| Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ... Science 324 (5928), 801-804, 2009 | 895 | 2009 |
| The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol. AE Belanger, GS Besra, ME Ford, K Mikusová, JT Belisle, PJ Brennan, ... Proceedings of the National Academy of Sciences 93 (21), 11919-11924, 1996 | 679 | 1996 |
| Biogenesis of the mycobacterial cell wall and the site of action of ethambutol K Mikusova, RA Slayden, GS Besra, PJ Brennan Antimicrobial agents and chemotherapy 39 (11), 2484-2489, 1995 | 441 | 1995 |
| Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of … K Mikušová, H Huang, T Yagi, M Holsters, D Vereecke, W D'Haeze, ... Journal of bacteriology 187 (23), 8020-8025, 2005 | 256 | 2005 |
| Identification of a small molecule with activity against drug-resistant and persistent tuberculosis F Wang, D Sambandan, R Halder, J Wang, SM Batt, B Weinrick, I Ahmad, ... Proceedings of the National Academy of Sciences 110 (27), E2510-E2517, 2013 | 255 | 2013 |
| Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis: PimA is essential for growth of mycobacteria J Korduláková, M Gilleron, K Mikus̃ová, G Puzo, PJ Brennan, B Gicquel, ... Journal of Biological Chemistry 277 (35), 31335-31344, 2002 | 222 | 2002 |
| Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase DprE1 C Trefzer, H Škovierová, S Buroni, A Bobovská, S Nenci, E Molteni, ... Journal of the American Chemical Society 134 (2), 912-915, 2012 | 215 | 2012 |
| Recognition of multiple effects of ethambutol on metabolism of mycobacterial cell envelope L Deng, K Mikusová, KG Robuck, M Scherman, PJ Brennan, MR McNeil Antimicrobial Agents and Chemotherapy 39 (3), 694-701, 1995 | 214 | 1995 |
| Synthesis of the Arabinose Donor. beta.-D-Arabinofuranosyl-1-monophosphoryldecaprenol, development of a basic arabinosyl-transferase assay, and identification of ethambutol as … RE Lee, K Mikusova, PJ Brennan, GS Besra Journal of the American Chemical Society 117 (48), 11829-11832, 1995 | 197 | 1995 |
| Biosynthesis of the Linkage Region of the Mycobacterial Cell Wall (∗) K Mikusová, M Mikus, GS Besra, I Hancock, PJ Brennan Journal of Biological Chemistry 271 (13), 7820-7828, 1996 | 185 | 1996 |
| DprE1 is a vulnerable tuberculosis drug target due to its cell wall localization M Brecik, I Centárová, R Mukherjee, GS Kolly, S Huszár, A Bobovská, ... ACS chemical biology 10 (7), 1631-1636, 2015 | 161 | 2015 |
| Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria ME Guerin, J Kordulakova, F Schaeffer, Z Svetlikova, A Buschiazzo, ... Journal of Biological Chemistry 282 (28), 20705-20714, 2007 | 160 | 2007 |
| Biosynthesis of the galactan component of the mycobacterial cell wall K Mikušová, T Yagi, R Stern, MR McNeil, GS Besra, DC Crick, ... Journal of Biological Chemistry 275 (43), 33890-33897, 2000 | 160 | 2000 |
| Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis: inhibition of arabinan biosynthesis by ethambutol KH Khoo, E Douglas, P Azadi, JM Inamine, GS Besra, K Mikušová, ... Journal of Biological Chemistry 271 (45), 28682-28690, 1996 | 140 | 1996 |
| Galactosyl transferases in mycobacterial cell wall synthesis M Belánová, P Dianišková, PJ Brennan, GC Completo, NL Rose, ... Journal of bacteriology 190 (3), 1141-1145, 2008 | 136 | 2008 |
| Development of 3, 5-dinitrobenzylsulfanyl-1, 3, 4-oxadiazoles and thiadiazoles as selective antitubercular agents active against replicating and nonreplicating Mycobacterium … G Karabanovich, J Zemanová, T Smutný, R Székely, M Šarkan, ... Journal of medicinal chemistry 59 (6), 2362-2380, 2016 | 128 | 2016 |
| Interaction of Human Mannose-Binding Protein with Mycobacterium avium VY Polotsky, JT Belisle, K Mikusova, RAB Ezekowitz, KA Joiner Journal of Infectious Diseases 175 (5), 1159-1168, 1997 | 120 | 1997 |
| Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of Mycobacterium species J Korduláková, M Gilleron, G Puzo, PJ Brennan, B Gicquel, K Mikusová, ... Journal of Biological Chemistry 278 (38), 36285-36295, 2003 | 115 | 2003 |
| Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ... Molecular microbiology 77 (5), 1172-1185, 2010 | 104 | 2010 |
| The complex mechanism of antimycobacterial action of 5-fluorouracil V Singh, M Brecik, R Mukherjee, JC Evans, Z Svetlíková, J Blaško, ... Chemistry & biology 22 (1), 63-75, 2015 | 99 | 2015 |
