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Jianwei Chen
Jianwei Chen
Adresse e-mail validée de bcm.edu
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Année
Quantitative real-time imaging of glutathione
X Jiang, J Chen, A Bajić, C Zhang, X Song, SL Carroll, ZL Cai, M Tang, ...
Nature communications 8 (1), 16087, 2017
2512017
Quantitative imaging of glutathione in live cells using a reversible reaction-based ratiometric fluorescent probe
X Jiang, Y Yu, J Chen, M Zhao, H Chen, X Song, AJ Matzuk, SL Carroll, ...
ACS chemical biology 10 (3), 864-874, 2015
1792015
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry
WH Guo, X Qi, X Yu, Y Liu, CI Chung, F Bai, X Lin, D Lu, L Wang, J Chen, ...
Nature communications 11 (1), 4268, 2020
1682020
Reversible reaction-based fluorescent probe for real-time imaging of glutathione dynamics in mitochondria
J Chen, X Jiang, C Zhang, KR MacKenzie, F Stossi, T Palzkill, MC Wang, ...
ACS sensors 2 (9), 1257-1261, 2017
1152017
Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3
X Song, J Chen, M Zhao, C Zhang, Y Yu, DM Lonard, DC Chow, T Palzkill, ...
Proceedings of the National Academy of Sciences 113 (18), 4970-4975, 2016
882016
Total Synthesis of (±)‐Merrilactone A
J Chen, P Gao, F Yu, Y Yang, S Zhu, H Zhai
Angewandte Chemie 24 (124), 5999-6001, 2012
862012
Theoretical and experimental investigation of thermodynamics and kinetics of thiol-michael addition reactions: a case study of reversible fluorescent probes for glutathione …
J Chen, X Jiang, SL Carroll, J Huang, J Wang
Organic letters 17 (24), 5978-5981, 2015
832015
Total Synthesis of (−)-Jiadifenin
Y Yang, X Fu, J Chen, H Zhai
Angewandte Chemie International Edition 51 (39), 9825-9828, 2012
722012
Tunable thioesters as “reduction” responsive functionality for traceless reversible protein PEGylation
J Chen, M Zhao, F Feng, A Sizovs, J Wang
Journal of the American Chemical Society 135 (30), 10938-10941, 2013
712013
Challenges and opportunities for small-molecule fluorescent probes in redox biology applications
L CarrollShaina, C WangMeng
Antioxidants & Redox Signaling, 2018
662018
Steroid receptor coactivator-3 (SRC-3/AIB1) as a novel therapeutic target in triple negative breast cancer and its inhibition with a phospho-bufalin prodrug
X Song, C Zhang, M Zhao, H Chen, X Liu, J Chen, DM Lonard, L Qin, J Xu, ...
PloS one 10 (10), e0140011, 2015
422015
Quantitative real-time imaging of glutathione with subcellular resolution
X Jiang, C Zhang, J Chen, S Choi, Y Zhou, M Zhao, X Song, X Chen, ...
Antioxidants & redox signaling 30 (16), 1900-1910, 2019
332019
Precisely tunable engineering of sub-30 nm monodisperse oligonucleotide nanoparticles
A Sizovs, X Song, MN Waxham, Y Jia, F Feng, J Chen, AC Wicker, J Xu, ...
Journal of the American Chemical Society 136 (1), 234-240, 2014
322014
Genetically anchored fluorescent probes for subcellular specific imaging of hydrogen sulfide
J Chen, M Zhao, X Jiang, A Sizovs, MC Wang, CR Provost, J Huang, ...
Analyst 141 (4), 1209-1213, 2016
232016
Development of improved SRC-3 inhibitors as breast cancer therapeutic agents
L Qin, J Chen, D Lu, P Jain, Y Yu, D Cardenas, X Peng, X Yu, J Xu, ...
Endocrine-related cancer 28 (10), 657-670, 2021
152021
Engineered Microglia‐Exosomes Coated Highly Twisting AIE Photothermal Agents to Efficiently Cross Blood‐Brain‐Barrier for Mild Photothermal‐Immune Checkpoint Blockade Therapy …
X Lin, Z Sun, S Huang, C Liu, J Peng, Y Li, Y Xiong, H Gao, J Chen, J Qi, ...
Advanced Functional Materials 34 (16), 2310237, 2024
122024
Diastereoselective Construction of Fused Carbocyclic Pyrrolidines via a Copper-Catalyzed [3+ 2] Cycloaddition: Total Syntheses of Pancratinines B–C
F Wang, X Xu, Y Yan, J Zhang, WJ Bai, J Chen, Y Yang
Organic Letters 25 (37), 6853-6857, 2023
62023
Small molecule regulators of steroid receptor coactivators and methods of use thereof
BW O'malley, DM Lonard, J Wang, J Xu, J Chen
US Patent 11,253,517, 2022
32022
Fluorescent probes and mass spectrometry-based methods to quantify thiols in biological systems
L Wang, F Jin, X Jiang, J Chen, MC Wang, J Wang
Antioxidants & Redox Signaling 36 (4-6), 354-365, 2022
32022
Glutathione quantification in live cells with real-time imaging and flow cytometry
X Jiang, J Chen, MC Wang, J Wang
STAR protocols 1 (3), 100170, 2020
32020
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