Qualitatively and quantitatively investigating the regulation of intestinal microbiota on the metabolism of panax notoginseng saponins J Xiao, H Chen, D Kang, Y Shao, B Shen, X Li, X Yin, Z Zhu, H Li, T Rao, ... Journal of Ethnopharmacology 194, 324-336, 2016 | 52 | 2016 |
Acetaminophen-induced liver injury alters expression and activities of cytochrome P450 enzymes in an age-dependent manner in mouse liver Y Bao, P Wang, X Shao, J Zhu, J Xiao, J Shi, L Zhang, HJ Zhu, X Ma, ... Drug Metabolism and Disposition 48 (5), 326-336, 2020 | 38 | 2020 |
In vitro screening of environmental chemicals identifies zearalenone as a novel substrate of the placental BCRP/ABCG2 transporter J Xiao, Q Wang, KM Bircsak, X Wen, LM Aleksunes Toxicology research 4 (3), 695-706, 2015 | 30 | 2015 |
Low cerebral exposure cannot hinder the neuroprotective effects of panax notoginsenosides H Li, J Xiao, X Li, H Chen, D Kang, Y Shao, B Shen, Z Zhu, X Yin, L Xie, ... Drug Metabolism and Disposition 46 (1), 53-65, 2018 | 28 | 2018 |
Comprehensive characterization of the in vitro and in vivo metabolites of ziyuglycoside I in rat microsome, intestinal flora, excretion specimen and fresh tissues based on LC–Q … G Wang, H Fu, W Ye, X Zheng, J Xiao, D Kang, T Rao, Y Shao, L Xie, ... Journal of Pharmaceutical and Biomedical Analysis 128, 191-200, 2016 | 27 | 2016 |
Development and validation of an UFLC–MS/MS assay for the absolute quantitation of nine notoginsenosides in rat plasma: Application to the pharmacokinetic study of Panax … L Zhou, R Xing, L Xie, T Rao, Q Wang, W Ye, H Fu, J Xiao, Y Shao, ... Journal of Chromatography B 995, 46-53, 2015 | 25 | 2015 |
Biliary excretion–mediated food effects and prediction J Xiao, D Tran, X Zhang, T Zhang, S Seo, H Zhu, P Zou The AAPS Journal 22, 1-10, 2020 | 12 | 2020 |
Development of a novel sectional multiple filtering scheme for rapid screening and classifying metabolites of ziyuglycoside II in rat liver and excreta specimen based on high … J Xiao, H Chen, H Fu, W Ye, T Rao, Y Shao, D Kang, B Shen, L Xie, ... Journal of Pharmaceutical and Biomedical Analysis 129, 310-319, 2016 | 11 | 2016 |
PK study of octreotide based on LC–MS/MS combining protein precipitation and impurity extraction technique Q Wang, Y Liang, T Rao, L Xie, W Ye, H Fu, L Zhou, R Xing, Y Shao, ... Bioanalysis 7 (7), 885-894, 2015 | 11 | 2015 |
Developing a SWATH capillary LC-MS/MS method for simultaneous therapeutic drug monitoring and untargeted metabolomics analysis of neonatal plasma J Xiao, J Shi, R Li, L Her, X Wang, J Li, MJ Sorensen, V Bhatt-Mehta, ... Journal of Chromatography B 1179, 122865, 2021 | 10 | 2021 |
Impact of carboxylesterase 1 genetic polymorphism on trandolapril activation in human liver and the pharmacokinetics and pharmacodynamics in healthy volunteers X Wang, L Her, J Xiao, J Shi, AH Wu, BE Bleske, HJ Zhu Clinical and translational science 14 (4), 1380-1389, 2021 | 10 | 2021 |
Bioanalytical assay development and validation for simultaneous quantification of five schisandra lignans in rat primary hepatocytes based on LC‐MS/MS: application to a real … D Kang, Y Shao, X Yin, J Xiao, T Rao, B Shen, H Chen, Z Zhu, G Wang, ... Biomedical Chromatography 31 (2), e3797, 2017 | 9 | 2017 |
Development and validation of a quantification method for ziyuglycoside I and II in rat plasma: Application to their pharmacokinetic studies W Ye, H Fu, L Xie, L Zhou, T Rao, Q Wang, Y Shao, J Xiao, D Kang, ... Journal of Separation Science 38 (13), 2340-2347, 2015 | 8 | 2015 |
Plasma Carboxylesterase 1 Predicts Methylphenidate Exposure: A Proof‐of‐Concept Study Using Plasma Protein Biomarker for Hepatic Drug Metabolism J Shi, J Xiao, X Wang, SM Jung, BE Bleske, JS Markowitz, KS Patrick, ... Clinical Pharmacology & Therapeutics 111 (4), 878-885, 2022 | 7 | 2022 |
FRACPRED‐2D‐PRM: a fraction prediction algorithm‐assisted 2D liquid chromatography‐based parallel reaction monitoring‐mass spectrometry approach for measuring low‐abundance … J Shi, J Xiao, J Li, X Wang, L Her, MJ Sorensen, HJ Zhu Proteomics 20 (24), 2000175, 2020 | 6 | 2020 |
Physiologically-based pharmacokinetic modeling to predict methylphenidate exposure affected by interplay among carboxylesterase 1 pharmacogenetics, drug-drug interactions, and sex J Xiao, J Shi, BR Thompson, DE Smith, T Zhang, HJ Zhu Journal of pharmaceutical sciences 111 (9), 2606-2613, 2022 | 5 | 2022 |
Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir … J Li, J Shi, J Xiao, L Tran, X Wang, HJ Zhu Drug Metabolism and Disposition 50 (3), 243-248, 2022 | 4 | 2022 |
The metabolic and pharmacokinetic studies for HM-3 in rats based on LC-Q-TOF/MS and LC–MS/MS combing a convenient biological sample processing method G Wang, T Rao, Y Shao, J Xiao, D Kang, B Shen, H Chen, X Li, Z Zhu, ... Journal of Chromatography B 1031, 68-75, 2016 | 4 | 2016 |
A robust LC–MS/MS method for the determination of pidotimod in different biological matrixes and its application to in vivo and in vitro pharmacokinetic studies G Wang, Q Wang, T Rao, B Shen, D Kang, Y Shao, J Xiao, H Chen, ... Journal of Chromatography B 1023, 36-43, 2016 | 1 | 2016 |
Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are … J Li, DM de Melo Jorge, W Wang, S Sun, T Frum, YA Hang, Y Liu, X Zhou, ... Journal of Medicinal Chemistry 67 (9), 7470-7486, 2024 | | 2024 |