Metabolomics-based methods for early disease diagnostics GAN Gowda, S Zhang, H Gu, V Asiago, N Shanaiah, D Raftery Expert review of molecular diagnostics 8 (5), 617-633, 2008 | 802 | 2008 |
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition H Sperber, J Mathieu, Y Wang, A Ferreccio, J Hesson, Z Xu, KA Fischer, ... Nature cell biology 17 (12), 1523-1535, 2015 | 448 | 2015 |
Defective branched-chain amino acid catabolism disrupts glucose metabolism and sensitizes the heart to ischemia-reperfusion injury T Li, Z Zhang, SC Kolwicz, L Abell, ND Roe, M Kim, B Zhou, Y Cao, ... Cell metabolism 25 (2), 374-385, 2017 | 373 | 2017 |
Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart DF Dai, PP Karunadharma, YA Chiao, N Basisty, D Crispin, EJ Hsieh, ... Aging cell 13 (3), 529-539, 2014 | 349 | 2014 |
EGFR signaling enhances aerobic glycolysis in triple-negative breast cancer cells to promote tumor growth and immune escape SO Lim, CW Li, W Xia, HH Lee, SS Chang, J Shen, JL Hsu, D Raftery, ... Cancer research 76 (5), 1284-1296, 2016 | 259 | 2016 |
ApoE4 impairs neuron-astrocyte coupling of fatty acid metabolism G Qi, Y Mi, X Shi, H Gu, RD Brinton, F Yin Cell reports 34 (1), 2021 | 247 | 2021 |
Colorectal cancer detection using targeted serum metabolic profiling J Zhu, D Djukovic, L Deng, H Gu, F Himmati, EG Chiorean, D Raftery Journal of proteome research 13 (9), 4120-4130, 2014 | 226 | 2014 |
Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis PA Carroll, D Diolaiti, L McFerrin, H Gu, D Djukovic, J Du, PF Cheng, ... Cancer cell 27 (2), 271-285, 2015 | 214 | 2015 |
Principal component analysis of urine metabolites detected by NMR and DESI–MS in patients with inborn errors of metabolism Z Pan, H Gu, N Talaty, H Chen, N Shanaiah, BE Hainline, RG Cooks, ... Analytical and bioanalytical chemistry 387, 539-549, 2007 | 210 | 2007 |
Statistical analysis and modeling of mass spectrometry-based metabolomics data B Xi, H Gu, H Baniasadi, D Raftery Mass spectrometry in metabolomics: methods and protocols, 333-353, 2014 | 184 | 2014 |
Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: application to the detection of … H Gu, Z Pan, B Xi, V Asiago, B Musselman, D Raftery Analytica chimica acta 686 (1-2), 57-63, 2011 | 174 | 2011 |
Glucose promotes cell growth by suppressing branched-chain amino acid degradation D Shao, O Villet, Z Zhang, SW Choi, J Yan, J Ritterhoff, H Gu, D Djukovic, ... Nature communications 9 (1), 2935, 2018 | 150 | 2018 |
Differentiation of maturity and quality of fruit using noninvasive extractive electrospray ionization quadrupole time-of-flight mass spectrometry H Chen, Y Sun, A Wortmann, H Gu, R Zenobi Analytical chemistry 79 (4), 1447-1455, 2007 | 144 | 2007 |
Monitoring diet effects via biofluids and their implications for metabolomics studies H Gu, H Chen, Z Pan, AU Jackson, N Talaty, B Xi, C Kissinger, C Duda, ... Analytical chemistry 79 (1), 89-97, 2007 | 132 | 2007 |
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts YA Chiao, SC Kolwicz, N Basisty, A Gagnidze, J Zhang, H Gu, D Djukovic, ... Aging (Albany NY) 8 (2), 314, 2016 | 127 | 2016 |
Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration Y Mi, G Qi, F Vitali, Y Shang, AC Raikes, T Wang, Y Jin, RD Brinton, H Gu, ... Nature metabolism 5 (3), 445-465, 2023 | 120 | 2023 |
Globally optimized targeted mass spectrometry: reliable metabolomics analysis with broad coverage H Gu, P Zhang, J Zhu, D Raftery Analytical chemistry 87 (24), 12355-12362, 2015 | 118 | 2015 |
Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy NL Reyes, GB Banks, M Tsang, D Margineantu, H Gu, D Djukovic, J Chan, ... Proceedings of the National Academy of Sciences 112 (2), 424-429, 2015 | 118 | 2015 |
Breast cancer detection using targeted plasma metabolomics P Jasbi, D Wang, SL Cheng, Q Fei, JY Cui, L Liu, Y Wei, D Raftery, H Gu Journal of chromatography B 1105, 26-37, 2019 | 107 | 2019 |
15N-CholamineA Smart Isotope Tag for Combining NMR- and MS-Based Metabolite Profiling F Tayyari, GAN Gowda, H Gu, D Raftery Analytical chemistry 85 (18), 8715-8721, 2013 | 107 | 2013 |