| An antidiabetic Thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor Γ (PPARγ)∗ JM Lehmann, LB Moore, TA Smith-Oliver, WO Wilkison, TM Willson, ... Journal of Biological Chemistry 270 (22), 12953-12956, 1995 | 4933 | 1995 |
| The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation M Ricote, AC Li, TM Willson, CJ Kelly, CK Glass Nature 391 (6662), 79-82, 1998 | 4625 | 1998 |
| Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ SA Kliewer, SS Sundseth, SA Jones, PJ Brown, GB Wisely, CS Koble, ... Proceedings of the National Academy of Sciences 94 (9), 4318-4323, 1997 | 2804 | 1997 |
| Bile acids: natural ligands for an orphan nuclear receptor DJ Parks, SG Blanchard, RK Bledsoe, G Chandra, TG Consler, ... Science 284 (5418), 1365-1368, 1999 | 2671 | 1999 |
| A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation SA Kliewer, JM Lenhard, TM Willson, I Patel, DC Morris, JM Lehmann Cell 83 (5), 813-819, 1995 | 2559 | 1995 |
| The PPARs: from orphan receptors to drug discovery TM Willson, PJ Brown, DD Sternbach, BR Henke Journal of medicinal chemistry 43 (4), 527-550, 2000 | 2490 | 2000 |
| Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ RT Nolte, GB Wisely, S Westin, JE Cobb, MH Lambert, R Kurokawa, ... Nature 395 (6698), 137-143, 1998 | 2486 | 1998 |
| A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis B Goodwin, SA Jones, RR Price, MA Watson, DD McKee, LB Moore, ... Molecular cell 6 (3), 517-526, 2000 | 2235 | 2000 |
| The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. JM Lehmann, DD McKee, MA Watson, TM Willson, JT Moore, SA Kliewer The Journal of clinical investigation 102 (5), 1016-1023, 1998 | 1972 | 1998 |
| An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway SA Kliewer, JT Moore, L Wade, JL Staudinger, MA Watson, SA Jones, ... Cell 92 (1), 73-82, 1998 | 1930 | 1998 |
| The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity JL Staudinger, B Goodwin, SA Jones, D Hawkins-Brown, KI MacKenzie, ... Proceedings of the National Academy of Sciences 98 (6), 3369-3374, 2001 | 1614 | 2001 |
| Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway JM Lehmann, SA Kliewer, LB Moore, TA Smith-Oliver, BB Oliver, JL Su, ... Journal of Biological Chemistry 272 (6), 3137-3140, 1997 | 1572 | 1997 |
| A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ G Pascual, AL Fong, S Ogawa, A Gamliel, AC Li, V Perissi, DW Rose, ... Nature 437 (7059), 759-763, 2005 | 1552 | 2005 |
| Molecular recognition of fatty acids by peroxisome proliferator–activated receptors HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ... Molecular cell 3 (3), 397-403, 1999 | 1528 | 1999 |
| A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport WR Oliver Jr, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ... Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001 | 1472 | 2001 |
| St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor LB Moore, B Goodwin, SA Jones, GB Wisely, CJ Serabjit-Singh, ... Proceedings of the National Academy of Sciences 97 (13), 7500-7502, 2000 | 1301 | 2000 |
| A unified nomenclature system for the nuclear receptor superfamily J Auwerx, E Baulieu, M Beato, M Becker-Andre, PH Burbach, G Camerino, ... Cell 97 (2), 161-163, 1999 | 1201 | 1999 |
| ApoE promotes the proteolytic degradation of Aβ Q Jiang, CYD Lee, S Mandrekar, B Wilkinson, P Cramer, N Zelcer, ... Neuron 58 (5), 681-693, 2008 | 1161 | 2008 |
| The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism SA Kliewer, B Goodwin, TM Willson Endocrine reviews 23 (5), 687-702, 2002 | 1144 | 2002 |
| Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor HR Kast, B Goodwin, PT Tarr, SA Jones, AM Anisfeld, CM Stoltz, ... Journal of Biological Chemistry 277 (4), 2908-2915, 2002 | 1142 | 2002 |
Steven KliewerProfessorAdresse e-mail validée de utsouthwestern.edu
