| An antidiabetic Thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor Γ (PPARγ)∗ JM Lehmann, LB Moore, TA Smith-Oliver, WO Wilkison, TM Willson, ... Journal of Biological Chemistry 270 (22), 12953-12956, 1995 | 4931 | 1995 |
| Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ SA Kliewer, SS Sundseth, SA Jones, PJ Brown, GB Wisely, CS Koble, ... Proceedings of the National Academy of Sciences 94 (9), 4318-4323, 1997 | 2802 | 1997 |
| Bile acids: natural ligands for an orphan nuclear receptor DJ Parks, SG Blanchard, RK Bledsoe, G Chandra, TG Consler, ... Science 284 (5418), 1365-1368, 1999 | 2670 | 1999 |
| A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation SA Kliewer, JM Lenhard, TM Willson, I Patel, DC Morris, JM Lehmann Cell 83 (5), 813-819, 1995 | 2559 | 1995 |
| A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis B Goodwin, SA Jones, RR Price, MA Watson, DD McKee, LB Moore, ... Molecular cell 6 (3), 517-526, 2000 | 2234 | 2000 |
| Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors SA Kliewer, K Umesono, DJ Noonan, RA Heyman, RM Evans Nature 358 (6389), 771-774, 1992 | 2209 | 1992 |
| Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis T Inagaki, M Choi, A Moschetta, LI Peng, CL Cummins, JG McDonald, ... Cell metabolism 2 (4), 217-225, 2005 | 2047 | 2005 |
| The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. JM Lehmann, DD McKee, MA Watson, TM Willson, JT Moore, SA Kliewer The Journal of clinical investigation 102 (5), 1016-1023, 1998 | 1972 | 1998 |
| An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway SA Kliewer, JT Moore, L Wade, JL Staudinger, MA Watson, SA Jones, ... Cell 92 (1), 73-82, 1998 | 1929 | 1998 |
| Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. SA Kliewer, BM Forman, B Blumberg, ES Ong, U Borgmeyer, ... Proceedings of the National Academy of Sciences 91 (15), 7355-7359, 1994 | 1839 | 1994 |
| Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling SA Kliewer, K Umesono, DJ Mangelsdorf, RM Evans Nature 355 (6359), 446-449, 1992 | 1793 | 1992 |
| Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21 T Inagaki, P Dutchak, G Zhao, X Ding, L Gautron, V Parameswara, Y Li, ... Cell metabolism 5 (6), 415-425, 2007 | 1774 | 2007 |
| The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity JL Staudinger, B Goodwin, SA Jones, D Hawkins-Brown, KI MacKenzie, ... Proceedings of the National Academy of Sciences 98 (6), 3369-3374, 2001 | 1614 | 2001 |
| Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway JM Lehmann, SA Kliewer, LB Moore, TA Smith-Oliver, BB Oliver, JL Su, ... Journal of Biological Chemistry 272 (6), 3137-3140, 1997 | 1572 | 1997 |
| Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs JM Lehmann, JM Lenhard, BB Oliver, GM Ringold, SA Kliewer Journal of Biological Chemistry 272 (6), 3406-3410, 1997 | 1550 | 1997 |
| Molecular recognition of fatty acids by peroxisome proliferator–activated receptors HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ... Molecular cell 3 (3), 397-403, 1999 | 1528 | 1999 |
| Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor R Schüle, P Rangarajan, S Kliewer, LJ Ransone, J Bolado, N Yang, ... Cell 62 (6), 1217-1226, 1990 | 1501 | 1990 |
| A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport WR Oliver Jr, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ... Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001 | 1473 | 2001 |
| St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor LB Moore, B Goodwin, SA Jones, GB Wisely, CJ Serabjit-Singh, ... Proceedings of the National Academy of Sciences 97 (13), 7500-7502, 2000 | 1302 | 2000 |
| Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor T Inagaki, A Moschetta, YK Lee, L Peng, G Zhao, M Downes, RT Yu, ... Proceedings of the National Academy of Sciences 103 (10), 3920-3925, 2006 | 1282 | 2006 |
