-mail validée de cqmu.edu.cn
Titre
Citée par
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Année
Discovery, X-ray crystallography and antiviral activity of allosteric inhibitors of flavivirus NS2B-NS3 protease
Y Yao, T Huo, YL Lin, S Nie, F Wu, Y Hua, J Wu, AR Kneubehl, MB Vogt, ...
Journal of the American Chemical Society 141 (17), 6832-6836, 2019
1182019
Total synthesis of nucleoside antibiotic A201A
S Nie, W Li, B Yu
Journal of the American Chemical Society 136 (11), 4157-4160, 2014
812014
Signaling pathway and small-molecule drug discovery of FGFR: A comprehensive review
J Zheng, W Zhang, L Li, Y He, Y Wei, Y Dang, S Nie, Z Guo
Frontiers in chemistry 10, 860985, 2022
512022
Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of in Vitro Splicing Inhibition
AK Ghosh, AM Veitschegger, S Nie, N Relitti, AJ MacRae, MS Jurica
The Journal of organic chemistry 83 (9), 5187-5198, 2018
362018
Synthesis, Structure–Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B–NS3 Protease
S Nie, Y Yao, F Wu, X Wu, J Zhao, Y Hua, J Wu, T Huo, YL Lin, ...
Journal of medicinal chemistry 64 (5), 2777-2800, 2021
342021
Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease
S Nie, J Zhao, X Wu, Y Yao, F Wu, YL Lin, X Li, AR Kneubehl, MB Vogt, ...
European journal of medicinal chemistry 225, 113767, 2021
272021
Discovery, structure–activity relationship, and biological activity of histone-competitive inhibitors of histone acetyltransferases P300/CBP
F Wu, Y Hua, S Kaochar, S Nie, YL Lin, Y Yao, J Wu, X Wu, X Fu, R Schiff, ...
Journal of medicinal chemistry 63 (9), 4716-4731, 2020
272020
Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth
F Wu, S Nie, Y Yao, T Huo, X Li, X Wu, J Zhao, YL Lin, Y Zhang, Q Mo, ...
Theranostics 11 (17), 8172, 2021
212021
A class of disulfide compounds suppresses ferroptosis by stabilizing GPX4
JP Liu, SY Cen, Z Xue, TX Wang, Y Gao, J Zheng, C Zhang, J Hu, S Nie, ...
ACS Chemical Biology 17 (12), 3389-3406, 2022
172022
Structure-activity relationship and antitumor activity of 1, 4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP
S Nie, F Wu, J Wu, X Li, C Zhou, Y Yao, Y Song
European journal of medicinal chemistry 237, 114407, 2022
102022
Deacylative arylation and alkynylation of unstrained ketones
B Zhang, H Bai, B Zhan, K Wei, S Nie, X Zhang
Science Advances 10 (17), eado0225, 2024
82024
Rapid access to C2-quaternary 3-methyleneindolines via base-mediated post-Ugi Conia-ene cyclization
S Zhao, Y He, F Gao, Y Wei, J Zhang, M Chen, Y Gao, Y Zhang, JY Liu, ...
Chemical Communications 59 (21), 3099-3102, 2023
72023
An unexpected rearrangement of pent-4-enofuranosides to cyclopentanones upon hydrogenolysis of the anomeric benzyl group
S Nie, X Chen, Y Ma, W Li, B Yu
Carbohydrate Research 432, 36-40, 2016
62016
[4+ 2] Cyclization or Lossen Rearrangement: Rhodium-Catalyzed Divergent Synthesis of Carboline Derivatives with Anticancer Activity
L Lv, J Zheng, Y Xiao, D Ni, Z Luo, Y Gao, Y Wei, Y He, S Nie
Organic Letters, 2024
52024
Green synthesis for diverse bioactive benzo-fused spiroindolines through DBU-catalysed post-Ugi double cyclization
S Zhao, M Chen, W Zhou, D Ni, Z Li, S Nie, Y He
Chemical Communications 60 (41), 5455-5458, 2024
22024
Rhodium-catalysed homo-coupling of terminal alkynes: divergent synthesis of bioactive 1, 3-diynes and conjugated enediynes
Y Xiao, L Lv, N Luo, P Zhao, Y Chen, Z Luo, H Yin, Y He, S Nie
New Journal of Chemistry 48 (16), 7517-7523, 2024
22024
Design, synthesis and anticancer activity of β-carboline based pseudo-natural products by inhibiting AKT/mTOR signaling pathway
L Lv, K Song, Y Xiao, J Zheng, W Zhang, L Li, Y Wei, H Chen, Y He, Z Guo, ...
Bioorganic Chemistry 151, 107648, 2024
12024
Discovery and optimization of 1, 2, 4-triazole derivatives as novel ferroptosis inhibitors
J Zhang, F Lin, Y Xiao, SY Cen, BW Wan, X Li, Y Zhao, Y He, HX Yuan, ...
European Journal of Medicinal Chemistry 284, 117192, 2025
2025
Discovery of novel benzo [b][1, 4] oxazine derivatives as ferroptosis inhibitors
BW Wan, W Liu, Y Xiao, L Lv, X Li, F Lin, Y Zhao, Y He, S Nie, X Yang, ...
Bioorganic Chemistry, 108201, 2025
2025
Design, Synthesis, and Biological Evaluation of 3-Amino-pyrazine-2-carboxamide Derivatives as Novel FGFR Inhibitors
J Zheng, W Zhang, D Ni, S Zhao, Y He, J Hu, L Li, Y Dang, Z Guo, S Nie
ACS Medicinal Chemistry Letters 15 (11), 2019-2031, 2024
2024
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