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Early stage NSCLC—challenges to implementing ctDNA-based screening and MRD detection

C Abbosh, NJ Birkbak, C Swanton

Nature Reviews Clinical Oncology 15 (9), 577-586, 2018

Exigences : Cancer Research UK, UK Medical Research Council, National Institute for …

Targeting chromosomal instability and tumour heterogeneity in HER2‐positive breast cancer

RA Burrell, N Juul, SR Johnston, JS Reis‐Filho, Z Szallasi, C Swanton

Journal of cellular biochemistry 111 (4), 782-790, 2010

Exigences : US National Institutes of Health, Cancer Research UK

Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer

R Roylance, D Endesfelder, M Jamal-Hanjani, RA Burrell, P Gorman, ...

Breast cancer research and treatment 148, 221-229, 2014

Exigences : Cancer Research UK, UK Medical Research Council, National Institute for …

Disponibles quelque part : 87

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...

Science 351 (6280), 1463-1469, 2016

Exigences : US National Institutes of Health, Cancer Research UK, National Institute for …

[HTML] nejm.org

Tracking the evolution of non–small-cell lung cancer

M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...

New England Journal of Medicine 376 (22), 2109-2121, 2017

Exigences : Cancer Research UK, UK Medical Research Council, National Institute for …

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...

Nature 545 (7655), 446-451, 2017

Exigences : US National Institutes of Health, Versus Arthritis, UK, Cancer Research UK …

[PDF] wiley.com

Artificial intelligence in cancer imaging: clinical challenges and applications

WL Bi, A Hosny, MB Schabath, ML Giger, NJ Birkbak, A Mehrtash, ...

CA: a cancer journal for clinicians 69 (2), 127-157, 2019

Exigences : US National Institutes of Health, Instituts de recherche en santé du Canada …

Chromosomal instability drives metastasis through a cytosolic DNA response

SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ...

Nature 553 (7689), 467-472, 2018

Exigences : US National Science Foundation, US Department of Defense, US National …

Allele-specific HLA loss and immune escape in lung cancer evolution

N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...

Cell 171 (6), 1259-1271. e11, 2017

Exigences : Versus Arthritis, UK, Cancer Research UK, UK Medical Research Council …

[PDF] nih.gov

Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer

DP Silver, AL Richardson, AC Eklund, ZC Wang, Z Szallasi, Q Li, N Juul, ...

Journal of clinical oncology 28 (7), 1145-1153, 2010

Exigences : US National Institutes of Health

[HTML] thelancet.com

Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis

S Turajlic, K Litchfield, H Xu, R Rosenthal, N McGranahan, JL Reading, ...

The lancet oncology 18 (8), 1009-1021, 2017

Exigences : Cancer Research UK, UK Medical Research Council, National Institute for …

Neoantigen-directed immune escape in lung cancer evolution

R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ...

Nature 567 (7749), 479-485, 2019

Exigences : US National Institutes of Health, Danish Council for Strategic Research …

[HTML] sciencedirect.com

Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data

F Favero, T Joshi, AM Marquard, NJ Birkbak, M Krzystanek, Q Li, ...

Annals of Oncology 26 (1), 64-70, 2015

Exigences : Danish Council for Independent Research

[PDF] nih.gov

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

N McGranahan, F Favero, EC De Bruin, NJ Birkbak, Z Szallasi, ...

Science translational medicine 7 (283), 283ra54-283ra54, 2015

Exigences : Cancer Research UK, National Institute for Health Research, UK, European …

Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal

S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ...

Cell 173 (3), 595-610. e11, 2018

Exigences : Cancer Research UK, UK Medical Research Council, National Institute for …

[PDF] nih.gov

Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents

NJ Birkbak, ZC Wang, JY Kim, AC Eklund, Q Li, R Tian, C Bowman-Colin, ...

Cancer discovery 2 (4), 366-375, 2012

Exigences : US National Institutes of Health

Fc effector function contributes to the activity of human anti-CTLA-4 antibodies

FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...

Cancer cell 33 (4), 649-663. e4, 2018

Exigences : Blood Cancer UK, Cancer Research UK, UK Medical Research Council, National …

Inconsistency in large pharmacogenomic studies

B Haibe-Kains, N El-Hachem, NJ Birkbak, AC Jin, AH Beck, HJWL Aerts, ...

Nature 504 (7480), 389-393, 2013

Exigences : US National Institutes of Health

Chromosomal instability confers intrinsic multidrug resistance

AJX Lee, D Endesfelder, AJ Rowan, A Walther, NJ Birkbak, PA Futreal, ...

Cancer research 71 (5), 1858-1870, 2011

Exigences : Cancer Research UK