Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes JE Neggers, B Kwanten, T Dierckx, H Noguchi, A Voet, L Bral, K Minner, ... Nature Communications 9 (1), 502, 2018 | 118 | 2018 |
Inflammatory gene expression profile and defective interferon‐γ and granzyme K in natural killer cells from systemic juvenile idiopathic arthritis patients K Put, J Vandenhaute, A Avau, A van Nieuwenhuijze, E Brisse, T Dierckx, ... Arthritis & Rheumatology 69 (1), 213-224, 2017 | 93 | 2017 |
Low eukaryotic viral richness is associated with faecal microbiota transplantation success in patients with UC N Conceição-Neto, W Deboutte, T Dierckx, K Machiels, J Wang, KC Yinda, ... Gut 67 (8), 1558-1559, 2018 | 71 | 2018 |
Systems approach reveals nuclear factor erythroid 2-related factor 2/protein kinase R crosstalk in human cutaneous leishmaniasis ÁC Vivarini, TC Calegari-Silva, AM Saliba, VS Boaventura, ... Frontiers in immunology 8, 1127, 2017 | 46 | 2017 |
An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans M Delgobo, DAGB Mendes, E Kozlova, EL Rocha, GF Rodrigues-Luiz, ... elife 8, e47013, 2019 | 44 | 2019 |
ISG15-induced IL-10 is a novel anti-inflammatory myeloid axis disrupted during active tuberculosis PF Dos Santos, J Van Weyenbergh, M Delgobo, D Oliveira Patricio, ... The Journal of Immunology 200 (4), 1434-1442, 2018 | 44 | 2018 |
GlycA, a nuclear magnetic resonance spectroscopy measure for protein glycosylation, is a viable biomarker for disease activity in IBD T Dierckx, B Verstockt, S Vermeire, J van Weyenbergh Journal of Crohn's and Colitis 13 (3), 389-394, 2019 | 41 | 2019 |
Pathogen transcriptional profile in nasopharyngeal aspirates of children with acute respiratory tract infection KF Fukutani, CM Nascimento-Carvalho, W Van der Gucht, E Wollants, ... Journal of Clinical Virology 69, 190-196, 2015 | 29 | 2015 |
IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients T Dierckx, R Khouri, SM Menezes, D Decanine, L Farre, A Bittencourt, ... Blood cancer journal 7 (1), e519-e519, 2017 | 26 | 2017 |
Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-β Response in HTLV-1-Associated … FE Leal, SM Menezes, EAS Costa, PM Brailey, L Gama, AC Segurado, ... Frontiers in microbiology 9, 985, 2018 | 21 | 2018 |
Detection of natural resistance-associated substitutions by ion semiconductor technology in HCV1b positive, direct-acting antiviral agents-naïve patients N Marascio, G Pavia, A Strazzulla, T Dierckx, L Cuypers, B Vrancken, ... International Journal of Molecular Sciences 17 (9), 1416, 2016 | 20 | 2016 |
The metabolic fingerprint of COVID-19 severity T Dierckx, J Van Elslande, H Salmela, B Decru, E Wauters, J Gunst, ... MedRxiv, 2020.11. 09.20228221, 2020 | 19 | 2020 |
A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation SM Menezes, FE Leal, T Dierckx, R Khouri, D Decanine, G Silva-Santos, ... Frontiers in immunology 8, 97, 2017 | 18 | 2017 |
Decreased RORC expression and downstream signaling in HTLV‐1‐associated adult T‐cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for … K Subramanian, T Dierckx, R Khouri, SM Menezes, H Kagdi, GP Taylor, ... International Journal of Cancer 144 (7), 1664-1675, 2019 | 17 | 2019 |
In situ Immune Signatures and Microbial Load at the Nasopharyngeal Interface in Children With Acute Respiratory Infection KF Fukutani, CM Nascimento-Carvalho, ML Bouzas, JR Oliveira, A Barral, ... Frontiers in Microbiology 9, 2475, 2018 | 17 | 2018 |
A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients R Khouri, G Silva-Santos, T Dierckx, SM Menezes, D Decanine, K Theys, ... Oncoimmunology 7 (5), e1426423, 2018 | 16 | 2018 |
enAsCas12a enables CRISPR-directed evolution to screen for functional drug resistance mutations in sequences inaccessible to SpCas9 JE Neggers, M Jacquemyn, T Dierckx, BP Kleinstiver, HJ Thibaut, ... Molecular Therapy 29 (1), 208-224, 2021 | 14 | 2021 |
Urinary peptides as potential non-invasive biomarkers for lupus nephritis: results of the peptidu-LUP study M Tailliar, JP Schanstra, T Dierckx, B Breuil, G Hanouna, N Charles, ... Journal of Clinical Medicine 10 (8), 1690, 2021 | 13 | 2021 |
Serum GlycA level is elevated in active systemic lupus erythematosus and correlates to disease activity and lupus nephritis severity T Dierckx, L Chiche, L Daniel, B Lauwerys, J Van Weyenbergh, ... Journal of clinical medicine 9 (4), 970, 2020 | 12 | 2020 |
Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation T Assone, SM Menezes, F de Toledo Gonçalves, VA Folgosi, ... Journal of neuroinflammation 19 (1), 293, 2022 | 10 | 2022 |