| Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na (+)-Ca2+ exchanger PK Stys, SG Waxman, BR Ransom Journal of Neuroscience 12 (2), 430-439, 1992 | 844 | 1992 |
| Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis BD Trapp, PK Stys The Lancet Neurology 8 (3), 280-291, 2009 | 792 | 2009 |
| Will the real multiple sclerosis please stand up? PK Stys, GW Zamponi, J Van Minnen, JJG Geurts Nature Reviews Neuroscience 13 (7), 507-514, 2012 | 704 | 2012 |
| Inefficient clearance of myelin debris by microglia impairs remyelinating processes A Lampron, A Larochelle, N Laflamme, P Préfontaine, MM Plante, ... Journal of Experimental Medicine 212 (4), 481-495, 2015 | 630 | 2015 |
| NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia I Micu, Q Jiang, E Coderre, A Ridsdale, L Zhang, J Woulfe, X Yin, ... Nature 439 (7079), 988-992, 2006 | 584 | 2006 |
| Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels JA Wolf, PK Stys, T Lusardi, D Meaney, DH Smith Journal of Neuroscience 21 (6), 1923-1930, 2001 | 584 | 2001 |
| Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial MD Hill, M Goyal, BK Menon, RG Nogueira, RA McTaggart, AM Demchuk, ... The Lancet 395 (10227), 878-887, 2020 | 564 | 2020 |
| Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter S Li, PK Stys Journal of Neuroscience 20 (3), 1190-1198, 2000 | 405 | 2000 |
| Anoxic and ischemic injury of myelinated axons in CNS white matter: from mechanistic concepts to therapeutics PK Stys Journal of Cerebral Blood Flow & Metabolism 18 (1), 2-25, 1998 | 394 | 1998 |
| General mechanisms of axonal damage and its prevention PK Stys Journal of the neurological sciences 233 (1-2), 3-13, 2005 | 382 | 2005 |
| Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data L San Román, BK Menon, J Blasco, M Hernández-Pérez, A Dávalos, ... The Lancet Neurology 17 (10), 895-904, 2018 | 381 | 2018 |
| Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis … BCV Campbell, CBLM Majoie, GW Albers, BK Menon, N Yassi, G Sharma, ... The Lancet Neurology 18 (1), 46-55, 2019 | 365 | 2019 |
| White matter injury mechanisms PK Stys Current molecular medicine 4 (2), 113-130, 2004 | 327 | 2004 |
| Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport S Li, GAR Mealing, P Morley, PK Stys The Journal of neuroscience 19 (14), RC16, 1999 | 325 | 1999 |
| Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non … BK Menon, BH Buck, N Singh, Y Deschaintre, MA Almekhlafi, SB Coutts, ... The Lancet 400 (10347), 161-169, 2022 | 311 | 2022 |
| The axon: structure, function, and pathophysiology SG Waxman, JD Kocsis, PK Stys Oxford University Press, 1995 | 298 | 1995 |
| Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors H You, S Tsutsui, S Hameed, TJ Kannanayakal, L Chen, P Xia, ... Proceedings of the National Academy of Sciences 109 (5), 1737-1742, 2012 | 287 | 2012 |
| Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors A Iwata, PK Stys, JA Wolf, XH Chen, AG Taylor, DF Meaney, DH Smith Journal of neuroscience 24 (19), 4605-4613, 2004 | 282 | 2004 |
| Immunosenescence of microglia and macrophages: impact on the ageing central nervous system KS Rawji, MK Mishra, NJ Michaels, S Rivest, PK Stys, VW Yong Brain 139 (3), 653-661, 2016 | 271 | 2016 |
| Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons. PK Stys, H Sontheimer, BR Ransom, SG Waxman Proceedings of the National Academy of Sciences 90 (15), 6976-6980, 1993 | 264 | 1993 |
