| Petabase-scale sequence alignment catalyses viral discovery RC Edgar, B Taylor, V Lin, T Altman, P Barbera, D Meleshko, D Lohr, ... Nature 602 (7895), 142-147, 2022 | 379 | 2022 |
| Obtaining genetics insights from deep learning via explainable artificial intelligence G Novakovsky, N Dexter, MW Libbrecht, WW Wasserman, S Mostafavi Nature Reviews Genetics 24 (2), 125-137, 2023 | 258 | 2023 |
| Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells NAJ Dawson, I Rosado-Sánchez, GE Novakovsky, VCW Fung, Q Huang, ... Science Translational Medicine 12 (557), eaaz3866, 2020 | 118 | 2020 |
| Biologically relevant transfer learning improves transcription factor binding prediction G Novakovsky, M Saraswat, O Fornes, S Mostafavi, WW Wasserman Genome biology 22, 1-25, 2021 | 44 | 2021 |
| A sustained deficiency of mitochondrial respiratory complex III induces an apoptotic cell death through the p53-mediated inhibition of pro-survival activities of the activating … AG Evstafieva, AA Garaeva, AA Khutornenko, AV Klepikova, ... Cell death & disease 5 (11), e1511-e1511, 2014 | 37 | 2014 |
| ExplaiNN: interpretable and transparent neural networks for genomics G Novakovsky, O Fornes, M Saraswat, S Mostafavi, WW Wasserman Genome Biology 24 (1), 154, 2023 | 31 | 2023 |
| Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion C Lamarche, K Ward-Hartstonge, T Mi, DTS Lin, Q Huang, A Brown, ... Proceedings of the National Academy of Sciences 120 (14), e2219086120, 2023 | 31 | 2023 |
| Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia X Niu, K Rothe, M Chen, S Grasedieck, R Li, SE Nam, X Zhang, ... Blood, The Journal of the American Society of Hematology 137 (26), 3641-3655, 2021 | 30 | 2021 |
| A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency IRFI CONSORTIUM Science Immunology 8 (79), 2023 | 14 | 2023 |
| In silico discovery of small molecules for efficient stem cell differentiation into definitive endoderm G Novakovsky, S Sasaki, O Fornes, ME Omur, H Huang, CL Bayly, ... Stem Cell Reports 18 (3), 765-781, 2023 | 13 | 2023 |
| Using transcriptomic hidden variables to infer context-specific genotype effects in the brain B Ng, W Casazza, E Patrick, S Tasaki, G Novakovsky, D Felsky, Y Ma, ... The American Journal of Human Genetics 105 (3), 562-572, 2019 | 13 | 2019 |
| Repeated stimulation or tonic-signaling chimeric antigen receptors drive regulatory T cell exhaustion C Lamarche, GE Novakovsky, CN Qi, EW Weber, CL Mackall, MK Levings bioRxiv, 2020.06. 27.175158, 2020 | 9 | 2020 |
| Phylogenomic analysis of type 1 NADH: quinone oxidoreductase GE Novakovsky, DV Dibrova, AY Mulkidjanian Biochemistry (Moscow) 81, 770-784, 2016 | 8 | 2016 |
| bioSyntax: syntax highlighting for computational biology A Babaian, A Ebou, A Fegen, HY Kam, GE Novakovsky, J Wong, D Aïssi, ... BMC bioinformatics 19, 1-6, 2018 | 4 | 2018 |
| Functional effects of chimeric antigen receptor co-receptor signaling domains in human Tregs NAJ Dawson, I Rosado-Sánchez, GE Novakovsky, VCW Fung, Q Huang, ... BioRxiv, 749721, 2019 | 3 | 2019 |
| Advancing our understanding of genome regulation via optimization of stem cell differentiation and interpretable deep learning G Novakovskiy University of British Columbia, 2022 | | 2022 |
| Targeting AXL Kinase Sensitizes Acute Myeloid Leukemia Stem and Progenitor Cells to Venetoclax Treatment K Rothe, X Niu, M Chen, R Li, S Nam, X Zhang, G Novakovskiy, Y Ahn, ... Blood 136, 20, 2020 | | 2020 |
| Biologically-relevant transfer learning improves transcription factor binding prediction WW Gherman Novakovsky, Manu Saraswat, Oriol Fornes, Sara Mostafavi | | 2020 |
| Phylogenomic analysis of the type I NADH: quinone-oxidoreductase GE Novakovsky, DV Dibrova, AY Mulkidjanian Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857, e42-e43, 2016 | | 2016 |
| Carmen L. Bayly, Dahai Zhang, Nathaniel Lim, 2, 6 Artem Cherkasov, 7 Paul Pavlidis, 6 Sara Mostafavi, Francis C. Lynn,* and Wyeth W. Wasserman G Novakovsky, S Sasaki, O Fornes, ME Omur, H Huang | | |
Wyeth WassermanProfessor of Medical Genetics, University of British ColumbiaAdresse e-mail validée de cmmt.ubc.ca