| High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1715 | 2015 |
| High-density proximity mapping reveals the subcellular organization of mRNA-associated granules and bodies JY Youn, WH Dunham, SJ Hong, JDR Knight, M Bashkurov, GI Chen, ... Molecular cell 69 (3), 517-532. e11, 2018 | 726 | 2018 |
| Functional enhancers shape extrachromosomal oncogene amplifications AR Morton, N Dogan-Artun, ZJ Faber, G MacLeod, CF Bartels, MS Piazza, ... Cell 179 (6), 1330-1341. e13, 2019 | 292 | 2019 |
| Gradient of developmental and injury response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity LM Richards, OKN Whitley, G MacLeod, FMG Cavalli, FJ Coutinho, ... Nature Cancer 2 (2), 157-173, 2021 | 243 | 2021 |
| Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ... Cell reports 27 (3), 971-986. e9, 2019 | 229 | 2019 |
| Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ... Nature communications 11 (1), 3701, 2020 | 180 | 2020 |
| Metabolic regulation of the epigenome drives lethal infantile ependymoma KA Michealraj, SA Kumar, LJY Kim, FMG Cavalli, D Przelicki, JB Wojcik, ... Cell 181 (6), 1329-1345. e24, 2020 | 122 | 2020 |
| Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells N Rajakulendran, KJ Rowland, HJ Selvadurai, M Ahmadi, NI Park, ... Genes & development 33 (9-10), 498-510, 2019 | 110 | 2019 |
| Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival P Guilhamon, C Chesnelong, MM Kushida, A Nikolic, D Singhal, ... Elife 10, e64090, 2021 | 78 | 2021 |
| A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy R Chidiac, M Abedin, G Macleod, A Yang, PE Thibeault, LL Blazer, ... EMBO Molecular Medicine 13 (7), e13977, 2021 | 44 | 2021 |
| SAPCD2 controls spindle orientation and asymmetric divisions by negatively regulating the Gαi-LGN-NuMA ternary complex CWN Chiu, C Monat, M Robitaille, M Lacomme, AM Daulat, G Macleod, ... Developmental cell 36 (1), 50-62, 2016 | 41 | 2016 |
| The application of proteomic approaches to the study of mammalian spermatogenesis and sperm function G MacLeod, S Varmuza The FEBS Journal 280 (22), 5635-5651, 2013 | 34 | 2013 |
| Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes X Wang, Z Gong, T Wang, J Law, X Chen, S Wanggou, J Wang, B Ying, ... Science Advances 9 (13), eade5321, 2023 | 30 | 2023 |
| Identification of potentially damaging amino acid substitutions leading to human male infertility A Kuzmin, K Jarvi, K Lo, L Spencer, GYC Chow, G Macleod, Q Wang, ... Biology of reproduction 81 (2), 319-326, 2009 | 28 | 2009 |
| New candidate targets of protein phosphatase‐1c‐gamma‐2 in mouse testis revealed by a differential phosphoproteome analysis H Henderson, G Macleod, C Hrabchak, S Varmuza International journal of andrology 34 (4pt1), 339-351, 2011 | 18 | 2011 |
| Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ AM Opaluch, M Schneider, C Chiang, QT Nguyen, AM Maestre, ... PLoS One 9 (2), e89284, 2014 | 16 | 2014 |
| PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis G MacLeod, P Shang, GT Booth, LA Mastropaolo, N Manafpoursakha, ... Reproduction 147 (1), 1-12, 2014 | 16 | 2014 |
| Tandem affinity purification in transgenic mouse embryonic stem cells identifies DDOST as a novel PPP1CC2 interacting protein G MacLeod, S Varmuza Biochemistry 51 (48), 9678-9688, 2012 | 15 | 2012 |
| Comparative phosphoproteomic analysis of the mouse testis reveals changes in phosphopeptide abundance in response to Ppp1cc deletion G MacLeod, P Taylor, L Mastropaolo, S Varmuza EuPA Open Proteomics 2, 1-16, 2014 | 7 | 2014 |
| The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma T Houles, J Boucher, G Lavoie, G MacLeod, S Lin, S Angers, PP Roux Cell Death Discovery 9 (1), 459, 2023 | 4 | 2023 |