Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex I Bhutto, G Lutty Molecular aspects of medicine 33 (4), 295-317, 2012 | 1180 | 2012 |
Relationship between RPE and choriocapillaris in age-related macular degeneration DS McLeod, R Grebe, I Bhutto, C Merges, T Baba, GA Lutty Investigative ophthalmology & visual science 50 (10), 4982-4991, 2009 | 654 | 2009 |
Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with age-related macular degeneration IA Bhutto, DS McLeod, T Hasegawa, SY Kim, C Merges, P Tong, GA Lutty Experimental eye research 82 (1), 99-110, 2006 | 389 | 2006 |
Histopathological insights into choroidal vascular loss in clinically documented cases of age-related macular degeneration JM Seddon, DS McLeod, IA Bhutto, MB Villalonga, RE Silver, AS Wenick, ... JAMA ophthalmology 134 (11), 1272-1280, 2016 | 201 | 2016 |
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4 X Xin, M Rodrigues, M Umapathi, F Kashiwabuchi, T Ma, ... Proceedings of the National Academy of Sciences 110 (36), E3425-E3434, 2013 | 172 | 2013 |
VEGF secreted by hypoxic Müller cells induces MMP-2 expression and activity in endothelial cells to promote retinal neovascularization in proliferative diabetic retinopathy M Rodrigues, X Xin, K Jee, S Babapoor-Farrokhran, F Kashiwabuchi, ... Diabetes 62 (11), 3863-3873, 2013 | 158 | 2013 |
Small-molecule–directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells J Maruotti, SR Sripathi, K Bharti, J Fuller, KJ Wahlin, V Ranganathan, ... Proceedings of the National Academy of Sciences 112 (35), 10950-10955, 2015 | 144 | 2015 |
C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration IA Bhutto, T Baba, C Merges, V Juriasinghani, DS McLeod, GA Lutty British Journal of Ophthalmology 95 (9), 1323-1330, 2011 | 144 | 2011 |
Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling M Valapala, C Wilson, S Hose, IA Bhutto, R Grebe, A Dong, S Greenbaum, ... Autophagy 10 (3), 480-496, 2014 | 142 | 2014 |
The expression of advanced glycation endproduct receptors in rpe cells associated with basal deposits in human maculas Y Yamada, K Ishibashi, K Ishibashi, IA Bhutto, J Tian, GA Lutty, JT Handa Experimental eye research 82 (5), 840-848, 2006 | 142 | 2006 |
Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium TW Prow, I Bhutto, SY Kim, R Grebe, C Merges, DS McLeod, K Uno, ... Nanomedicine: nanotechnology, biology, and medicine 4 (4), 340, 2008 | 136 | 2008 |
A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells J Maruotti, K Wahlin, D Gorrell, I Bhutto, G Lutty, DJ Zack Stem cells translational medicine 2 (5), 341-354, 2013 | 127 | 2013 |
Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration IA Bhutto, SY Kim, DS McLeod, C Merges, N Fukai, BR Olsen, GA Lutty Investigative ophthalmology & visual science 45 (5), 1544-1552, 2004 | 123 | 2004 |
Poly(β-Amino Ester)-Nanoparticle Mediated Transfection of Retinal Pigment Epithelial Cells In Vitro and In Vivo JC Sunshine, SB Sunshine, I Bhutto, JT Handa, JJ Green PloS one 7 (5), e37543, 2012 | 118 | 2012 |
Distribution and quantification of choroidal macrophages in human eyes with age-related macular degeneration DS McLeod, I Bhutto, MM Edwards, RE Silver, JM Seddon, GA Lutty Investigative ophthalmology & visual science 57 (14), 5843-5855, 2016 | 108 | 2016 |
Development of the human choriocapillaris GA Lutty, T Hasegawa, T Baba, R Grebe, I Bhutto, DS McLeod Eye 24 (3), 408-415, 2010 | 107 | 2010 |
Low nitric oxide synthases (NOSs) in eyes with age-related macular degeneration (AMD) IA Bhutto, T Baba, C Merges, DS McLeod, GA Lutty Experimental eye research 90 (1), 155-167, 2010 | 105 | 2010 |
Systemic and intravitreal delivery of dendrimers to activated microglia/macrophage in ischemia/reperfusion mouse retina SP Kambhampati, AJM Clunies-Ross, I Bhutto, MK Mishra, M Edwards, ... Investigative ophthalmology & visual science 56 (8), 4413-4424, 2015 | 100 | 2015 |
Vascular progenitors from cord blood–derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature TS Park, I Bhutto, L Zimmerlin, JS Huo, P Nagaria, D Miller, AJ Rufaihah, ... Circulation 129 (3), 359-372, 2014 | 100 | 2014 |
Effect of VEGF trap on normal retinal vascular development and oxygen-induced retinopathy in the dog GA Lutty, DS McLeod, I Bhutto, SJ Wiegand Investigative Ophthalmology & Visual Science 52 (7), 4039-4047, 2011 | 92 | 2011 |