| Osteocyte control of bone formation via sclerostin, a novel BMP antagonist DG Winkler, MK Sutherland, JC Geoghegan, C Yu, T Hayes, JE Skonier, ... The EMBO journal, 2003 | 1413 | 2003 |
| Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ... Science 371 (6531), 823-829, 2021 | 316 | 2021 |
| Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation MK Sutherland, JC Geoghegan, C Yu, E Turcott, JE Skonier, DG Winkler, ... Bone 35 (4), 828-835, 2004 | 287 | 2004 |
| Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids NR Deleault, JR Piro, DJ Walsh, F Wang, J Ma, JC Geoghegan, ... Proceedings of the National Academy of Sciences 109 (22), 8546-8551, 2012 | 274 | 2012 |
| Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions NR Deleault, JC Geoghegan, K Nishina, R Kascsak, RA Williamson, ... Journal of Biological Chemistry 280 (29), 26873-26879, 2005 | 256 | 2005 |
| Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins DG Winkler, MSK Sutherland, E Ojala, E Turcott, JC Geoghegan, ... Journal of Biological Chemistry 280 (4), 2498-2502, 2005 | 200 | 2005 |
| Prolonged evolution of the human B cell response to SARS-CoV-2 infection M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ... Science immunology 6 (56), eabg6916, 2021 | 188 | 2021 |
| Noggin and sclerostin bone morphogenetic protein antagonists form a mutually inhibitory complex DG Winkler, C Yu, JC Geoghegan, EW Ojala, JE Skonier, D Shpektor, ... Journal of Biological Chemistry 279 (35), 36293-36298, 2004 | 177 | 2004 |
| Selective incorporation of polyanionic molecules into hamster prions JC Geoghegan, PA Valdes, NR Orem, NR Deleault, RA Williamson, ... Journal of Biological Chemistry 282 (50), 36341-36353, 2007 | 143 | 2007 |
| Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action JC Geoghegan, G Diedrich, X Lu, K Rosenthal, KF Sachsenmeier, H Wu, ... MAbs 8 (3), 454-467, 2016 | 124 | 2016 |
| Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro NR Deleault, R Kascsak, JC Geoghegan, S Supattapone Biochemistry 49 (18), 3928-3934, 2010 | 120 | 2010 |
| Cancelled operations: a 7-day cohort study of planned adult inpatient surgery in 245 UK National Health Service hospitals DJN Wong, SK Harris, SR Moonesinghe, SR Moonesinghe, DJN Wong, ... British journal of anaesthesia 121 (4), 730-738, 2018 | 117 | 2018 |
| Analgesic effectiveness of transversus abdominis plane blocks after hysterectomy: a meta-analysis R Champaneria, L Shah, J Geoghegan, JK Gupta, JP Daniels European Journal of Obstetrics & Gynecology and Reproductive Biology 166 (1 …, 2013 | 111 | 2013 |
| Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts MK Sutherland, JC Geoghegan, C Yu, DG Winkler, JA Latham Bone 35 (2), 448-454, 2004 | 107 | 2004 |
| Short Hairpin RNA–Mediated Inhibition of Matrix Metalloproteinase-1 in MDA-231 Cells: Effects on Matrix Destruction and Tumor Growth CA Wyatt, JC Geoghegan, CE Brinckerhoff Cancer research 65 (23), 11101-11108, 2005 | 89 | 2005 |
| Cell salvage at caesarean section: the need for an evidence‐based approach J Geoghegan, JP Daniels, PAS Moore, PJ Thompson, KS Khan, ... BJOG: An International Journal of Obstetrics & Gynaecology 116 (6), 743-747, 2009 | 85 | 2009 |
| Cell salvage and donor blood transfusion during cesarean section: a pragmatic, multicentre randomised controlled trial (SALVO) KS Khan, PAS Moore, MJ Wilson, R Hooper, S Allard, I Wrench, ... PLoS Medicine 14 (12), e1002471, 2017 | 76 | 2017 |
| Mitigation of reversible self-association and viscosity in a human IgG1 monoclonal antibody by rational, structure-guided Fv engineering JC Geoghegan, R Fleming, M Damschroder, SM Bishop, HA Sathish, ... MAbs 8 (5), 941-950, 2016 | 72 | 2016 |
| Trans-Dominant Inhibition of Prion Propagation In Vitro Is Not Mediated by an Accessory Cofactor JC Geoghegan, MB Miller, AH Kwak, BT Harris, S Supattapone PLoS pathogens 5 (7), e1000535, 2009 | 72 | 2009 |
| Copper (II) ions potently inhibit purified PrPres amplification NR Orem, JC Geoghegan, NR Deleault, R Kascsak, S Supattapone Journal of neurochemistry 96 (5), 1409-1415, 2006 | 71 | 2006 |
