Deubiquitination and stabilization of PD-L1 by CSN5 SO Lim, CW Li, W Xia, JH Cha, LC Chan, Y Wu, SS Chang, WC Lin, ... Cancer cell 30 (6), 925-939, 2016 | 707 | 2016 |
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion JM Hsu, W Xia, YH Hsu, LC Chan, WH Yu, JH Cha, CT Chen, HW Liao, ... Nature communications 9 (1), 1908, 2018 | 387 | 2018 |
Blocking c-Met–mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors Y Du, H Yamaguchi, Y Wei, JL Hsu, HL Wang, YH Hsu, WC Lin, WH Yu, ... Nature medicine 22 (2), 194-201, 2016 | 250 | 2016 |
Immunological synapse predicts effectiveness of chimeric antigen receptor cells W Xiong, Y Chen, X Kang, Z Chen, P Zheng, YH Hsu, JH Jang, L Qin, ... Molecular Therapy 26 (4), 963-975, 2018 | 151 | 2018 |
Crystal structure of yeast cytosine deaminase: insights into enzyme mechanism and evolution TP Ko, JJ Lin, CY Hu, YH Hsu, AHJ Wang, SH Liaw Journal of Biological Chemistry 278 (21), 19111-19117, 2003 | 150 | 2003 |
CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer L Nie, Y Wei, F Zhang, YH Hsu, LC Chan, W Xia, B Ke, C Zhu, R Deng, ... Nature communications 10 (1), 5114, 2019 | 88 | 2019 |
AKT1 inhibits epithelial-to-mesenchymal transition in breast cancer through phosphorylation-dependent Twist1 degradation CW Li, W Xia, SO Lim, JL Hsu, L Huo, Y Wu, LY Li, CC Lai, SS Chang, ... Cancer research 76 (6), 1451-1462, 2016 | 85 | 2016 |
Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancer YH Hsu, J Yao, LC Chan, TJ Wu, JL Hsu, YF Fang, Y Wei, Y Wu, ... Cancer research 74 (17), 4822-4835, 2014 | 77 | 2014 |
Targeting PKCδ as a therapeutic strategy against heterogeneous mechanisms of EGFR inhibitor resistance in EGFR-mutant lung cancer PC Lee, YF Fang, H Yamaguchi, WJ Wang, TC Chen, X Hong, B Ke, ... Cancer cell 34 (6), 954-969. e4, 2018 | 70 | 2018 |
Oncogenic functions of Gli1 in pancreatic adenocarcinoma are supported by its PRMT1-mediated methylation Y Wang, JM Hsu, Y Kang, Y Wei, PC Lee, SJ Chang, YH Hsu, JL Hsu, ... Cancer research 76 (23), 7049-7058, 2016 | 61 | 2016 |
Phosphorylation of EZH2 at T416 by CDK2 contributes to the malignancy of triple negative breast cancers CC Yang, A LaBaff, Y Wei, L Nie, W Xia, L Huo, H Yamaguchi, YH Hsu, ... American journal of translational research 7 (6), 1009, 2015 | 46 | 2015 |
Overexpression of the pituitary tumor transforming gene induces p53-dependent senescence through activating DNA damage response pathway in normal human fibroblasts YH Hsu, LJ Liao, CH Yu, CP Chiang, JR Jhan, LC Chang, YJ Chen, ... Journal of Biological Chemistry 285 (29), 22630-22638, 2010 | 37 | 2010 |
Telomere and telomerase as targets for anti-cancer and regeneration therapies Y Hsu, J Lin Acta Pharmacologica Sinica 26 (5), 513-518, 2005 | 36 | 2005 |
Severe Hepatitis Promotes Hepatocellular Carcinoma Recurrence via NF-κB Pathway-Mediated Epithelial–Mesenchymal Transition after Resection TJ Wu, SS Chang, CW Li, YH Hsu, TC Chen, WC Lee, CT Yeh, MC Hung Clinical Cancer Research 22 (7), 1800-1812, 2016 | 32 | 2016 |
Association of pituitary tumor transforming gene expression with early oral tumorigenesis and malignant progression of precancerous lesions LJ Liao, YH Hsu, CH Yu, CP Chiang, JR Jhan, LC Chang, JJ Lin, PJ Lou Head & neck 33 (5), 719-726, 2011 | 17 | 2011 |
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation HH Lee, YN Wang, WH Yang, W Xia, Y Wei, LC Chan, YH Wang, Z Jiang, ... Nature communications 12 (1), 2788, 2021 | 16 | 2021 |
Chromosome positional effects of gene expressions after cellular senescence HL Chen, CY Lu, YH Hsu, JJ Lin Biochemical and biophysical research communications 313 (3), 576-586, 2004 | 11 | 2004 |
Early safety and efficacy from a phase I open-label clinical trial of CD137 (4-1BB) agonistic antibody LVGN6051 as monotherapy and in combination with pembrolizumab. S Fu, WA Harb, SP Patel, C Lu, DM Halperin, YH Hsu, N Shi, ... Journal of Clinical Oncology 39 (15_suppl), 2521-2521, 2021 | 7 | 2021 |
Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells OM Rahal, L Nie, LC Chan, CW Li, YH Hsu, J Hsu, D Yu, MC Hung American Journal of Cancer Research 5 (12), 3624, 2015 | 7 | 2015 |
Single oral dose acute and subacute toxicity of a c-MET tyrosine kinase inhibitor and CDK 4/6 inhibitor combination drug therapy B Smith, YH Hsu, R Flores, M Gagea, S Craig, MC Hung American Journal Of Cancer Research 8 (1), 183, 2018 | 6 | 2018 |