| Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export P Lei, S Ayton, DI Finkelstein, L Spoerri, GD Ciccotosto, DK Wright, ... Nature medicine 18 (2), 291-295, 2012 | 661 | 2012 |
| The role of metallobiology and amyloid‐β peptides in Alzheimer’s disease BR Roberts, TM Ryan, AI Bush, CL Masters, JA Duce Journal of neurochemistry 120, 149-166, 2012 | 345 | 2012 |
| Glutathione peroxidase 4: a new player in neurodegeneration? BR Cardoso, DJ Hare, AI Bush, BR Roberts Molecular Psychiatry 22 (3), 328-335, 2017 | 286 | 2017 |
| Selenium, selenoproteins and neurodegenerative diseases BR Cardoso, BR Roberts, AI Bush, DJ Hare Metallomics 7 (8), 1213-1228, 2015 | 280 | 2015 |
| Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegansfor drug screening for Alzheimer’s disease G McColl, BR Roberts, TL Pukala, VB Kenche, CM Roberts, CD Link, ... Molecular neurodegeneration 7, 1-9, 2012 | 278 | 2012 |
| The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson’s disease LW Hung, VL Villemagne, L Cheng, NA Sherratt, S Ayton, AR White, ... Journal of Experimental Medicine 209 (4), 837-854, 2012 | 192 | 2012 |
| Oral treatment with CuII (atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, ... Journal of Neuroscience 34 (23), 8021-8031, 2014 | 188 | 2014 |
| Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS BR Roberts, JA Tainer, ED Getzoff, DA Malencik, SR Anderson, ... Journal of molecular biology 373 (4), 877-890, 2007 | 184 | 2007 |
| Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SODG93A mice co-expressing the Copper-Chaperone-for-SOD JR Williams, E Trias, PR Beilby, NI Lopez, EM Labut, CS Bradford, ... Neurobiology of disease 89, 1-9, 2016 | 164 | 2016 |
| Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease A Rembach, NG Faux, AD Watt, KK Pertile, RL Rumble, BO Trounson, ... Alzheimer's & Dementia 10 (1), 53-61, 2014 | 160 | 2014 |
| Biochemically-defined pools of amyloid-β in sporadic Alzheimer’s disease: correlation with amyloid PET BR Roberts, M Lind, AZ Wagen, A Rembach, T Frugier, QX Li, TM Ryan, ... Brain 140 (5), 1486-1498, 2017 | 154 | 2017 |
| The Caenorhabditis elegans Aβ1–42 model of Alzheimer disease predominantly expresses Aβ3–42 G McColl, BR Roberts, AP Gunn, KA Perez, DJ Tew, CL Masters, ... Journal of Biological Chemistry 284 (34), 22697-22702, 2009 | 150 | 2009 |
| Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization TM Ryan, J Caine, HDT Mertens, N Kirby, J Nigro, K Breheney, ... PeerJ 1, e73, 2013 | 134 | 2013 |
| Copper promotes the trafficking of the amyloid precursor protein KM Acevedo, YH Hung, AH Dalziel, QX Li, K Laughton, K Wikhe, ... Journal of Biological Chemistry 286 (10), 8252-8262, 2011 | 122 | 2011 |
| Trace element–protein interactions in endolymph from the inner ear of fish: implications for environmental reconstructions using fish otolith chemistry ORB Thomas, K Ganio, BR Roberts, SE Swearer Metallomics 9 (3), 239-249, 2017 | 117 | 2017 |
| An iron–dopamine index predicts risk of parkinsonian neurodegeneration in the substantia nigra pars compacta DJ Hare, P Lei, S Ayton, BR Roberts, R Grimm, JL George, DP Bishop, ... Chemical Science 5 (6), 2160-2169, 2014 | 116 | 2014 |
| Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson’s disease brain S Genoud, BR Roberts, AP Gunn, GM Halliday, SJG Lewis, HJ Ball, ... Metallomics 9 (10), 1447-1455, 2017 | 115 | 2017 |
| The neurobiology and age-related prevalence of the ε4 allele of apolipoprotein E in Alzheimer’s disease cohorts AL Heffernan, C Chidgey, P Peng, CL Masters, BR Roberts Journal of Molecular Neuroscience 60, 316-324, 2016 | 106 | 2016 |
| Supranutritional sodium selenate supplementation delivers selenium to the central nervous system: results from a randomized controlled pilot trial in Alzheimer’s disease BR Cardoso, BR Roberts, CB Malpas, L Vivash, S Genc, MM Saling, ... Neurotherapeutics 16, 192-202, 2019 | 104 | 2019 |
| Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans SA James, BR Roberts, DJ Hare, MD de Jonge, IE Birchall, NL Jenkins, ... Chemical science 6 (5), 2952-2962, 2015 | 102 | 2015 |
Ashley BushMassachusetts General Hospital, Florey Institute of Neuroscience & Mental HealthAdresse e-mail validée de helix.mgh.harvard.edu